Detalhe da pesquisa
1.
Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease.
Crit Rev Biochem Mol Biol
; 53(3): 279-310, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29718780
2.
Crude extract of Euphorbia formosana induces apoptosis of DU145 human prostate cancer cells acts through the caspase-dependent and independent signaling pathway.
Environ Toxicol
; 31(11): 1600-1611, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26122529
3.
Latex of Euphorbia antiquorum-induced S-phase arrest via active ATM kinase and MAPK pathways in human cervical cancer HeLa cells.
Environ Toxicol
; 30(10): 1205-15, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24706497
4.
Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis.
J Neurochem
; 129(4): 559-72, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24329875
5.
Up-regulation and activation of the P2Y(2) nucleotide receptor mediate neurite extension in IL-1ß-treated mouse primary cortical neurons.
J Neurochem
; 125(6): 885-96, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23550835
6.
Guizhi-Fuling-Wan, a Traditional Chinese Herbal Medicine, Ameliorates Memory Deficits and Neuronal Apoptosis in the Streptozotocin-Induced Hyperglycemic Rodents via the Decrease of Bax/Bcl2 Ratio and Caspase-3 Expression.
Evid Based Complement Alternat Med
; 2012: 656150, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23304209
7.
Green Tea Extract Ameliorates Learning and Memory Deficits in Ischemic Rats via Its Active Component Polyphenol Epigallocatechin-3-gallate by Modulation of Oxidative Stress and Neuroinflammation.
Evid Based Complement Alternat Med
; 2012: 163106, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22919410
8.
Solanum lyratum Extracts Induce Extrinsic and Intrinsic Pathways of Apoptosis in WEHI-3 Murine Leukemia Cells and Inhibit Allograft Tumor.
Evid Based Complement Alternat Med
; 2012: 254960, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22611426
9.
Isoprenoids, small GTPases and Alzheimer's disease.
Biochim Biophys Acta
; 1801(8): 896-905, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20382260
10.
Cholesterol asymmetry in synaptic plasma membranes.
J Neurochem
; 116(5): 684-9, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21214553
11.
Latex of Euphorbia antiquorum induces apoptosis in human cervical cancer cells via c-jun n-terminal kinase activation and reactive oxygen species production.
Nutr Cancer
; 63(8): 1339-47, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22044063
12.
Education partnerships between GRECCs and other VA organizations, Non-VA governmental agencies, academic medical centers, and centers of excellence.
Gerontol Geriatr Educ
; 32(1): 22-37, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21347929
13.
The interaction of beta-amyloid protein with cellular membranes stimulates its own production.
Biochim Biophys Acta
; 1788(5): 964-72, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19366591
14.
A rapid and sensitive assay for determining human brain levels of farnesyl-(FPP) and geranylgeranylpyrophosphate (GGPP) and transferase activities using UHPLC-MS/MS.
Anal Bioanal Chem
; 398(4): 1801-8, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20730526
15.
Quercetin inhibited murine leukemia WEHI-3 cells in vivo and promoted immune response.
Phytother Res
; 24(2): 163-8, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19449452
16.
Interleukin-1beta enhances nucleotide-induced and alpha-secretase-dependent amyloid precursor protein processing in rat primary cortical neurons via up-regulation of the P2Y(2) receptor.
J Neurochem
; 109(5): 1300-10, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19317852
17.
Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients.
Neurobiol Dis
; 35(2): 251-7, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19464372
18.
Ganoderma lucidum extracts inhibited leukemia WEHI-3 cells in BALB/c mice and promoted an immune response in vivo.
Biosci Biotechnol Biochem
; 73(12): 2589-94, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19966494
19.
The effect of propoxycaine.HCl on the physical properties of neuronal membranes.
Chem Phys Lipids
; 154(1): 19-25, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18407836
20.
Isoprenoid quantitation in human brain tissue: a validated HPLC-fluorescence detection method for endogenous farnesyl- (FPP) and geranylgeranylpyrophosphate (GGPP).
Anal Bioanal Chem
; 392(4): 673-80, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18690423