Detalhe da pesquisa
1.
LOGGIC/FIREFLY-2: a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration.
BMC Cancer
; 24(1): 147, 2024 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38291372
2.
INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies.
BMC Cancer
; 20(1): 523, 2020 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32503469
3.
Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions-A calibration approach.
Biom J
; 61(3): 488-502, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30175405
4.
Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM.
JCO Precis Oncol
; 7: e2300015, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37364231
5.
A Study of Regulatory Challenges of Pediatric Oncology Phase I/II Trial Submissions and Guidance on Protocol Development.
Clin Pharmacol Ther
; 110(4): 1025-1037, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34050933
6.
Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia.
Clin Epigenetics
; 11(1): 188, 2019 12 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31823832
7.
Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience.
Eur J Cancer
; 114: 27-35, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31022591
8.
Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.
Brain Pathol
; 26(4): 506-16, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26445087
9.
Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study.
Eur J Cancer
; 65: 91-101, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27479119