Detalhe da pesquisa
1.
Synthesis and anticancer activity of novel 9,13-disubstituted berberine derivatives.
Bioorg Med Chem Lett
; 30(2): 126821, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31812467
2.
Regression of castration-resistant prostate cancer by a novel compound QW07 targeting androgen receptor N-terminal domain.
Cell Biol Toxicol
; 36(5): 399-416, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32002708
3.
Determining the Drug-Like Properties of Ailanthone, a Novel Chinese Medicine Monomer with Anti-CRPC Activity.
Planta Med
; 86(7): 482-488, 2020 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-32168548
4.
Diastereoselective synthesis of 3,3-disubstituted 3-nitro-4-chromanone derivatives as potential antitumor agents.
Org Biomol Chem
; 17(5): 1062-1066, 2019 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30638240
5.
PubAngioGen: a database and knowledge for angiogenesis and related diseases.
Nucleic Acids Res
; 43(Database issue): D963-7, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25392416
6.
A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.
Org Biomol Chem
; 14(5): 1727-35, 2016 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26732459
7.
A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway.
J Cell Mol Med
; 19(2): 383-95, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25351103
8.
LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity.
J Pharmacol Exp Ther
; 355(3): 473-83, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26377911
9.
PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis.
J Mol Cell Cardiol
; 72: 28-38, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24560667
10.
WB518, a novel STAT3 inhibitor, effectively alleviates IMQ and TPA-induced animal psoriasis by inhibiting STAT3 phosphorylation and Keratin 17.
Int Immunopharmacol
; 127: 111344, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38086269
11.
Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer Treatment.
ACS Cent Sci
; 10(3): 579-594, 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38559310
12.
Remodeling the immune microenvironment for gastric cancer therapy through antagonism of prostaglandin E2 receptor 4.
Genes Dis
; 11(4): 101164, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38560505
13.
Selectively targeting BCL6 using a small molecule inhibitor is a potential therapeutic strategy for ovarian cancer.
Int J Biol Sci
; 20(2): 486-501, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38169532
14.
PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53-MDM2 loop.
Nucleic Acids Res
; 39(6): 2234-48, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21097889
15.
Combined treatment of disulfiram with PARP inhibitors suppresses ovarian cancer.
Front Oncol
; 13: 1154073, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37143950
16.
Selectively Targeting STAT3 Using a Small Molecule Inhibitor is a Potential Therapeutic Strategy for Pancreatic Cancer.
Clin Cancer Res
; 29(4): 815-830, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36374556
17.
Discovery of a Highly Potent and Selective MYOF Inhibitor with Improved Water Solubility for the Treatment of Gastric Cancer.
J Med Chem
; 66(24): 16917-16938, 2023 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38054798
18.
A small molecule BCL6 inhibitor as chemosensitizers in acute myeloid leukemia.
Biomed Pharmacother
; 166: 115358, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37634473
19.
Preclinical characterization of WB737, a potent and selective STAT3 inhibitor, in natural killer/T-cell lymphoma.
MedComm (2020)
; 4(4): e284, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37334274
20.
Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways.
Angiogenesis
; 15(3): 421-32, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22669534