RESUMO
Medications have been known to cause adverse drug reactions that affect various organs; these are mostly reversible reactions that improve with the cessation of the culprit medication. Losartan is an angiotensin-one receptor blocker which has been approved by the Food and Drug Administration (FDA) for the treatment of arterial hypertension. Fatigue, anemia, weakness, and cough are some of the common adverse effects of losartan. Acute hepatic injury has rarely been reported as an adverse effect of losartan. We report a case of a 61-year-old female with severe hepatic injury secondary to losartan use. None of the cases reported so far had such a high elevation of liver enzymes as seen in our patient.
RESUMO
Pulmonary artery (PA) catheterisation has been performed for over four decades. It is utilised in intensive care units and perioperatively to titrate fluid and pressor therapy. Major and minor complications have been reported. The catheter can infrequently loop and coil in the right atrium, right ventricle and superior vena cava .We report a case of coiling of the PA catheter in the main PA. A 33-year-old woman was admitted with multiorgan failure and shock. She required mechanical ventilation, was in severe pulmonary oedema and required vasopressors for shock. We placed a PA catheter to assist in the management of her haemodynamic collapse. The catheter coiled in the main pulmonary trunk, which is extremely rare. The catheter was removed without any complications.