Pesquisa | Portal de Pesquisa da BVS

1.

Structural basis for human Ca_v1.2 inhibition by multiple drugs and the neurotoxin calciseptine.

Gao, Shuai; Yao, Xia; Chen, Jiaofeng; Huang, Gaoxingyu; Fan, Xiao; Xue, Lingfeng; Li, Zhangqiang; Wu, Tong; Zheng, Yupeng; Huang, Jian; Jin, Xueqin; Wang, Yan; Wang, Zhifei; Yu, Yong; Liu, Lei; Pan, Xiaojing; Song, Chen; Yan, Nieng.

Cell ; 186(24): 5363-5374.e16, 2023 11 22.

Artigo em Inglês | MEDLINE | ID: mdl-37972591

2.

Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Ca_v channels.

Yao, Xia; Gao, Shuai; Wang, Jixin; Li, Zhangqiang; Huang, Jian; Wang, Yan; Wang, Zhifei; Chen, Jiaofeng; Fan, Xiao; Wang, Weipeng; Jin, Xueqin; Pan, Xiaojing; Yu, Yong; Lagrutta, Armando; Yan, Nieng.

Cell ; 185(25): 4801-4810.e13, 2022 Dec 08.

Artigo em Inglês | MEDLINE | ID: mdl-36417914

3.

Low-dose metformin targets the lysosomal AMPK pathway through PEN2.

Ma, Teng; Tian, Xiao; Zhang, Baoding; Li, Mengqi; Wang, Yu; Yang, Chunyan; Wu, Jianfeng; Wei, Xiaoyan; Qu, Qi; Yu, Yaxin; Long, Shating; Feng, Jin-Wei; Li, Chun; Zhang, Cixiong; Xie, Changchuan; Wu, Yaying; Xu, Zheni; Chen, Junjie; Yu, Yong; Huang, Xi; He, Ying; Yao, Luming; Zhang, Lei; Zhu, Mingxia; Wang, Wen; Wang, Zhi-Chao; Zhang, Mingliang; Bao, Yuqian; Jia, Weiping; Lin, Shu-Yong; Ye, Zhiyun; Piao, Hai-Long; Deng, Xianming; Zhang, Chen-Song; Lin, Sheng-Cai.

Nature ; 603(7899): 159-165, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35197629

4.

Virus-induced senescence is a driver and therapeutic target in COVID-19.

Lee, Soyoung; Yu, Yong; Trimpert, Jakob; Benthani, Fahad; Mairhofer, Mario; Richter-Pechanska, Paulina; Wyler, Emanuel; Belenki, Dimitri; Kaltenbrunner, Sabine; Pammer, Maria; Kausche, Lea; Firsching, Theresa C; Dietert, Kristina; Schotsaert, Michael; Martínez-Romero, Carles; Singh, Gagandeep; Kunz, Séverine; Niemeyer, Daniela; Ghanem, Riad; Salzer, Helmut J F; Paar, Christian; Mülleder, Michael; Uccellini, Melissa; Michaelis, Edward G; Khan, Amjad; Lau, Andrea; Schönlein, Martin; Habringer, Anna; Tomasits, Josef; Adler, Julia M; Kimeswenger, Susanne; Gruber, Achim D; Hoetzenecker, Wolfram; Steinkellner, Herta; Purfürst, Bettina; Motz, Reinhard; Di Pierro, Francesco; Lamprecht, Bernd; Osterrieder, Nikolaus; Landthaler, Markus; Drosten, Christian; García-Sastre, Adolfo; Langer, Rupert; Ralser, Markus; Eils, Roland; Reimann, Maurice; Fan, Dorothy N Y; Schmitt, Clemens A.

Nature ; 599(7884): 283-289, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34517409

5.

Molecular and structural basis of the dual regulation of the polycystin-2 ion channel by small-molecule ligands.

Wang, Zhifei; Chen, Mengying; Su, Qiang; Morais, Tiago D C; Wang, Yan; Nazginov, Elianna; Pillai, Akhilraj R; Qian, Feng; Shi, Yigong; Yu, Yong.

