RESUMO
BACKGROUNDS OBJECTIVES: Recent research in Cameroon reported several occurrences of dengue in urban settings, but concurrent dengue-malaria infection has received less attention, particularly in the East region. METHODS: A two-month cross-sectional and comparative research was performed at Bertoua Regional Hospital which included 50 malaria-positive participants and 90 non-malaria subjects. Participants were selected and provided with a questionnaire to collect sociodemographic data. Blood samples were collected and tested for dengue infection and hematological parameters were assessed. RESULTS: Dengue fever was found in 14% of malarial patients vs 66.66% of controls. Secondary dengue infection was more prevalent in malarial patients than in non-malarial patients. Gender, age, and place of residence were positively correlated to dengue seropositivity. Platelets were substantially lower (P<0.001) in the malarial group than in the non-malarial group. INTERPRETATION CONCLUSION: In the study, coinfected patients were found to be more vulnerable to dengue, emphasizing the importance of epidemiological surveillance.
Assuntos
Coinfecção , Dengue , Hospitais Públicos , Malária , Humanos , Dengue/epidemiologia , Dengue/complicações , Masculino , Feminino , Camarões/epidemiologia , Adulto , Estudos Transversais , Estudos Soroepidemiológicos , Coinfecção/epidemiologia , Adulto Jovem , Pessoa de Meia-Idade , Malária/epidemiologia , Malária/complicações , Adolescente , Criança , Idoso , Inquéritos e QuestionáriosRESUMO
In this study raw and steamed Pleurotus ostreatus were dried and ground and fractionated by sieving into four granulometric classes (< 200 µm, 200-250 µm, 250-355 µm and > 355 µm) and unsieved powders. The combined steam cooking and sieving improved the content of total polyphenols (+ 59.45%), flavonoids (+ 76.47%), condensed tannins (+ 68.75%) and trace elements (+ 45.51% Fe, + 63.63% Cu, + 62.42% Mn, + 121.11% Zn, and + 53.52% Se) as well as in-vitro and in-vivo antioxidant activities in the finest fraction < 200 µm compared to the raw powder. It was found that the intake at a dose of 250 mg/kg body weight of the finest fractions of raw and steamed powders by the stressed rats had more of a hepatoprotective effect marked by a reduction in the level of transaminases ALAT and ASAT. This work opens a new approach for valuing edible mushrooms in the development of new food products with high antioxidant value.