The acute effect of roller massager on knee joint range of motion and muscle pain in older adults with total knee arthroplasty.

OBJECTIVES: Older adults with total knee arthroplasty (TKA) have a limited range of knee joint motion due to pain and stiffness. A roller massager (RM) has recently been suggested to decrease pain and increase joint range of motion (ROM). Therefore, this study aimed to investigate the acute effect of RM intervention on pain and knee joint ROM in older adults with TKA in the second postoperative week. METHODS: The participants were 23 patients (76.3±5.4 years) who had undergone TKA for knee OA. The degree of pain during the ROM measurements was measured using the visual analog scale before and immediately after the RM intervention. The RM intervention was performed on the thigh's lateral, central, and medial parts for three sets of 60 s using an RM. RESULTS: RM intervention could significantly increase knee flexion ROM (p<0.01, d=0.41, Δchange: 4.1±3.2°) and decrease pain during the knee ROM measurements (p<0.01, d=-0.53, Δchange: -11.9±21.0). CONCLUSIONS: The three sets of 60-s RM intervention significantly increased knee flexion ROM and reduced pain in older adults with TKA in the second postoperative week. These results show that RM intervention is an effective tool for treating stiffness and pain after TKA.

Theoretical concentration limit and maximum annual optical efficiency of static/low-concentration CPV for horizontal integration to vehicle bodies.

This study proposes an extended theoretical formula to characterize the relationship between the geometrical concentration ratio Cg and arbitrary incidence-angle range to objectively understand the theoretical limit performance of vehicle-integrated concentrator photovoltaics (VICPVs), i.e., static and low-concentration CPVs installed on a horizontal surface. Theoretical analysis revealed that the maximum annual optical efficiency (maximum annual solar energy yield) can be achieved by selectively collecting the sunlight incident only from a specific incidence-angle range of θ1-θ2 (θ1 ≠ 0°), regardless of the geographical location, which is associated with the angular distribution of the annual solar energy on the concentrator aperture. Moreover, the results of the solar concentrator design based on the obtained formula clarified that the annual optical efficiencies of the optical systems with aspheric lens or dielectric-filled crossed compound-parabolic-concentrator lens were 64-89% of the theoretical limit depending on the location for Cg = 3.5×. Nevertheless, the concentrator design can be further improved for practical applications.

Optical design and demonstration of microtracking CPV module with bi-convex aspheric lens array.

A microtracking concentrator photovoltaics (CPV) module with a bi-convex aspheric lens array was designed, and its performance was numerically and experimentally verified. The lens shape was optimized considering the yearly incidence characteristics of direct solar radiation. The lens optimized at 127 × was found to converge 68.7% of the yearly cumulative direct solar radiation to solar cells and to be robust against changes in installation azimuth and tilt angles. The incidence-angle characteristics of a prototype lens agreed well with the design analysis. In an outdoor test using a prototype microtracking CPV module with an optimized lens and a triple-junction solar cell, the power generation was 1.32 times higher than that of the 17%-efficient Si cell and nearly 30% module conversion efficiency was achieved under clear sky conditions.

Light trapping for photovoltaic cells using polarization-insensitive angle-selective filters under monochromatic illumination.

We have proposed a light-trapping concept for photovoltaic (PV) cells under monochromatic illumination with restricted incident angles. We employed a configuration consisting of a shortpass filter (SPF) on the front surface and a diffuse reflector on the rear surface of the cell. The SPF was designed so that it functioned as a polarization-insensitive angle-selective filter. We fabricated 30-80-µm-thick crystalline silicon samples for incident angles changing within 30°, and analyzed the measured results using a ray-trace simulation with the Monte Carlo method. The ratio of the absorbed intensity to the 1064 nm illumination intensity was 0.69-0.85, which was higher than those equipped with antireflection coatings instead of the SPFs by 0.19-0.13. Thus, we have proven the light-trapping concept of the SPF/diffuse reflector configuration for monochromatic illumination. The PV cells could be applied to wireless power supply, in particular from solar-pumped lasers.

Experimental measurements of a prototype high concentration Fresnel lens CPV module for the harvesting of diffuse solar radiation.

