Detalhe da pesquisa
1.
Ultrapotent influenza hemagglutinin fusion inhibitors developed through SuFEx-enabled high-throughput medicinal chemistry.
Proc Natl Acad Sci U S A
; 121(22): e2310677121, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753503
2.
Diversity oriented clicking delivers ß-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors.
Proc Natl Acad Sci U S A
; 119(37): e2208540119, 2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36070343
3.
Quantitative Metaproteomics and Activity-based Protein Profiling of Patient Fecal Microbiome Identifies Host and Microbial Serine-type Endopeptidase Activity Associated With Ulcerative Colitis.
Mol Cell Proteomics
; 21(3): 100197, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35033677
4.
An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.
Proc Natl Acad Sci U S A
; 117(31): 18431-18438, 2020 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690700
5.
Discovery of small-molecule enzyme activators by activity-based protein profiling.
Nat Chem Biol
; 16(9): 997-1005, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514184
6.
Proteome-wide covalent ligand discovery in native biological systems.
Nature
; 534(7608): 570-4, 2016 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27309814
7.
The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria.
Mar Drugs
; 20(6)2022 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35736176
8.
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase.
Proc Natl Acad Sci U S A
; 116(38): 18808-18814, 2019 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31484779
9.
Metaproteomics Analysis of SARS-CoV-2-Infected Patient Samples Reveals Presence of Potential Coinfecting Microorganisms.
J Proteome Res
; 20(2): 1451-1454, 2021 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33393790
10.
A photoaffinity probe that targets folate-binding proteins.
Bioorg Med Chem Lett
; 40: 127903, 2021 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33713779
11.
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry.
J Am Chem Soc
; 142(25): 10899-10904, 2020 06 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32479075
12.
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs.
Angew Chem Int Ed Engl
; 59(30): 12460-12469, 2020 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32301265
13.
X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors.
Biochemistry
; 58(13): 1728-1737, 2019 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30835452
14.
ComPIL 2.0: An Updated Comprehensive Metaproteomics Database.
J Proteome Res
; 18(2): 616-622, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30525664
15.
A glycal-based photoaffinity probe that enriches sialic acid binding proteins.
Bioorg Med Chem Lett
; 29(18): 2609-2612, 2019 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31387789
16.
Metaproteomics of Colonic Microbiota Unveils Discrete Protein Functions among Colitic Mice and Control Groups.
Proteomics
; 18(3-4)2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29319931
17.
Triflic Acid Treatment Enables LC-MS/MS Analysis of Insoluble Bacterial Biomass.
J Proteome Res
; 17(9): 2978-2986, 2018 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30019906
18.
Expanding the Use of Spectral Libraries in Proteomics.
J Proteome Res
; 17(12): 4051-4060, 2018 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30270626
19.
METLIN: A Technology Platform for Identifying Knowns and Unknowns.
Anal Chem
; 90(5): 3156-3164, 2018 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29381867
20.
Quantitative Metaproteomics and Activity-Based Probe Enrichment Reveals Significant Alterations in Protein Expression from a Mouse Model of Inflammatory Bowel Disease.
J Proteome Res
; 16(2): 1014-1026, 2017 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28052195