Detalhe da pesquisa
1.
A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Nature
; 522(7556): 315-20, 2015 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085270
2.
Differential control of Toll-like receptor 4-induced interleukin-10 induction in macrophages and B cells reveals a role for p90 ribosomal S6 kinases.
J Biol Chem
; 293(7): 2302-2317, 2018 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229781
3.
Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1.
Bioorg Med Chem Lett
; 28(19): 3255-3259, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30143424
4.
Screening a protein kinase inhibitor library against Plasmodium falciparum.
Malar J
; 16(1): 446, 2017 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29115999
5.
Corrigendum: A novel multiple-stage antimalarial agent that inhibits protein synthesis.
Nature
; 537(7618): 122, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27281209
6.
Identification of small molecule inhibitors of pre-mRNA splicing.
J Biol Chem
; 289(50): 34683-98, 2014 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25281741
7.
Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues.
J Med Chem
; 66(13): 8896-8916, 2023 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37343180
8.
Identification of small molecule inhibitors of pre-mRNA splicing.
J Biol Chem
; 290(10): 6005, 2015 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-25750262
9.
Research Techniques Made Simple: An Introduction to Drug Discovery for Dermatology.
J Invest Dermatol
; 139(11): 2252-2257.e1, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31648685
10.
Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1).
ACS Med Chem Lett
; 10(3): 341-347, 2019 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30891137
11.
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.
J Med Chem
; 62(3): 1180-1202, 2019 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30570265
12.
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines.
Cell Chem Biol
; 24(8): 981-992.e4, 2017 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28781123
13.
Discovery of Inhibitors of Trypanosoma brucei by Phenotypic Screening of a Focused Protein Kinase Library.
ChemMedChem
; 10(11): 1809-20, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26381210
14.
From on-target to off-target activity: identification and optimisation of Trypanosoma brucei GSK3 inhibitors and their characterisation as anti-Trypanosoma brucei drug discovery lead molecules.
ChemMedChem
; 8(7): 1127-37, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23776181
15.
Optimisation of the anti-Trypanosoma brucei activity of the opioid agonist U50488.
ChemMedChem
; 6(10): 1832-40, 2011 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-21834094
16.
Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3.
ChemMedChem
; 6(12): 2214-24, 2011 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-21913331