Detalhe da pesquisa
1.
Genomic destabilization and its associated mutagenesis increase with senescence-associated phenotype expression.
Cancer Sci
; 112(2): 515-522, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33222327
2.
Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair.
Int J Mol Sci
; 22(22)2021 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830134
3.
Aberrations in DNA repair pathways in cancer and therapeutic significances.
Semin Cancer Biol
; 58: 29-46, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30922960
4.
Gamma-irradiated quiescent cells repair directly induced double-strand breaks but accumulate persistent double-strand breaks during subsequent DNA replication.
Genes Cells
; 21(7): 789-97, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27251002
5.
The Arf/p53 protein module, which induces apoptosis, down-regulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs.
J Biol Chem
; 288(19): 13269-77, 2013 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23536184
6.
Single base substitution signatures 17a, 17b, and 40 are induced by γ-ray irradiation in association with increased reactive oxidative species.
Heliyon
; 10(6): e28044, 2024 Mar 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38545229
7.
A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency.
NPJ Precis Oncol
; 8(1): 117, 2024 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38789724
8.
Induction of cancerous stem cells during embryonic stem cell differentiation.
J Biol Chem
; 287(44): 36777-91, 2012 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22961983
9.
Arf and p53 act as guardians of a quiescent cellular state by protecting against immortalization of cells with stable genomes.
Biochem Biophys Res Commun
; 432(1): 34-9, 2013 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23376716
10.
Genome destabilization-associated phenotypes arising as a consequence of therapeutic treatment are suppressed by Olaparib.
PLoS One
; 18(1): e0281168, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706121
11.
The quiescent cellular state is Arf/p53-dependent and associated with H2AX downregulation and genome stability.
Int J Mol Sci
; 13(5): 6492-6506, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22754379
12.
Echoed induction of nucleotide variants and chromosomal structural variants in cancer cells.
Sci Rep
; 12(1): 20964, 2022 12 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36470958
13.
Replication-stress-associated DSBs induced by ionizing radiation risk genomic destabilization and associated clonal evolution.
iScience
; 24(4): 102313, 2021 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33870130
14.
Resveratrol and its Related Polyphenols Contribute to the Maintenance of Genome Stability.
Sci Rep
; 10(1): 5388, 2020 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32214146
15.
Genomic-Destabilization-Associated Mutagenesis and Clonal Evolution of Cells with Mutations in Tumor-Suppressor Genes.
Cancers (Basel)
; 11(11)2019 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31653100
16.
Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro.
Nat Commun
; 10(1): 3925, 2019 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31477700
17.
Mismatch repair dependence of replication stress-associated DSB recognition and repair.
Heliyon
; 5(12): e03057, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32083205
18.
The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.
J Cell Biochem
; 105(1): 245-54, 2008 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18543256
19.
Sensitization of Cancer Cells to Radiation and Topoisomerase I Inhibitor Camptothecin Using Inhibitors of PARP and Other Signaling Molecules.
Cancers (Basel)
; 10(10)2018 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30274183
20.
Onset of deaminase APOBEC3B induction in response to DNA double-strand breaks.
Biochem Biophys Rep
; 16: 115-121, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30417129