Detalhe da pesquisa
1.
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations.
Cell
; 141(7): 1146-58, 2010 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20541250
2.
Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification.
Eur J Neurosci
; 37(12): 1949-61, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23773064
3.
ß2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7.
J Mol Biol
; 432(8): 2633-2650, 2020 04 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32105735
4.
Cd2+, Mn2+, Ni2+ and Se2+ toxicity to Saccharomyces cerevisiae lacking YPK9p the orthologue of human ATP13A2.
Biochem Biophys Res Commun
; 383(2): 198-202, 2009 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19345671
5.
Channeling studies in yeast: yeast as a model for channelopathies?
Neuromolecular Med
; 8(3): 279-306, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16775381
6.
Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification.
Cell Rep
; 12(9): 1430-44, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26299959
7.
pH-dependent localization of Btn1p in the yeast model for Batten disease.
Dis Model Mech
; 4(1): 120-5, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959629
8.
Absence of Btn1p in the yeast model for juvenile Batten disease may cause arginine to become toxic to yeast cells.
Hum Mol Genet
; 16(9): 1007-16, 2007 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17341489