Detalhe da pesquisa
1.
Characterization of nucleosome positioning in hepadnaviral covalently closed circular DNA minichromosomes.
J Virol
; 86(18): 10059-69, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22787202
2.
Safety and efficacy of AK0529 in respiratory syncytial virus-infected infant patients: A phase 2 proof-of-concept trial.
Influenza Other Respir Viruses
; 17(7): e13176, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37502622
3.
Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats.
Lab Invest
; 90(12): 1805-16, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20921949
4.
Discovery of novel 1-phenyl-cycloalkane carbamides as potent and selective influenza fusion inhibitors.
Bioorg Med Chem Lett
; 20(12): 3507-10, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20494579
5.
Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model.
Naunyn Schmiedebergs Arch Pharmacol
; 379(2): 163-79, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18773196
6.
Comparison of antiviral resistance across acute and chronic viral infections.
Antiviral Res
; 158: 103-112, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30086337
7.
Design and Synthesis of Orally Bioavailable 4-Methyl Heteroaryldihydropyrimidine Based Hepatitis B Virus (HBV) Capsid Inhibitors.
J Med Chem
; 59(16): 7651-66, 2016 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27458651
8.
Replicon cell culture system as a valuable tool in antiviral drug discovery against hepatitis C virus.
Antivir Chem Chemother
; 16(1): 1-12, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15739617
9.
Identification of a novel aminotetralin class of HDAC6 and HDAC8 selective inhibitors.
J Med Chem
; 57(19): 8026-34, 2014 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25238284
10.
Identification and characterization of multiple TRIM proteins that inhibit hepatitis B virus transcription.
PLoS One
; 8(8): e70001, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23936368
11.
Inhibition of influenza A virus (H1N1) fusion by benzenesulfonamide derivatives targeting viral hemagglutinin.
PLoS One
; 6(12): e29120, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22195002
12.
Design and synthesis of benzenesulfonamide derivatives as potent anti-influenza hemagglutinin inhibitors.
ACS Med Chem Lett
; 2(8): 603-7, 2011 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-24900355
13.
Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure.
Bioorg Med Chem Lett
; 17(1): 63-7, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17049849
14.
Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic study.
Bioorg Med Chem Lett
; 17(7): 1991-5, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17276060
15.
Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase.
Bioorg Med Chem Lett
; 17(6): 1679-83, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17251021
16.
Isothiazoles as active-site inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 17(1): 28-33, 2007 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17049853
17.
Recent patents on nucleoside and nucleotide inhibitors for HCV.
Recent Pat Antiinfect Drug Discov
; 1(3): 323-31, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18221157
18.
Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors.
Bioorg Med Chem Lett
; 16(22): 5888-91, 2006 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16934455
19.
Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase.
Bioorg Chem
; 34(1): 26-38, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16360193
20.
Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors.
Bioorg Med Chem Lett
; 16(21): 5561-6, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16934458