Detalhe da pesquisa
1.
Synthesis and pharmacological characterization of functionalized 6-piperazin-1-yl-purines as cannabinoid receptor 1 (CB1) inverse agonists.
Bioorg Med Chem
; 26(15): 4518-4531, 2018 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30077609
2.
The amide linker in nonpeptide neurotensin receptor ligands plays a key role in calcium signaling at the neurotensin receptor type 2.
Bioorg Med Chem Lett
; 25(10): 2060-4, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25881832
3.
Identification of N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-l-leucine (NTRC-808), a novel nonpeptide chemotype selective for the neurotensin receptor type 2.
Bioorg Med Chem Lett
; 25(2): 292-6, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25499438
4.
Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor.
J Med Chem
; 61(10): 4370-4385, 2018 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29688015
5.
Identification of 2-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.13,7]decane-2-carboxylic Acid (NTRC-844) as a Selective Antagonist for the Rat Neurotensin Receptor Type 2.
ACS Chem Neurosci
; 7(9): 1225-31, 2016 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27359371
6.
Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.
Comb Chem High Throughput Screen
; 8(4): 327-39, 2005 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16101009
7.
Identification of N-[(5-{[(4-methylphenyl)sulfonyl]amino}-3-(trifluoroacetyl)-1H-indol-1-yl)acetyl]-l-leucine (NTRC-824), a neurotensin-like nonpeptide compound selective for the neurotensin receptor type 2.
J Med Chem
; 57(17): 7472-7, 2014 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25157640
8.
Identification of 1-({[1-(4-fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane carboxylic acid as a selective nonpeptide neurotensin receptor type 2 compound.
J Med Chem
; 57(12): 5318-32, 2014 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24856674
9.
Identification and characterization of 4-chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a selective and irreversible peroxisome proliferator-activated receptor delta (PPARdelta) antagonist.
J Med Chem
; 53(4): 1857-61, 2010 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20128594
10.
Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.
J Med Chem
; 51(18): 5758-65, 2008 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18800767
11.
Array synthesis of progesterone receptor antagonists: 3-aryl-1,2-diazepines.
Bioorg Med Chem Lett
; 16(14): 3777-9, 2006 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16678409