Detalhe da pesquisa
1.
Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains.
Cell
; 155(5): 1049-1060, 2013 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24267890
2.
Cell-free formation of RNA granules: bound RNAs identify features and components of cellular assemblies.
Cell
; 149(4): 768-79, 2012 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22579282
3.
Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels.
Cell
; 149(4): 753-67, 2012 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22579281
4.
Discovery of a proneurogenic, neuroprotective chemical.
Cell
; 142(1): 39-51, 2010 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20603013
5.
Targeting HIF2α-ARNT hetero-dimerisation as a novel therapeutic strategy for pulmonary arterial hypertension.
Eur Respir J
; 57(3)2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32972983
6.
Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Cell Chem Biol
; 31(1): 139-149.e14, 2024 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37967558
7.
Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.
bioRxiv
; 2023 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36865268
8.
Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.
Cell Chem Biol
; 30(11): 1453-1467.e8, 2023 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607550
9.
3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma.
J Med Chem
; 62(15): 6876-6893, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31282155
10.
Design and Activity of Specific Hypoxia-Inducible Factor-2α (HIF-2α) Inhibitors for the Treatment of Clear Cell Renal Cell Carcinoma: Discovery of Clinical Candidate ( S)-3-((2,2-Difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1 H-inden-4-yl)oxy)-5-fluorobenzonitrile (PT2385).
J Med Chem
; 61(21): 9691-9721, 2018 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30289716
11.
Bcr-Abl-mediated suppression of normal hematopoiesis in leukemia.
Oncogene
; 24(20): 3246-56, 2005 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-15735695
12.
Inhibition of the Bcr-Abl oncoprotein by Bcr requires phosphoserine 354.
Cancer Res
; 62(2): 386-90, 2002 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11809685
13.
A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma.
Cancer Res
; 76(18): 5491-500, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27635045
14.
Jak2 is involved in c-Myc induction by Bcr-Abl.
Oncogene
; 21(47): 7137-46, 2002 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12370803
15.
Mitochondrial phosphoproteome revealed by an improved IMAC method and MS/MS/MS.
Mol Cell Proteomics
; 6(4): 669-76, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17208939