Proc Natl Acad Sci U S A ; 121(12): e2316230121, 2024 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-38483987

6.

Type II and IV toxin-antitoxin systems coordinately stabilize the integrative and conjugative element of the ICESa2603 family conferring multiple drug resistance in Streptococcus suis.

Gu, Qibing; Zhu, Xiayu; Yu, Yong; Jiang, Tao; Pan, Zihao; Ma, Jiale; Yao, Huochun.

PLoS Pathog ; 20(4): e1012169, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38640137

7.

Entanglement of two quantum memories via fibres over dozens of kilometres.

Yu, Yong; Ma, Fei; Luo, Xi-Yu; Jing, Bo; Sun, Peng-Fei; Fang, Ren-Zhou; Yang, Chao-Wei; Liu, Hui; Zheng, Ming-Yang; Xie, Xiu-Ping; Zhang, Wei-Jun; You, Li-Xing; Wang, Zhen; Chen, Teng-Yun; Zhang, Qiang; Bao, Xiao-Hui; Pan, Jian-Wei.

Nature ; 578(7794): 240-245, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-32051600

8.

Comprehensive single-cell analysis deciphered microenvironmental dynamics and immune regulator olfactomedin 4 in pathogenesis of gallbladder cancer.

He, Huisi; Chen, Shuzhen; Yu, Yong; Fan, Zhecai; Qian, Youwen; Dong, Yaping; Song, Yuting; Zhong, Caiming; Sun, Xiaojuan; Cao, Qiqi; Li, Shiyao; Huang, Weihan; Li, Wenxin; Zhuang, Mingzhu; Yang, Jinxian; Wang, Xianming; Wang, Jiaqian; Wu, Dongfang; Wang, Hongyang; Wen, Wen.

Gut ; 2024 May 06.

Artigo em Inglês | MEDLINE | ID: mdl-38719336

9.

The diverse effects of pathogenic point mutations on ion channel activity of a gain-of-function polycystin-2.

Wang, Yan; Wang, Zhifei; Pavel, Mahmud Arif; Ng, Courtney; Kashyap, Parul; Li, Bin; Morais, Tiago D C; Ulloa, Gabriella A; Yu, Yong.

J Biol Chem ; 299(5): 104674, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37028763

10.

Dynamic Stomach Model-Capillary Electrophoresis-ICPMS for Evaluation of Release and Transformation Behaviors of Arsenic Species from Microplastics during Digestion.

Zhang, Xiao; Jiang, Xin-Yi; Cai, Ji-Ying; Chen, Shuai; Yu, Yong-Liang; Wang, Jian-Hua.

Anal Chem ; 96(18): 7155-7162, 2024 May 07.

Artigo em Inglês | MEDLINE | ID: mdl-38652710

11.

A Portable Microplasma Optical Emission Spectrometric Device with Online Digestion Function for Field and Sensitive Determination of Lead in Biological Samples.

Cai, Ji-Ying; Zhang, Xiao; Wei, Yu-Jia; Chen, Shuai; Yu, Yong-Liang; Wang, Jian-Hua.

Anal Chem ; 96(9): 3733-3738, 2024 Mar 05.

Artigo em Inglês | MEDLINE | ID: mdl-38373274

12.

Urine Self-Sampling Kit Combined with an Automated Preparation-Sampler Device for Convenient and Reliable Analysis of Arsenic Metabolites by HPLC-ICPMS.

Zhang, Xiao; Jiang, Xin-Yi; Zhao, Lin; Chen, Shuai; Yu, Yong-Liang; Wang, Jian-Hua.

Anal Chem ; 96(4): 1742-1749, 2024 01 30.

Artigo em Inglês | MEDLINE | ID: mdl-38221770

13.

Transcriptomics confirms IRF1 as a key regulator of pyroptosis in diabetic retinopathy.

Xian, Yang; Wang, Xingli; Yu, Yong; Chen, XiaoLong.

