Association between psoriasis and asthma: a systematic review and bidirectional meta-analysis.

BACKGROUND: The risk of asthma in patients with psoriasis has been identified in previous studies, but the bidirectional association between the two has not been fully explored. METHODS: We thoroughly searched PubMed, Embase, and the Cochrane Library to find relevant observational studies published from the inception of these databases to October 2023. All the risk and bias assessments were analyzed by STATA 16.0. Where the heterogeneity was less than 50%, the fixed effect model was utilized. While where the level of heterogeneity was more than 50%, the random effect model was applied. Moreover, to identify publication bias, a visual funnel chart, and Egger's test were applied. RESULTS: A total of 12,396,911 participants from 16 studies, published between 2011 and 2023 were included in this meta-analysis. We found that psoriasis patients had a higher risk of developing asthma (OR = 1.48, 95%CI 1.28-1.68). Meanwhile, asthma patients also had a higher overall risk of developing psoriasis (OR = 1.33, 95%CI 1.23-1.44). In the subgroup analysis, we found that the type of study, age, and severity of the psoriasis were significant factors in the survey of asthma risk in psoriasis patients. CONCLUSIONS: In the present systematic review and meta-analysis, we found a bidirectional association between psoriasis and asthma with significantly increased risk. As a result, clinicians should make patients aware of the connection between the two, particularly adolescents or patients with moderate to severe psoriasis who need to be informed about the rising likelihood of developing asthma. TRIAL REGISTRATION: Registration number CRD42023390111 .

Dramatically enhanced degradation of recalcitrant organic contaminants in MgO2/Fe(III) Fenton-like system by organic chelating agents.

Herein, the application of organic acids as chelating agent, including citric acid (CA), tartaric acid (TA), oxalic acid (OA) and ethylenediaminetetraacetic acid (EDTA), to enhance the degradation performance of MgO2/Fe(III) system was investigated in the terms of chelating agent dosage, Fe(III) dosage, reaction temperature, initial solution pH and inorganic anion. When the molar ratio of MgO2/Fe(III)/chelating agent was 1 : 0.7 : 0.3, the degradation efficiencies of Rhodamine B (RhB) increased from 6.7% (without chelating agent) to 42.3%, 98.5%, 48.9% and 25.8% within 30 min for CA, TA, OA, and EDTA, respectively. The promotion effect was mainly attributed to the chelation between chelating agents and Fe(III), rather than the acidification of chelating agents. The pseudo-first-order kinetic model well fitted RhB degradation in MgO2/Fe(III)/TA system, and the kinetic rate constant reached up to 0.295 min-1. Hydroxyl radical was confirmed to be the dominant active species to degrade organics in the MgO2/Fe(III)/TA system. Notably, the degradation system could work in a broad pH (3-11) and temperature (5-35 °C) range. Moreover, the MgO2/Fe(III)/TA system can also effectively degrade methylene blue, tetracycline and bisphenol A. This work provided a new, efficient and environmentally-friendly Fenton-like system for stubborn contaminant treatment.

Biomolecule-Assisted Synthesis and Electro-Catalytic Hydrogen Evolution of Flowerlike Nickel Sulfide Nanostructures.

In this paper, flowerlike nickel sulfide materials are synthesized using a facile solution-phase biomolecule-assisted approach in the presence of L-cysteine (an ordinary and cheap amino acid), which turned out to serve as both the sulfur source and the directing molecule in the formation of nickel sulfide nanostructures. The morphology, structure, and phase composition of the assynthesized nickel sulfide products are characterized using scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy and Raman. Moreover, the nickel sulfide materials are investigated as electro catalysts for hydrogen evolution reaction (HER) in strongly alkaline media. The electro catalytic performance of as-prepared nickel sulfide is promising for applications as non-noble-metal HER catalysts with water splitting for hydrogen production.

Highly pure MgO2 nanoparticles as robust solid oxidant for enhanced Fenton-like degradation of organic contaminants.

In typical Fenton/Fenton-like reactions, H2O2 was usually used as an oxidant to degrade organic contaminants. However, liquid H2O2 is unstable, easy to decompose and has high biological toxicity especially at high concentration. Herein, highly pure magnesium peroxide (MgO2) nanoparticles were first synthesized and used instead of H2O2 to degrade organic dyes. The structure and morphology of as-prepared products were confirmed by XRD, SEM, TEM and FTIR techniques. The active oxygen content of MgO2 nanoparticles reached up to 26.93 wt%, suggesting a high purity of the as-prepared sample. The degradation performance of MgO2 nanoparticles towards organic contaminants was systematically investigated in the terms of the molar ratio of Fe3+ to MgO2, the dosage of MgO2, initial solution pH and different organic dyes. The results indicated the as-prepared MgO2 exhibited excellent degradation ability to various types of organic dyes. 10 mg of MgO2 nanoparticles could almost completely degrade 200 mL of 20 mg/L methylene blue (MB) in 30 min with a TOC removal rate of 70.2%. The efficient degradation performance was ascribed to the generation of hydroxyl radicals in the MgO2/Fe3+ system. The pathways of MB degradation were also proposed based on the determination of the reaction intermediates.