A prototype concentrator photovoltaic (CPV) module with high solar concentration, an added low-cost solar cell, and an adjoining multi-junction solar cell is fabricated and experimentally demonstrated. In the present CPV module, the low cost solar cell captures diffuse solar radiation penetrating the concentrator lens and the multi-junction cell captures concentrated direct solar radiation. On-sun test results show that the electricity generated by a Fresnel lens-based CPV module with an additional crystalline silicon solar cell is greater than that for a conventional CPV module by a factor of 1.44 when the mean ratio of diffuse normal irradiation to global normal irradiation at the module aperture is 0.4. Several fundamental optical characteristics are presented for the present module.

Characterization of light absorption in thin-film silicon with periodic nanohole arrays.

Light absorption in thin-film nanostructured monocrystalline silicon (c-Si) in a glass/Ag(0.2 µm)/c-Si(1 µm) stack is characterized using simulations and measurements. Nanohole (NH) arrays designed for a practical thin-film solar cell configuration experimentally exhibit a significant improvement of the light absorption in the 1-µm ultrathin c-Si layer that exceeds the theoretical Yablonovitch limit in the long wavelength range. Fabricated square-lattice and hexagonal NH arrays give relative improvements of 65 and 70%, respectively, in the total absorption compared to a nonpatterned stack. The effect of an indium-tin-oxide (ITO) coating is also simulated, and an empty NH configuration gives the lowest ITO parasitic absorption.

Two kinesin-like proteins mediate actin-based chloroplast movement in Arabidopsis thaliana.

Organelle movement is essential for efficient cellular function in eukaryotes. Chloroplast photorelocation movement is important for plant survival as well as for efficient photosynthesis. Chloroplast movement generally is actin dependent and mediated by blue light receptor phototropins. In Arabidopsis thaliana, phototropins mediate chloroplast movement by regulating short actin filaments on chloroplasts (cp-actin filaments), and the chloroplast outer envelope protein CHUP1 is necessary for cp-actin filament accumulation. However, other factors involved in cp-actin filament regulation during chloroplast movement remain to be determined. Here, we report that two kinesin-like proteins, KAC1 and KAC2, are essential for chloroplasts to move and anchor to the plasma membrane. A kac1 mutant showed severely impaired chloroplast accumulation and slow avoidance movement. A kac1kac2 double mutant completely lacked chloroplast photorelocation movement and showed detachment of chloroplasts from the plasma membrane. KAC motor domains are similar to those of the kinesin-14 subfamily (such as Ncd and Kar3) but do not have detectable microtubule-binding activity. The C-terminal domain of KAC1 could interact with F-actin in vitro. Instead of regulating microtubules, KAC proteins mediate chloroplast movement via cp-actin filaments. We conclude that plants have evolved a unique mechanism to regulate actin-based organelle movement using kinesin-like proteins.

Postoperative anemia following posterior decompression surgery for lumbar spinal canal stenosis.

The incidence of lumbar spinal canal stenosis (LSCS) is increasing in Japan. Posterior lumbar decompression surgery, wide fenestration and laminectomy, for LSCS is a common treatment modality. Compared with posterior fusion surgery, posterior decompression surgery has been considered as less invasive. However, no reports regarding postoperative anemia following posterior decompression surgery have been published. In this retrospective study, we evaluated changes in hemoglobin values following wide fenestration in 80 patients with LSCS based on the number of operated levels, and also analyzed the differences between intraoperative and postoperative bleeding volume. Two patients required allogenic transfusion. The mean preoperative hemoglobin values were 13.6 g/dL and the mean postoperative minimum hemoglobin values were 11.2 g/dL. The mean hemoglobin values decreased by 1.8 g/dL in patients with one operated level (n = 15); 2.2 g/dL in those with two operated levels (n = 31); 2.6 g/dL in those with three operated levels (n = 23); and 3 g/dL in those with four operated levels (n = 11). The mean decrease in hemoglobin values was calculated as follows: 1.8 + 0.4 × (X - 1), where X was the number of operated levels. The mean intraoperative bleeding volume was 94 ml and the mean postoperative bleeding volume was 418 ml. Postoperative bleeding volume was significantly larger than intraoperative bleeding volume. Accordingly, postoperative hemoglobin values can be predicted in patients undergoing wide fenestration. Effective management of postoperative bleeding is necessary to prevent postoperative anemia.

