Pesquisa | Portal de Pesquisa da BVS

1.

Autistic-like behaviour in Scn1a+/- mice and rescue by enhanced GABA-mediated neurotransmission.

Han, Sung; Tai, Chao; Westenbroek, Ruth E; Yu, Frank H; Cheah, Christine S; Potter, Gregory B; Rubenstein, John L; Scheuer, Todd; de la Iglesia, Horacio O; Catterall, William A.

Nature ; 489(7416): 385-90, 2012 Sep 20.

Artigo em Inglês | MEDLINE | ID: mdl-22914087

2.

Genetic background modulates impaired excitability of inhibitory neurons in a mouse model of Dravet syndrome.

Rubinstein, Moran; Westenbroek, Ruth E; Yu, Frank H; Jones, Christina J; Scheuer, Todd; Catterall, William A.

Neurobiol Dis ; 73: 106-17, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25281316

3.

Na(V)1.1 channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythms.

Han, Sung; Yu, Frank H; Schwartz, Michael D; Linton, Jonathan D; Bosma, Martha M; Hurley, James B; Catterall, William A; de la Iglesia, Horacio O.

Proc Natl Acad Sci U S A ; 109(6): E368-77, 2012 Feb 07.

Artigo em Inglês | MEDLINE | ID: mdl-22223655

4.

Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome.

Cheah, Christine S; Yu, Frank H; Westenbroek, Ruth E; Kalume, Franck K; Oakley, John C; Potter, Gregory B; Rubenstein, John L; Catterall, William A.

Proc Natl Acad Sci U S A ; 109(36): 14646-51, 2012 Sep 04.

Artigo em Inglês | MEDLINE | ID: mdl-22908258

5.

Protein kinase Cα/ß inhibitor Gö6976 promotes PC12 cell adhesion and spreading through membrane recruitment and activation of protein kinase CÎ´.

Jung, Sung Youn; Kim, O Bok; Kang, Hyun Ki; Jang, Da Hyun; Min, Byung-Moo; Yu, Frank H.

Exp Cell Res ; 319(3): 153-60, 2013 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-23063429

6.

Functional roles of a C-terminal signaling complex of CaV1 channels and A-kinase anchoring protein 15 in brain neurons.

Marshall, Misty R; Clark, John Patrick; Westenbroek, Ruth; Yu, Frank H; Scheuer, Todd; Catterall, William A.

J Biol Chem ; 286(14): 12627-39, 2011 Apr 08.

Artigo em Inglês | MEDLINE | ID: mdl-21224388

7.

Deletion of the distal C terminus of CaV1.2 channels leads to loss of beta-adrenergic regulation and heart failure in vivo.

Fu, Ying; Westenbroek, Ruth E; Yu, Frank H; Clark, John P; Marshall, Misty R; Scheuer, Todd; Catterall, William A.

J Biol Chem ; 286(14): 12617-26, 2011 Apr 08.

Artigo em Inglês | MEDLINE | ID: mdl-21216955

8.

Too many roads not taken.

Edwards, Aled M; Isserlin, Ruth; Bader, Gary D; Frye, Stephen V; Willson, Timothy M; Yu, Frank H.

Nature ; 470(7333): 163-5, 2011 Feb 10.

Artigo em Inglês | MEDLINE | ID: mdl-21307913

9.

Temperature- and age-dependent seizures in a mouse model of severe myoclonic epilepsy in infancy.

Oakley, John C; Kalume, Franck; Yu, Frank H; Scheuer, Todd; Catterall, William A.

Proc Natl Acad Sci U S A ; 106(10): 3994-9, 2009 Mar 10.

Artigo em Inglês | MEDLINE | ID: mdl-19234123

10.

Painful channels.

Catterall, William A; Yu, Frank H.

Neuron ; 52(5): 743-4, 2006 Dec 07.

Artigo em Inglês | MEDLINE | ID: mdl-17145494

11.

Neuromodulation of Na+ channel slow inactivation via cAMP-dependent protein kinase and protein kinase C.

Chen, Yuan; Yu, Frank H; Surmeier, D James; Scheuer, Todd; Catterall, William A.

Neuron ; 49(3): 409-20, 2006 Feb 02.

Artigo em Inglês | MEDLINE | ID: mdl-16446144

12.

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy.

Yu, Frank H; Mantegazza, Massimo; Westenbroek, Ruth E; Robbins, Carol A; Kalume, Franck; Burton, Kimberly A; Spain, William J; McKnight, G Stanley; Scheuer, Todd; Catterall, William A.

Nat Neurosci ; 9(9): 1142-9, 2006 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-16921370

13.

A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation.

Tang, Bin; Dutt, Karoni; Papale, Ligia; Rusconi, Raffaella; Shankar, Anupama; Hunter, Jessica; Tufik, Sergio; Yu, Frank H; Catterall, William A; Mantegazza, Massimo; Goldin, Alan L; Escayg, Andrew.

Neurobiol Dis ; 35(1): 91-102, 2009 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-19409490

14.

Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats.

Vo, Thuy T B; Jung, Eui-Man; Dang, Vu Hoang; Yoo, Yeong-Min; Choi, Kyung-Chul; Yu, Frank H; Jeung, Eui-Bae.

Reprod Biol Endocrinol ; 7: 104, 2009 Sep 26.

Artigo em Inglês | MEDLINE | ID: mdl-19781091

15.

Functional properties and differential neuromodulation of Na(v)1.6 channels.

Chen, Yuan; Yu, Frank H; Sharp, Elizabeth M; Beacham, Daniel; Scheuer, Todd; Catterall, William A.

Mol Cell Neurosci ; 38(4): 607-15, 2008 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-18599309

16.

NaV1.6 and NaV1.7 channels are major endogenous voltage-gated sodium channels in ND7/23 cells.

Lee, Jisoo; Kim, Shinae; Kim, Hye-Mi; Kim, Hyun Jeong; Yu, Frank H.

PLoS One ; 14(8): e0221156, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31419255

17.

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

Kalume, Franck; Yu, Frank H; Westenbroek, Ruth E; Scheuer, Todd; Catterall, William A.

J Neurosci ; 27(41): 11065-74, 2007 Oct 10.

Artigo em Inglês | MEDLINE | ID: mdl-17928448

18.

Voltage-gated ion channels and gating modifier toxins.

Catterall, William A; Cestèle, Sandrine; Yarov-Yarovoy, Vladimir; Yu, Frank H; Konoki, Keiichi; Scheuer, Todd.

Toxicon ; 49(2): 124-41, 2007 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-17239913

19.

Effects of the incorporation of Îµ-aminocaproic acid/chitosan particles to fibrin on cementoblast differentiation and cementum regeneration.

Park, Chan Ho; Oh, Joung-Hwan; Jung, Hong-Moon; Choi, Yoonnyoung; Rahman, Saeed Ur; Kim, Sungtae; Kim, Tae-Il; Shin, Hong-In; Lee, Yun-Sil; Yu, Frank H; Baek, Jeong-Hwa; Ryoo, Hyun-Mo; Woo, Kyung Mi.

Acta Biomater ; 61: 134-143, 2017 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-28764948

20.

Molecular determinants for modulation of persistent sodium current by G-protein betagamma subunits.

Mantegazza, Massimo; Yu, Frank H; Powell, Andrew J; Clare, Jeffrey J; Catterall, William A; Scheuer, Todd.

J Neurosci ; 25(13): 3341-9, 2005 Mar 30.

Artigo em Inglês | MEDLINE | ID: mdl-15800189

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