Biochem Biophys Res Commun ; 709: 149760, 2024 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-38554602

14.

Th2-skewed peripheral T helper cells drives B cells in allergic bronchopulmonary aspergillosis.

Luo, Rong-Guang; Wu, Yi-Fan; Lu, Hai-Wen; Weng, Dong; Xu, Jia-Yan; Wang, Le-Le; Zhang, Li-Sha; Zhao, Cai-Qi; Li, Jian-Xiong; Yu, Yong; Jia, Xin-Ming; Xu, Jin-Fu.

Eur Respir J ; 2024 Mar 21.

Artigo em Inglês | MEDLINE | ID: mdl-38514095

15.

SssP1, a Fimbria-like component of Streptococcus suis, binds to the vimentin of host cells and contributes to bacterial meningitis.

Pan, Zihao; He, Peijuan; Zhang, Yue; Gu, Qibing; Chen, Shengsheng; Yu, Yong; Shao, Jing; Wang, Kaicheng; Wu, Zongfu; Yao, Huochun; Ma, Jiale.

PLoS Pathog ; 18(7): e1010710, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35853077

16.

Î´13C of bulk organic matter and cellulose reveal post-photosynthetic fractionation during ontogeny in C4 grass leaves.

Yu, Yong Zhi; Liu, Hai Tao; Yang, Fang; Li, Lei; Schäufele, Rudi; Tcherkez, Guillaume; Schnyder, Hans; Gong, Xiao Ying.

J Exp Bot ; 75(5): 1451-1464, 2024 Feb 28.

Artigo em Inglês | MEDLINE | ID: mdl-37943576

17.

Conserved Role of mTORC1 Signaling in B Cell Immunity in Teleost Fish.

Cao, Jia-Feng; Ding, Li-Guo; Wang, Qing-Chao; Han, Guang-Kun; Qin, Da-Cheng; Cheng, Gao-Feng; Dong, Zhao-Ran; Mu, Qing-Jiang; Kong, Wei-Guang; Liu, Xia; Yu, Yong-Yao; Xu, Zhen.

J Immunol ; 209(6): 1095-1107, 2022 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-35985789

18.

Development and validation of a prognostic model for 90-day survival in patients with alcohol-associated cirrhosis and acute decompensation.

Quan, Hui; Yu, Hao; Liu, Xiao-Li; Xiong, Fei-Xiang; Hou, Yi-Xin; Wang, Xian-Bo; Yang, Zhi-Yun; Jiang, Yu-Yong.

Hepatol Res ; 2024 Jan 19.

Artigo em Inglês | MEDLINE | ID: mdl-38241146

19.

Senescence-associated reprogramming promotes cancer stemness.

Milanovic, Maja; Fan, Dorothy N Y; Belenki, Dimitri; Däbritz, J Henry M; Zhao, Zhen; Yu, Yong; Dörr, Jan R; Dimitrova, Lora; Lenze, Dido; Monteiro Barbosa, Ines A; Mendoza-Parra, Marco A; Kanashova, Tamara; Metzner, Marlen; Pardon, Katharina; Reimann, Maurice; Trumpp, Andreas; Dörken, Bernd; Zuber, Johannes; Gronemeyer, Hinrich; Hummel, Michael; Dittmar, Gunnar; Lee, Soyoung; Schmitt, Clemens A.

Nature ; 553(7686): 96-100, 2018 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-29258294

20.

Sncg, Mybpc1, and Parm1 Classify subpopulations of VIP-expressing interneurons in layers 2/3 of the somatosensory cortex.

Jiang, Shao-Na; Cao, Jun-Wei; Liu, Lin-Yun; Zhou, Ying; Shan, Guang-Yao; Fu, Ying-Hui; Shao, Yun-Chao; Yu, Yong-Chun.

Cereb Cortex ; 33(8): 4293-4304, 2023 04 04.

Artigo em Inglês | MEDLINE | ID: mdl-36030380

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