A 1-Week Comprehensive Foam Rolling Intervention Program Can Improve Knee Pain but Not Muscle Function and Range of Motion in Patients with Total Knee Arthroplasty.

We investigate the effect of a 1-week comprehensive foam rolling (FR) intervention program on knee pain, range of motion (ROM), and muscle function in patients with TKA.Thirty patients with TKA were randomly allocated to FR (n = 15) or control (n = 15) groups. The control group received only regular physical therapy. Patients in the FR group performed the FR intervention in addition to their regular physical therapy twice daily from postoperative weeks two to three (60 s × 3 repetitions × 2 times/day × 6 days: total = 2160 s). Pain score, knee flexion and extension ROM, muscle strength, walking function, and balance function were measured before and after the FR intervention. From the second to third postoperative weeks, there were significant improvements in all variables, and the reduction in pain score at stretching was significantly greater in the FR group (-26.0 ± 1.4; p < 0.05) than in the control group (-12.5 ± 1.9). However, there was no significant difference in changes in the other variables except for the pain score at stretching between FR and control groups. A 1-week comprehensive FR intervention program in patients with TKA could reduce pain scores at stretching without a synergistic effect on physical function, i.e., walking speed, balance function, and muscle strength of the knee extensors muscles.

From local structure to nanosecond recrystallization dynamics in AgInSbTe phase-change materials.

Phase-change optical memories are based on the astonishingly rapid nanosecond-scale crystallization of nanosized amorphous 'marks' in a polycrystalline layer. Models of crystallization exist for the commercially used phase-change alloy Ge(2)Sb(2)Te(5) (GST), but not for the equally important class of Sb-Te-based alloys. We have combined X-ray diffraction, extended X-ray absorption fine structure and hard X-ray photoelectron spectroscopy experiments with density functional simulations to determine the crystalline and amorphous structures of Ag(3.5)In(3.8)Sb(75.0)Te(17.7) (AIST) and how they differ from GST. The structure of amorphous (a-) AIST shows a range of atomic ring sizes, whereas a-GST shows mainly small rings and cavities. The local environment of Sb in both forms of AIST is a distorted 3+3 octahedron. These structures suggest a bond-interchange model, where a sequence of small displacements of Sb atoms accompanied by interchanges of short and long bonds is the origin of the rapid crystallization of a-AIST. It differs profoundly from crystallization in a-GST.

Structural transformation of Sb-based high-speed phase-change material.

The crystal structure of a phase-change recording material (the compound Ag(3.4)In(3.7)Sb(76.4)Te(16.5)) enclosed in a vacuum capillary tube was investigated at various temperatures in a heating process using a large Debye-Scherrer camera installed in BL02B2 at SPring-8. The amorphous phase of this material turns into a crystalline phase at around 416 K; this crystalline phase has an A7-type structure with atoms of Ag, In, Sb or Te randomly occupying the 6c site in the space group. This structure was maintained up to around 545 K as a single phase, although thermal expansion of the crystal lattice was observed. However, above this temperature, phase separation into AgInTe(2) and Sb-Te transpired. The first fragment, AgInTe(2), reliably maintained its crystal structure up to the melting temperature. On the other hand, the atomic configuration of the Sb-Te gradually varied with increasing temperature. This gradual structural transformation can be described as a continuous growth of the modulation period γ.

Short actin-based mechanism for light-directed chloroplast movement in Arabidopsis.

Organelle movement is essential for proper function of living cells. In plants, these movements generally depend on actin filaments, but the underlying mechanism is unknown. Here, in Arabidopsis, we identify associations of short actin filaments along the chloroplast periphery on the plasma membrane side associated with chloroplast photorelocation and anchoring to the plasma membrane. We have termed these chloroplast-actin filaments (cp-actin filaments). Cp-actin filaments emerge from the chloroplast edge and exhibit rapid turnover. The presence of cp-actin filaments depends on an actin-binding protein, chloroplast unusual positioning1 (CHUP1), localized on the chloroplast envelope. chup1 mutant lacked cp-actin filaments but showed normal cytoplasmic actin filaments. When irradiated with blue light to induce chloroplast movement, cp-actin filaments relocalize to the leading edge of chloroplasts before and during photorelocation and are regulated by 2 phototropins, phot1 and phot2. Our findings suggest that plants evolved a unique actin-based mechanism for organelle movement.

