Detalhe da pesquisa
1.
Discovery of novel dihydrobenzofuran cyclopropane carboxylic acid based calcium sensing receptor antagonists for the treatment of osteoporosis.
Bioorg Med Chem Lett
; 26(16): 4077-80, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27397499
2.
Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers.
Mol Syst Biol
; 8: 594, 2012 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22806142
3.
Identification and characterization of lipopolysaccharide binding protein (LBP) as an estrogen receptor α specific serum biomarker.
Biomarkers
; 17(2): 172-9, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22299632
4.
SHR1032, a novel STING agonist, stimulates anti-tumor immunity and directly induces AML apoptosis.
Sci Rep
; 12(1): 8579, 2022 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35595822
5.
Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington's Disease Pathology.
J Med Chem
; 65(18): 12445-12459, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36098485
6.
Functional genomic maps in Caenorhabditis elegans.
Curr Opin Cell Biol
; 15(2): 206-12, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12648677
7.
Non-invasive muscle contraction assay to study rodent models of sarcopenia.
BMC Musculoskelet Disord
; 12: 246, 2011 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22035016
8.
Shape deformation analysis reveals the temporal dynamics of cell-type-specific homeostatic and pathogenic responses to mutant huntingtin.
Elife
; 102021 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33618800
9.
FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.
Cell Rep
; 36(9): 109649, 2021 08 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34469738
10.
Estrogen-related receptor-alpha antagonist inhibits both estrogen receptor-positive and estrogen receptor-negative breast tumor growth in mouse xenografts.
Mol Cancer Ther
; 8(3): 672-81, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19276159
11.
Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.
Neuron
; 107(5): 891-908.e8, 2020 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32681824
12.
DNA methylation study of Huntington's disease and motor progression in patients and in animal models.
Nat Commun
; 11(1): 4529, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32913184
13.
Facilitating Huntington's disease research: plasma neurofilament levels as a promising enrichment biomarker for HD-ISS stage 1.
EBioMedicine
; 94: 104710, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37442063
14.
A novel selective androgen receptor modulator (SARM) MK-4541 exerts anti-androgenic activity in the prostate cancer xenograft R-3327G and anabolic activity on skeletal muscle mass & function in castrated mice.
J Steroid Biochem Mol Biol
; 163: 88-97, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27106747
15.
Direct agonist/antagonist functions of dehydroepiandrosterone.
Endocrinology
; 146(11): 4568-76, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15994348
16.
Somatostatin receptor subtype 5 regulates insulin secretion and glucose homeostasis.
Mol Endocrinol
; 17(1): 93-106, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12511609
17.
Identification and characterization of a functionally distinct form of human estrogen receptor beta.
Endocrinology
; 143(4): 1558-61, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-11897716
18.
Immunolocalization of estrogen receptor beta in the mouse brain: comparison with estrogen receptor alpha.
Endocrinology
; 144(5): 2055-67, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12697714
19.
Identification of an anabolic selective androgen receptor modulator that actively induces death of androgen-independent prostate cancer cells.
J Steroid Biochem Mol Biol
; 143: 29-39, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24565564
20.
Increased muscle force production and bone mineral density in ActRIIB-Fc-treated mature rodents.
J Gerontol A Biol Sci Med Sci
; 68(10): 1181-92, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23525481