Detalhe da pesquisa
1.
NOTCH2 promotes osteoclast maturation and metabolism and modulates the transcriptome profile during osteoclastogenesis.
J Biol Chem
; 300(2): 105613, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38159855
2.
NOTCH2 sensitizes the chondrocyte to the inflammatory response of tumor necrosis factor α.
J Biol Chem
; 299(12): 105372, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37865314
3.
Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function.
J Biol Chem
; 297(6): 101376, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34742737
4.
Activation of Notch3 in osteoblasts/osteocytes causes compartment-specific changes in bone remodeling.
J Biol Chem
; 296: 100583, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33774049
5.
TDAG51 is a crucial regulator of maternal care and depressive-like behavior after parturition.
PLoS Genet
; 15(6): e1008214, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31251738
6.
Antisense oligonucleotides targeting Notch2 ameliorate the osteopenic phenotype in a mouse model of Hajdu-Cheney syndrome.
J Biol Chem
; 295(12): 3952-3964, 2020 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31992595
7.
The Hajdu Cheney mutation sensitizes mice to the osteolytic actions of tumor necrosis factor α.
J Biol Chem
; 294(39): 14203-14214, 2019 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371452
8.
Nuclear factor of activated T cells 1 and 2 are required for vertebral homeostasis.
J Cell Physiol
; 235(11): 8520-8532, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32329053
9.
An antibody to Notch3 reverses the skeletal phenotype of lateral meningocele syndrome in male mice.
J Cell Physiol
; 235(1): 210-220, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31188489
10.
The lateral meningocele syndrome mutation causes marked osteopenia in mice.
J Biol Chem
; 293(36): 14165-14177, 2018 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30042232
11.
The Hajdu Cheney Mutation Is a Determinant of B-Cell Allocation of the Splenic Marginal Zone.
Am J Pathol
; 188(1): 149-159, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29037852
12.
Induction of the Hajdu-Cheney Syndrome Mutation in CD19 B Cells in Mice Alters B-Cell Allocation but Not Skeletal Homeostasis.
Am J Pathol
; 188(6): 1430-1446, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29545197
13.
Sustained Notch2 signaling in osteoblasts, but not in osteoclasts, is linked to osteopenia in a mouse model of Hajdu-Cheney syndrome.
J Biol Chem
; 292(29): 12232-12244, 2017 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28592489
14.
Nuclear factor of activated T cells 2 is required for osteoclast differentiation and function in vitro but not in vivo.
J Cell Biochem
; 119(11): 9334-9345, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30010214
15.
Glucocorticoids inhibit notch target gene expression in osteoblasts.
J Cell Biochem
; 119(7): 6016-6023, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29575203
16.
Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis.
J Biol Chem
; 291(39): 20643-60, 2016 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27507811
17.
Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction.
J Biol Chem
; 290(15): 9660-73, 2015 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25716317
18.
Secretion of a truncated osteopetrosis-associated transmembrane protein 1 (OSTM1) mutant inhibits osteoclastogenesis through down-regulation of the B lymphocyte-induced maturation protein 1 (BLIMP1)-nuclear factor of activated T cells c1 (NFATc1) axis.
J Biol Chem
; 289(52): 35868-81, 2014 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25359771
19.
D-chiro-inositol negatively regulates the formation of multinucleated osteoclasts by down-regulating NFATc1.
J Clin Immunol
; 32(6): 1360-71, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22711011
20.
Use of antisense oligonucleotides to target Notch3 in skeletal cells.
PLoS One
; 17(5): e0268225, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35536858