Red light, Phot1 and JAC1 modulate Phot2-dependent reorganization of chloroplast actin filaments and chloroplast avoidance movement.

The phototropin (phot)-dependent intracellular relocation of chloroplasts is a ubiquitous phenomenon in plants. We have previously revealed the involvement of a short cp-actin (chloroplast actin) filament-based mechanism in this movement. Here, the reorganization of cp-actin filaments during the avoidance movement of chloroplasts was analyzed in higher time resolution under blue GFP (green fluorescent protein) excitation light in an actin filament-visualized line of Arabidopsis thaliana. Under standard background red light of 89 µmol m(-2) s(-1), cp-actin filaments transiently disappeared at approximately 30 s and reappeared in a biased configuration on chloroplasts approximately 70 s after blue excitation light irradiation. The timing of biased cp-actin reappearance was delayed under the background of strong red light or in the absence of red light. Consistently, chloroplast movement was delayed under these conditions. In phot1 mutants, acceleration of both the disappearance and reappearance of cp-actin filaments occurred, indicating an inhibitory action of phot1 on reorganization of cp-actin filaments. Avoidance movements began sooner in phot1 than in wild-type plants. No reorganization of cp-actin filaments was seen in phot2 or phot1phot2 mutants lacking phot2, which is responsible for avoidance movements. Surprisingly, jac1 (j-domain protein required for chloroplast accumulation response 1) mutants, lacking the accumulation response, showed no avoidance movements under the whole-cell irradiation condition for GFP observation. Cp-actin filaments in jac1 did not show a biased distribution, with a small or almost no transient decrease in the number. These results indicate a close association between the biased distribution of cp-actin filaments and chloroplast movement. Further, JAC1 is suggested to function in the biased cp-actin filament distribution by regulating their appearance and disappearance.

Design of wavelength selective concentrator for micro PV/TPV systems using evolutionary algorithm.

This paper describes the results of exploring photonic structures that behave as wavelength selective concentrators (WSCs) of solar/thermal radiation. An evolutionary algorithm was combined with the finite-difference time-domain method (EA-FDTD) to determine the optimum photonic structure that can concentrate a designated wavelength range of beam solar radiation and diffusive thermal radiation in such a manner that the range matches the photosensitivity of micro photovoltaic and thermophotovoltaic cells. Our EA-FDTD method successfully generated a photonic structure capable of performing wavelength selective concentration close to the theoretical limit. Our WSC design concept can be successfully extended to three-dimensional structures to further enhance efficiency.

Performance of see-through prism CPV module for window integrated photovoltaics.

We have examined the performance of a see-through photovoltaics module that uses a low-concentration prism concentrator by undertaking ray-tracing analysis and an on-site experiment. The incident angle dependency of the prism concentrator makes it possible to concentrate direct solar radiation onto solar cells and transmit diffuse solar radiation. Fewer solar cells can then be used without sacrificing the conversion efficiency or lighting performance. The module generates approximately 1.15 more electricity than a conventional module while operating with 63% less solar cell area. We also introduce a design method for the concentrator geometry that adjusts the incident angle dependency for different latitude and tilt angles.

Characterization of antireflection moth-eye film on crystalline silicon photovoltaic module.

We have characterized antireflection (AR) moth-eye films placed on top of crystalline silicon photovoltaic (PV) modules by indoor and outdoor experiments and examined improvements in conversion efficiency. The effects of the ratio of diffuse solar irradiation to total solar irradiation (diffusion index) and incident angle on efficiency have been quantitatively analyzed. Using computer simulations, yearly efficiency improvements under different installation conditions have been projected. We have shown that the use of AR moth-eye films offers the best advantages. Further, vertical tilt angle installation leads to the highest efficiency improvement, whereas spectral matching with the PV modules influences the efficiency improvement.

