Detalhe da pesquisa
1.
De Novo Discovery of Cysteine Frameworks for Developing Multicyclic Peptide Libraries for Ligand Discovery.
J Am Chem Soc
; 145(51): 28264-28275, 2023 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092662
2.
Disulfide-Directed Multicyclic Peptide Libraries for the Discovery of Peptide Ligands and Drugs.
J Am Chem Soc
; 145(3): 1964-1972, 2023 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36633218
3.
Design and Ribosomal Incorporation of Noncanonical Disulfide-Directing Motifs for the Development of Multicyclic Peptide Libraries.
J Am Chem Soc
; 144(11): 5116-5125, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35289603
4.
Redox-Regulated Conformational Change of Disulfide-Rich Assembling Peptides.
Angew Chem Int Ed Engl
; 61(44): e202212829, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36106963
5.
Fast and Selective Reaction of 2-Benzylacrylaldehyde with 1,2-Aminothiol for Stable N-Terminal Cysteine Modification and Peptide Cyclization.
Bioconjug Chem
; 32(9): 2065-2072, 2021 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34405993
6.
Directed Disulfide Pairing and Folding of Peptides for the De Novo Development of Multicyclic Peptide Libraries.
J Am Chem Soc
; 142(38): 16285-16291, 2020 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32914969
7.
Condensation of 2-((Alkylthio)(aryl)methylene)malononitrile with 1,2-Aminothiol as a Novel Bioorthogonal Reaction for Site-Specific Protein Modification and Peptide Cyclization.
J Am Chem Soc
; 142(11): 5097-5103, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32108479
8.
Biocompatible and Rapid Cyclization of Peptides with 2,4-Difluoro-6-hydroxy-1,3,5-benzenetricarbonitrile for the Development of Cyclic Peptide Libraries.
Bioconjug Chem
; 31(9): 2085-2091, 2020 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32794769
9.
Design and Synthesis of Disulfide-Rich Peptides with Orthogonal Disulfide Pairing Motifs.
J Org Chem
; 85(17): 11475-11481, 2020 09 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32786636
10.
A Doubly-Quenched Fluorescent Probe for Low-Background Detection of Mitochondrial H2O2.
Anal Chem
; 91(10): 6902-6909, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31021600
11.
Ordered and Isomerically Stable Bicyclic Peptide Scaffolds Constrained through Cystine Bridges and Proline Turns.
Chembiochem
; 20(12): 1514-1518, 2019 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770638
12.
Design and Synthesis of Cross-Link-Dense Peptides by Manipulating Regioselective Bisthioether Cross-Linking and Orthogonal Disulfide Pairing.
J Org Chem
; 84(9): 5187-5194, 2019 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30895794
13.
Chemical and Ribosomal Synthesis of Topologically Controlled Bicyclic and Tricyclic Peptide Scaffolds Primed by Selenoether Formation.
Angew Chem Int Ed Engl
; 58(15): 4880-4885, 2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30762292
14.
Plasmon-Enhanced Ultrasensitive Surface Analysis Using Ag Nanoantenna.
Anal Chem
; 90(3): 2018-2022, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29275628
15.
Thioether-Bonded Fluorescent Probes for Deciphering Thiol-Mediated Exchange Reactions on the Cell Surface.
Anal Chem
; 89(1): 937-944, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27976862
16.
Biscysteine-Bearing Peptide Probes To Reveal Extracellular Thiol-Disulfide Exchange Reactions Promoting Cellular Uptake.
Anal Chem
; 89(16): 8501-8508, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28714307
17.
Proteolytic Unlocking of Ultrastable Twin-Acylhydrazone Linkers for Lysosomal Acid-Triggered Release of Anticancer Drugs.
Bioconjug Chem
; 28(10): 2620-2626, 2017 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28922598
18.
Peptide Macrocycles Developed from Precisely Regulated Multiple Cyclization of Unprotected Peptides.
Chemistry
; 23(60): 15150-15155, 2017 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28833777
19.
Tunable accessibility of dye-doped liposomes towards gold nanoparticles for fluorescence sensing of lipopolysaccharide.
Analyst
; 142(7): 1084-1090, 2017 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28265609
20.
A lysosome-locating and acidic pH-activatable fluorescent probe for visualizing endogenous H2O2 in lysosomes.
Analyst
; 142(23): 4522-4528, 2017 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29099141