Analysis of multi-scale effects and spatial heterogeneity of environmental factors influencing purse seine tuna fishing activities in the Western and Central Pacific Ocean.

Understanding the spatial fishing activity distribution characteristics is important for the sustainable development of fisheries. Spatial nonstationarity is always present, especially in marine ecosystems. To explore how marine environmental factors affect the fishing effort of tuna purse seine vessels, data from 2015 to 2020 on the fishing activities of these fleets and environmental variables in the Western and Central Pacific Ocean (WCPO) were analyzed. A Generalized Additive Model (GAM), Geographically Weighted Regression model (GWR), and Multi-Scale Geographically Weighted Regression (MGWR) model were applied to explore the drivers of fishing activity and the impacts of environmental factors on spatial heterogeneity. The results indicate that: (1) The MGWR models has the highest prediction accuracy and effectively reflects the spatial heterogeneity and multi-scale effects of environmental factors in a year. (2) Environmental factors exhibit significant multi-scale effects and spatial heterogeneity on the fishing activities of purse seine tuna vessels. Sea floor depth, salinity at 200 m depth and sea surface temperature show the greatest spatial heterogeneity in their impact on fishing activities. (3) Sea surface temperature, distance to port, and primary productivity and salinity at 200 m depth are key variables influencing the fishing activities of purse seine tuna vessels. These findings are expected to provide scientific and effective guidance for fishery management and sustainable development by assessing the spatial variations in fishing activities at multiple scales.

Analysis of the Distribution Characteristics of Jellyfish and Environmental Factors in the Seawater Intake Area of the Haiyang Nuclear Power Plant in China.

In recent years, there have been frequent jellyfish outbreaks in Chinese coastal waters, significantly impacting the structure, functionality, safety, and economy of nuclear power plant cooling water intake and nearby ecosystems. Therefore, this study focuses on jellyfish outbreaks in Chinese coastal waters, particularly near the Shandong Peninsula. By analyzing jellyfish abundance data, a Generalized Additive Model integrating environmental factors reveals that temperature and salinity greatly influence jellyfish density. The results show variations in jellyfish density among years, with higher densities in coastal areas. The model explains 42.2% of the variance, highlighting the positive correlation between temperature (20-26 °C) and jellyfish density, as well as the impact of salinity (27.5-29‱). Additionally, ocean currents play a significant role in nearshore jellyfish aggregation, with a correlation between ocean currents and site coordinates. This study aims to investigate the relationship between jellyfish blooms and environmental factors. The results obtained from the study provide data support for the prevention and control of blockages in nuclear power plant cooling systems, and provide a data basis for the implementation of monitoring measures in nuclear power plants.

Overexpression of CKS2 is associated with a poor prognosis and promotes cell proliferation and invasion in breast cancer.

Growing evidence indicates that cyclin dependent kinases regulatory subunit 2 (CKS2) serves an essential role in the regulation of multiple cellular processes in diverse human cancer types. The present study investigated the contribution of CKS2 to breast cancer (BC) progression. In the present study, CKS2 expression in BC was detected using Oncomine and The Cancer Genome Atlas database. The association between expression levels and clinical features was explored using Kaplan­Meier plotter and the Breast Cancer Gene­Expression Miner Version 4.0 (bc­GenExMiner) online database. In addition, the roles of CKS2 in BC progression were examined. It was identified that CKS2 expression was significantly increased in BC tissues at the mRNA and protein levels. Bc­GenExMiner demonstrated that high CKS2 expression was associated with a positive estrogen receptor status, progesterone receptor status, nodal status and basal­like status. High CKS2 expression was markedly associated with poor overall survival, relapse­free survival, and distant metastasis­free survival in patients with BC. Moreover, functional assays revealed that CKS2 inhibition suppressed cell proliferation and invasion ability in vitro and reduced tumor growth in vivo. Thus, the present findings suggested that CKS2 may act as a potential biomarker and therapeutic target for the treatment of BC.

[Effects of sediment on the early settlement stage of Sargassum horneri on rocky subtidal reefs].

By using sediment trap and suction pump to measure the relative sediment levels across different sites and water depths, and through the in situ measurements of Sargassum horneri density, this paper assessed the relationships between the distribution of S. horneri and the sediment levels and wave exposure on the rocky subtidal platforms around Gouqi Island, China. The laboratory-based experiments were also conducted to test the effects of different sediment levels on the attachment of S. horneri zygote and the survival rate of S. horneri germling after the attachment. S. horneri predominated at the sites with lesser sediment and wave exposure, but less distributed in the sites with high level sediment and wave-exposure. At different water depths, the distribution of S. horneri was negatively correlated with the amount of sediment. A medium dusting (dry mass 10.47 mg x cm(-2), approximate 0.543 mm deep) of sediment on the plate reduced the percentage of S. horneri zygotes attached to the substratum by 4.4%, and a heavy dusting (dry mass 13.96 mg x cm(-2), approximate 0.724 mm deep) of sediment on the plate completely prevented the attachment. One week after the settlement of the zygotes, there were 24% of the germlings still survived when the dry mass sediment coverage was 13.96 mg x cm(-2). However, when the dry mass sediment coverage was up to 34.9 mg x cm(-2) (approximate 1.81 mm deep), 100% of the germlings died. Overall, the distribution of S. horneri was not only related to sediment level, but also restricted by wave exposure to some extent. Sediment level was a critical factor affecting the distribution of S. horneri, particularly at its zygote attachment stage.