Crystallization of the chalcogenide compound Sb8Te3.

The crystallization of a sputtered Sb(8)Te(3) film was examined in an X-ray powder diffraction experiment. An as-sputtered, amorphous Sb(8)Te(3) film crystallized during heating into a structure of Sb-Te homologous series modulated along the stacking direction. During heating the lattice parameters and the modulation period γ were found to change significantly and continuously; this observation suggests a continuous change in the stacking sequence. A superspace analysis revealed that with heating the modulation period γ increased to a value that seemed to be determined by the atomic composition. Once γ reached this value it remained unchanged with cooling. A three-dimensional projection of the converged four-dimensional superspace structure corresponded to the homologous Sb(8)Te(3) structure.

Structural investigation of GeSb6Te10 and GeBi6Te10 intermetallic compounds in the chalcogenide homologous series.

The crystal structures of GeSb(6)Te(10) and GeBi(6)Te(10) were scrutinized using an X-ray powder diffraction method, which revealed that these compounds crystallize in trigonally distorted cubic close-packed structures with a 51-layer period (R3m). Each layer consists of a triangular atomic net; Te atoms occupy their own specific layers, whereas Ge, Sb and Bi atoms are located in the other layers. In these pseudobinary compounds, random atomic occupations of Ge and Sb/Bi are observed and the layers form two kinds of elemental structural blocks by their successive stacking along the c axis. These compounds can be presumed to be isostructural. It is known that the chemical formula of the chalcogenide compounds with the homologous structures found in these pseudobinary systems can be written as (GeTe)(n)(Sb(2)Te(3))(m) or (GeTe)(n)(Bi(2)Te(3))(m) (n, m: integer); the GeSb(6)Te(10) and GeBi(6)Te(10) investigated in this study, which correspond to the case in which n = 1 and m = 3, naturally have 3 x l = 51-layer structures according to a formation rule l = 2n + 5m commonly found in the compounds of these chalcogenide systems (l represents the number of layers in the basic structural unit). Calculations based on the density functional theory revealed that these materials are compound semiconductors with very narrow band gaps.

Large Malignant Fibrous Histiocytoma Treated with Hypofractionated Proton Beam Therapy and Local Hyperthermia.

PURPOSE: Malignant fibrous histiocytoma (MFH) is one of the most common soft tissue sarcomas. The standard treatment is adequate surgical resection; in addition, radiation therapy plays a major role in perioperative treatment in most cases. Herein, we report the case of a patient with a large MFH who was successfully treated with combined proton beam therapy (PBT) and local hyperthermia (LH). CASE PRESENTATION: A 60-year-old man presented with a 6×4-cm mass on his left thigh. Histopathology and immunohistochemistry indicated MFH, and he refused limb amputation. He received treatment with PBT at a dose at 72 GyE in 18 fractions. To cover the entire large target lesion, we used a patch-field protocol. He also concurrently received 7 courses of LH. The combination therapy achieved long-term local control without severe acute or late toxicity during the 7-year follow-up period. CONCLUSIONS: This case suggests that the combination of PBT and LH may be an option as a limb-preserving treatment for large inoperable MFH in the extremities.

System of laser pump and synchrotron radiation probe microdiffraction to investigate optical recording process.

We have developed a system of laser-pump and synchrotron radiation probe microdiffraction to investigate the phase-change process on a nanosecond time scale of Ge2Sb2Te5 film embedded in multi-layer structures, which corresponds to real optical recording media. The measurements were achieved by combining (i) the pump-laser system with a pulse width of 300 ps, (ii) a highly brilliant focused microbeam with wide peak-energy width (ΔE∕E ~ 2%) made by focusing helical undulator radiation without monochromatization, and (iii) a precise sample rotation stage to make repetitive measurements. We successfully detected a very weak time-resolved diffraction signal by using this system from 100-nm-thick Ge2Sb2Te5 phase-change layers. This enabled us to find the dependence of the crystal-amorphous phase change process of the Ge2Sb2Te5 layers on laser power.