Detalhe da pesquisa
1.
Interleukin-6 Drives Mitochondrial Dysregulation and Accelerates Physical Decline: Insights From an Inducible Humanized IL-6 Knock-In Mouse Model.
J Gerontol A Biol Sci Med Sci
; 78(10): 1740-1752, 2023 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37310873
2.
Metabolomics-Based Identification of Metabolic Dysfunction in Frailty.
J Gerontol A Biol Sci Med Sci
; 77(12): 2367-2372, 2022 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36580380
3.
Serum Concentrations of Losartan Metabolites Correlate With Improved Physical Function in a Pilot Study of Prefrail Older Adults.
J Gerontol A Biol Sci Med Sci
; 77(12): 2356-2366, 2022 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35511890
4.
Targeted Deletion of Interleukin-6 in a Mouse Model of Chronic Inflammation Demonstrates Opposing Roles in Aging: Benefit and Harm.
J Gerontol A Biol Sci Med Sci
; 76(2): 211-215, 2021 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32585682
5.
Plasma levels of corticosterone, tumor necrosis factor receptor 1 and interleukin 6 are influenced by age, sex and chronic inflammation in mice treated with acute temperature stress.
Exp Gerontol
; 142: 111136, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33164891
6.
Frailty transitions, inflammation, and mortality among persons aging with HIV infection and injection drug use.
AIDS
; 34(8): 1217-1225, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32287069
7.
Kynurenines link chronic inflammation to functional decline and physical frailty.
JCI Insight
; 5(16)2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32814718
8.
Upregulated ex vivo expression of stress-responsive inflammatory pathway genes by LPS-challenged CD14(+) monocytes in frail older adults.
Mech Ageing Dev
; 130(3): 161-6, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19027777
9.
Upregulated monocytic expression of CXC chemokine ligand 10 (CXCL-10) and its relationship with serum interleukin-6 levels in the syndrome of frailty.
Cytokine
; 46(3): 319-24, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19342252
10.
The physical and biological characterization of a frail mouse model.
J Gerontol A Biol Sci Med Sci
; 63(4): 391-8, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18426963
11.
Impaired mitochondrial degradation by autophagy in the skeletal muscle of the aged female interleukin 10 null mouse.
Exp Gerontol
; 73: 23-7, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26596403
12.
Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats.
Aging (Albany NY)
; 8(4): 769-76, 2016 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26997106
13.
Skeletal muscle ATP kinetics are impaired in frail mice.
Age (Dordr)
; 36(1): 21-30, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23695949
14.
Losartan improves measures of activity, inflammation, and oxidative stress in older mice.
Exp Gerontol
; 58: 174-8, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25077714
15.
Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults.
J Gerontol A Biol Sci Med Sci
; 69(2): 165-73, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23689826
16.
Inflammation and mortality in a frail mouse model.
Age (Dordr)
; 34(3): 705-15, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21633802
17.
Decreased cell proliferation and altered cytokine production in frail older adults.
Aging Clin Exp Res
; 16(3): 249-52, 2004 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-15462470