Detalhe da pesquisa
1.
Structure and dynamics of the staphylococcal pyridoxal 5-phosphate synthase complex reveal transient interactions at the enzyme interface.
J Biol Chem
; : 107404, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38782204
2.
Discovery of Small-Molecule Allosteric Inhibitors of PfATC as Antimalarials.
J Am Chem Soc
; 144(41): 19070-19077, 2022 10 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36195578
3.
Live and Let Dye: Visualizing the Cellular Compartments of the Malaria Parasite Plasmodium falciparum.
Cytometry A
; 97(7): 694-705, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31738009
4.
Insights in Chloroquine Action: Perspectives and Implications in Malaria and COVID-19.
Cytometry A
; 97(9): 872-881, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32686260
5.
Solution Structures and Dynamic Assembly of the 24-Meric Plasmodial Pdx1-Pdx2 Complex.
Int J Mol Sci
; 21(17)2020 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32825141
6.
Melatonin activates FIS1, DYN1, and DYN2 Plasmodium falciparum related-genes for mitochondria fission: Mitoemerald-GFP as a tool to visualize mitochondria structure.
J Pineal Res
; 66(2): e12484, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29480948
7.
Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
Biochem Biophys Res Commun
; 497(3): 835-842, 2018 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29476738
8.
Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles.
Arch Toxicol
; 92(4): 1435-1451, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29356861
9.
Plasmodium falciparum GFP-E-NTPDase expression at the intraerythrocytic stages and its inhibition blocks the development of the human malaria parasite.
Purinergic Signal
; 13(3): 267-277, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28285440
10.
Exploring inhibition of Pdx1, a component of the PLP synthase complex of the human malaria parasite Plasmodium falciparum.
Biochem J
; 449(1): 175-87, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23039077
11.
Enhanced Immunogenicity and Protective Effects against SARS-CoV-2 Following Immunization with a Recombinant RBD-IgG Chimeric Protein.
Vaccines (Basel)
; 12(4)2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675739
12.
High Target Homology Does Not Guarantee Inhibition: Aminothiazoles Emerge as Inhibitors of Plasmodium falciparum.
ACS Infect Dis
; 10(3): 1000-1022, 2024 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38367280
13.
Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 12): 2320-9, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24311574
14.
The antioxidative effect of de novo generated vitamin B6 in Plasmodium falciparum validated by protein interference.
Biochem J
; 443(2): 397-405, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22242896
15.
Natural products as a source for treating neglected parasitic diseases.
Int J Mol Sci
; 14(2): 3395-439, 2013 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-23389040
16.
Plant Extracts as a Source of Natural Products with Potential Antimalarial Effects: An Update from 2018 to 2022.
Pharmaceutics
; 15(6)2023 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37376086
17.
Protein Arginylation Is Regulated during SARS-CoV-2 Infection.
Viruses
; 15(2)2023 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36851505
18.
Virulence Profiles of Wild-Type, P.1 and Delta SARS-CoV-2 Variants in K18-hACE2 Transgenic Mice.
Viruses
; 15(4)2023 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37112979
19.
1,3-Diphenylureido hydroxamate as a promising scaffold for generation of potent antimalarial histone deacetylase inhibitors.
Sci Rep
; 13(1): 21006, 2023 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38030668
20.
Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections.
Commun Biol
; 6(1): 1058, 2023 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37853179