Detalhe da pesquisa
1.
Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling.
Proc Natl Acad Sci U S A
; 117(38): 23617-23625, 2020 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32879008
2.
Perampanel and decanoic acid show synergistic action against AMPA receptors and seizures.
Epilepsia
; 59(11): e172-e178, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30324610
3.
Synapsin I phosphorylation is dysregulated by beta-amyloid oligomers and restored by valproic acid.
Neurobiol Dis
; 106: 63-75, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28647556
4.
Seizure control by decanoic acid through direct AMPA receptor inhibition.
Brain
; 139(Pt 2): 431-43, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26608744
5.
An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba Dictyostelium discoideum.
J Cell Sci
; 127(Pt 7): 1576-84, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24463814
6.
A novel human receptor involved in bitter tastant detection identified using Dictyostelium discoideum.
J Cell Sci
; 126(Pt 23): 5465-76, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24006265
7.
Seizure control by derivatives of medium chain fatty acids associated with the ketogenic diet show novel branching-point structure for enhanced potency.
J Pharmacol Exp Ther
; 352(1): 43-52, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25326131
8.
New experimental therapies for status epilepticus in preclinical development.
Epilepsy Behav
; 49: 290-3, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26189787
9.
Seizure-induced reduction in PIP3 levels contributes to seizure-activity and is rescued by valproic acid.
Neurobiol Dis
; 62: 296-306, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24148856
10.
The Rac GEF ZizB regulates development, cell motility and cytokinesis in Dictyostelium.
J Cell Sci
; 125(Pt 10): 2457-65, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22366457
11.
Functional mechanism study of the allelochemical myrigalone A identifies a group of ultrapotent inhibitors of ethylene biosynthesis in plants.
Plant Commun
; : 100846, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38460510
12.
Molecular pharmacology in a simple model system: implicating MAP kinase and phosphoinositide signalling in bipolar disorder.
Semin Cell Dev Biol
; 22(1): 105-13, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21093602
13.
Identifying an uptake mechanism for the antiepileptic and bipolar disorder treatment valproic acid using the simple biomedical model Dictyostelium.
J Cell Sci
; 124(Pt 13): 2267-76, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21652627
14.
The search for better epilepsy treatments: from slime mould to coconuts.
Biochem Soc Trans
; 41(6): 1625-8, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24256265
15.
Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a Drosophila Model of Amyotrophic Lateral Sclerosis.
Cells
; 12(17)2023 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37681895
16.
Enhanced Sestrin expression through Tanshinone 2A treatment improves PI3K-dependent inhibition of glioma growth.
Cell Death Discov
; 9(1): 172, 2023 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37202382
17.
Quantitative determination of SLC2A1 variant functional effects in GLUT1 deficiency syndrome.
Ann Clin Transl Neurol
; 10(5): 787-801, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37000947
18.
Anti-emetic effects of thalidomide: Evidence, mechanism of action, and future directions.
Curr Res Pharmacol Drug Discov
; 3: 100138, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36568268
19.
Structural basis of AMPA receptor inhibition by trans-4-butylcyclohexane carboxylic acid.
Br J Pharmacol
; 179(14): 3628-3644, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32959886
20.
Using Dictyostelium to Advance Our Understanding of the Role of Medium Chain Fatty Acids in Health and Disease.
Front Cell Dev Biol
; 9: 722066, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34589488