Detalhe da pesquisa
1.
Adjustment of the area under the concentration curve by terminal rate constant for bioequivalence assessment in a parallel-group study of lamotrigine.
Br J Clin Pharmacol
; 85(3): 563-569, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30511473
2.
Anti-IL-7 receptor α monoclonal antibody (GSK2618960) in healthy subjects - a randomized, double-blind, placebo-controlled study.
Br J Clin Pharmacol
; 85(2): 304-315, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30161291
3.
Model-based Evaluation of the Clinical and Microbiological Efficacy of Vancomycin: A Prospective Study of Chinese Adult In-house Patients.
Clin Infect Dis
; 67(suppl_2): S256-S262, 2018 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30423042
4.
Increased oral AUC of baicalin in streptozotocin-induced diabetic rats due to the increased activity of intestinal beta-glucuronidase.
Planta Med
; 76(1): 70-5, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19639536
5.
[Near infrared reflectance spectroscopy (NIRS) and its application in the determination for the quality of animal feed and products].
Guang Pu Xue Yu Guang Pu Fen Xi
; 30(6): 1482-7, 2010 Jun.
Artigo
em Chinês
| MEDLINE | ID: mdl-20707134
6.
[Rapid evaluation of beef quality by NIRS technology].
Guang Pu Xue Yu Guang Pu Fen Xi
; 30(3): 685-7, 2010 Mar.
Artigo
em Chinês
| MEDLINE | ID: mdl-20496687
7.
Cytochrome p450 turnover: regulation of synthesis and degradation, methods for determining rates, and implications for the prediction of drug interactions.
Curr Drug Metab
; 9(5): 384-94, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18537575
8.
The consequences of 3,4-methylenedioxymethamphetamine induced CYP2D6 inhibition in humans.
J Clin Psychopharmacol
; 28(5): 523-9, 2008 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-18794647
9.
Prediction of intestinal first-pass drug metabolism.
Curr Drug Metab
; 8(7): 676-84, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17979655
10.
Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats.
Neuropharmacology
; 53(5): 657-63, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17845805
11.
Theoretical assessment of a new experimental protocol for determining kinetic values describing mechanism (time)-based enzyme inhibition.
Eur J Pharm Sci
; 31(3-4): 232-41, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17512176
12.
The Constraints, Construction, and Verification of a Strain-Specific Physiologically Based Pharmacokinetic Rat Model.
J Pharm Sci
; 106(9): 2826-2838, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28495566
13.
Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA.
J Psychopharmacol
; 20(6): 842-9, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16714321
14.
The impact of experimental design on assessing mechanism-based inactivation of CYP2D6 by MDMA (Ecstasy).
J Psychopharmacol
; 20(6): 834-41, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16478752
15.
Kinetic values for mechanism-based enzyme inhibition: assessing the bias introduced by the conventional experimental protocol.
Eur J Pharm Sci
; 26(3-4): 334-40, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16137870
16.
Effect of tamsulosin on the pharmacokinetics of dutasteride in Chinese male healthy volunteers.
Clin Pharmacol Drug Dev
; 4(6): 427-33, 2015 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27137714
17.
The effects of dose staggering on metabolic drug-drug interactions.
Eur J Pharm Sci
; 20(2): 223-32, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14550889
18.
Safety, pharmacokinetics, pharmacodynamics, and bioavailability of GSK2018682, a sphingosine-1-phosphate receptor modulator, in healthy volunteers.
Clin Pharmacol Drug Dev
; 3(3): 170-8, 2014 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27128606
19.
Physiologically-based Kinetic Modelling (PBK Modelling): meeting the 3Rs agenda. The report and recommendations of ECVAM Workshop 63.
Altern Lab Anim
; 35(6): 661-71, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18186671
20.
Discovery of novel 1,2,4-thiadiazole derivatives as potent, orally active agonists of sphingosine 1-phosphate receptor subtype 1 (S1P(1)).
J Med Chem
; 55(9): 4286-96, 2012 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22500954