Detalhe da pesquisa
1.
Myelin dysfunction drives amyloid-ß deposition in models of Alzheimer's disease.
Nature
; 618(7964): 349-357, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37258678
2.
Pathways linking aging and atheroprotection in Mif-deficient atherosclerotic mice.
FASEB J
; 37(3): e22752, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36794636
3.
Seeding, maturation and propagation of amyloid ß-peptide aggregates in Alzheimer's disease.
Brain
; 145(10): 3558-3570, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36270003
4.
Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in AppNL-G-F mice.
Neuroimage
; 230: 117707, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33385560
5.
Young microglia restore amyloid plaque clearance of aged microglia.
EMBO J
; 36(5): 583-603, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28007893
6.
η-Secretase processing of APP inhibits neuronal activity in the hippocampus.
Nature
; 526(7573): 443-7, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26322584
7.
Aß-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein.
Acta Neuropathol
; 138(6): 913-941, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31414210
8.
Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein.
Biochim Biophys Acta Mol Cell Res
; 1864(1): 217-230, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27818272
9.
Diffusible, highly bioactive oligomers represent a critical minority of soluble Aß in Alzheimer's disease brain.
Acta Neuropathol
; 136(1): 19-40, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29687257
10.
Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
J Biol Chem
; 291(1): 318-33, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26574544
11.
Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.
EMBO J
; 32(14): 2015-28, 2013 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-23792428
12.
Secretome protein enrichment identifies physiological BACE1 protease substrates in neurons.
EMBO J
; 31(14): 3157-68, 2012 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22728825
13.
Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions.
J Neurosci
; 33(32): 12915-28, 12928a, 2013 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23926248
14.
Dual cleavage of neuregulin 1 type III by BACE1 and ADAM17 liberates its EGF-like domain and allows paracrine signaling.
J Neurosci
; 33(18): 7856-69, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23637177
15.
Loss of Bace2 in zebrafish affects melanocyte migration and is distinct from Bace1 knock out phenotypes.
J Neurochem
; 127(4): 471-81, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23406323
16.
Age-dependent NMDA receptor function is regulated by the amyloid precursor protein.
Aging Cell
; 22(3): e13778, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36704841
17.
Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase.
J Neurosci
; 31(5): 1885-94, 2011 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21289198
18.
Translational repression of the disintegrin and metalloprotease ADAM10 by a stable G-quadruplex secondary structure in its 5'-untranslated region.
J Biol Chem
; 286(52): 45063-72, 2011 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22065584
19.
Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.
Glia
; 60(2): 203-17, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22052506
20.
A molecular view of human amyloid-ß folds.
Science
; 375(6577): 147-148, 2022 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35025652