Detalhe da pesquisa
1.
A novel functional role for the classic CNS neurotransmitters, GABA, glycine, and glutamate, in the kidney: potent and opposing regulators of the renal vasculature.
Am J Physiol Renal Physiol
; 325(1): F38-F49, 2023 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37102686
2.
Evaluating Scalable Supervised Learning for Synthesize-on-Demand Chemical Libraries.
J Chem Inf Model
; 63(17): 5513-5528, 2023 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37625010
3.
Discovery and Mechanism of Small Molecule Inhibitors Selective for the Chromatin-Binding Domains of Oncogenic UHRF1.
Biochemistry
; 61(5): 354-366, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35143176
4.
TRPV4 receptor as a functional sensory molecule in bladder urothelium: Stretch-independent, tissue-specific actions and pathological implications.
FASEB J
; 34(1): 263-286, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914645
5.
Predicting kinase inhibitors using bioactivity matrix derived informer sets.
PLoS Comput Biol
; 15(8): e1006813, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31381559
6.
Practical Model Selection for Prospective Virtual Screening.
J Chem Inf Model
; 59(1): 282-293, 2019 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30500183
7.
Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening.
J Chem Inf Model
; 57(7): 1579-1590, 2017 07 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28654262
8.
Altered urothelial ATP signaling in a major subset of human overactive bladder patients with pyuria.
Am J Physiol Renal Physiol
; 311(4): F805-F816, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27358056
9.
Isoform-selective inhibition of facilitative glucose transporters: elucidation of the molecular mechanism of HIV protease inhibitor binding.
J Biol Chem
; 289(23): 16100-13, 2014 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24706759
10.
Nonsteroidal anti-inflammatory drugs alter vasa recta diameter via pericytes.
Am J Physiol Renal Physiol
; 309(7): F648-57, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26202223
11.
Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.
Bioorg Med Chem
; 23(10): 2328-43, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25882520
12.
Urinary ATP as an indicator of infection and inflammation of the urinary tract in patients with lower urinary tract symptoms.
BMC Urol
; 15: 7, 2015 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25886951
13.
Small Molecule Antagonists of the DNA Repair ERCC1/XPA Protein-Protein Interaction.
ChemMedChem
; 19(8): e202300648, 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38300970
14.
The natural product dihydrotanshinone I provides a prototype for uncharged inhibitors that bind specifically to the acetylcholinesterase peripheral site with nanomolar affinity.
Biochemistry
; 52(42): 7486-99, 2013 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-24040835
15.
Inflammatory mediators act at renal pericytes to elicit contraction of vasa recta and reduce pericyte density along the kidney medullary vascular network.
Front Physiol
; 14: 1194803, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37362447
16.
Simultaneous quantification of 12 different nucleotides and nucleosides released from renal epithelium and in human urine samples using ion-pair reversed-phase HPLC.
Purinergic Signal
; 8(4): 741-51, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22707011
17.
High Throughput Small Molecule Screen for Reactivation of FMR1 in Fragile X Syndrome Human Neural Cells.
Cells
; 11(1)2021 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35011630
18.
Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration.
Am J Physiol Gastrointest Liver Physiol
; 299(1): G32-42, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20185692
19.
Nucleotides downregulate aquaporin 2 via activation of apical P2 receptors.
J Am Soc Nephrol
; 20(7): 1480-90, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19423692
20.
ENaC, renal sodium excretion and extracellular ATP.
Purinergic Signal
; 5(4): 481-9, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19306075