Detalhe da pesquisa
1.
HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα.
Mol Cell
; 55(1): 31-46, 2014 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24882211
2.
The GTPase KRAS suppresses the p53 tumor suppressor by activating the NRF2-regulated antioxidant defense system in cancer cells.
J Biol Chem
; 295(10): 3055-3063, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32001619
3.
HDAC6 regulates DNA damage response via deacetylating MLH1.
J Biol Chem
; 294(15): 5813-5826, 2019 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30770470
4.
Histone deacetylase 6 (HDAC6) deacetylates extracellular signal-regulated kinase 1 (ERK1) and thereby stimulates ERK1 activity.
J Biol Chem
; 293(6): 1976-1993, 2018 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29259132
5.
Ubiquitin-specific Peptidase 10 (USP10) Deubiquitinates and Stabilizes MutS Homolog 2 (MSH2) to Regulate Cellular Sensitivity to DNA Damage.
J Biol Chem
; 291(20): 10783-91, 2016 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26975374
6.
Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2.
J Biol Chem
; 290(37): 22795-804, 2015 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26221039
7.
Extracellular signal-regulated kinase (ERK) phosphorylates histone deacetylase 6 (HDAC6) at serine 1035 to stimulate cell migration.
J Biol Chem
; 288(46): 33156-70, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24089523
8.
Driving effect of P16 methylation on telomerase reverse transcriptase-mediated immortalization and transformation of normal human fibroblasts.
Chin Med J (Engl)
; 2024 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38420748
9.
C-terminal in Sp1-like artificial zinc-finger proteins plays crucial roles in determining their DNA binding affinity.
BMC Biotechnol
; 13: 106, 2013 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24289163
10.
The CMG helicase and cancer: a tumor "engine" and weakness with missing mutations.
Oncogene
; 42(7): 473-490, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36522488
11.
Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function.
Res Sq
; 2023 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37609279
12.
Modeling phenotypic heterogeneity towards evolutionarily inspired osteosarcoma therapy.
Sci Rep
; 13(1): 20125, 2023 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37978271
13.
Global Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer.
Clin Cancer Res
; 27(14): 4012-4024, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33879459
14.
Methylation status of individual CpG sites within Alu elements in the human genome and Alu hypomethylation in gastric carcinomas.
BMC Cancer
; 10: 44, 2010 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20163738
15.
HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1.
Cells
; 9(10)2020 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33020410
16.
The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.
Cell Death Dis
; 11(5): 328, 2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32382008
17.
Dual Farnesyl and Geranylgeranyl Transferase Inhibitor Thwarts Mutant KRAS-Driven Patient-Derived Pancreatic Tumors.
Clin Cancer Res
; 25(19): 5984-5996, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31227505
18.
GSK3 suppression upregulates ß-catenin and c-Myc to abrogate KRas-dependent tumors.
Nat Commun
; 9(1): 5154, 2018 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514931
19.
Binding of Released Bim to Mcl-1 is a Mechanism of Intrinsic Resistance to ABT-199 which can be Overcome by Combination with Daunorubicin or Cytarabine in AML Cells.
Clin Cancer Res
; 22(17): 4440-51, 2016 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27103402
20.
HDAC6-Dependent Functions in Tumor Cells: Crossroad with the MAPK Pathways.
Crit Rev Oncog
; 20(1-2): 65-81, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25746105