Detalhe da pesquisa
1.
CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition.
Nature
; 604(7907): 749-756, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35444283
2.
Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease.
Mol Cell
; 78(6): 1152-1165.e8, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32516598
3.
HELB Is a Feedback Inhibitor of DNA End Resection.
Mol Cell
; 61(3): 405-418, 2016 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26774285
4.
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Mol Cell
; 49(5): 872-83, 2013 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23333306
5.
The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination.
Mol Cell
; 40(4): 619-31, 2010 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21055983
6.
A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.
Mol Syst Biol
; 9: 696, 2013 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24104479
7.
LSD1 is required for euchromatic origin firing and replication timing.
Signal Transduct Target Ther
; 7(1): 102, 2022 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35414135
8.
Guiding ATR and PARP inhibitor combinationswith chemogenomic screens.
Cell Rep
; 40(2): 111081, 2022 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35830811
9.
RP-3500: A Novel, Potent, and Selective ATR Inhibitor that is Effective in Preclinical Models as a Monotherapy and in Combination with PARP Inhibitors.
Mol Cancer Ther
; 21(2): 245-256, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34911817
10.
The CIP2A-TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer.
Nat Cancer
; 2(12): 1357-1371, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35121901
11.
Simultaneous exposure of Xenopus A6 kidney epithelial cells to concurrent mild sodium arsenite and heat stress results in enhanced hsp30 and hsp70 gene expression and the acquisition of thermotolerance.
Comp Biochem Physiol A Mol Integr Physiol
; 153(4): 417-24, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19358893
12.
Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cells.
Cell Stress Chaperones
; 15(3): 323-34, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19838833