Detalhe da pesquisa
1.
IpdE1-IpdE2 Is a Heterotetrameric Acyl Coenzyme A Dehydrogenase That Is Widely Distributed in Steroid-Degrading Bacteria.
Biochemistry
; 59(10): 1113-1123, 2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32101684
2.
Hit Generation in TB Drug Discovery: From Genome to Granuloma.
Chem Rev
; 118(4): 1887-1916, 2018 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29384369
3.
Mycobacterium tuberculosis Exploits a Heterohexameric Enoyl-CoA Hydratase Retro-Aldolase Complex for Cholesterol Catabolism.
Biochemistry
; 58(41): 4224-4235, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31568719
4.
Correction to Hit Generation in TB Drug Discovery: From Genome to Granuloma.
Chem Rev
; 119(12): 7718, 2019 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31058490
5.
A Chemoproteomic Approach to Elucidate the Mechanism of Action of 6-Azasteroids with Unique Activity in Mycobacteria.
ACS Infect Dis
; 9(10): 1993-2004, 2023 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37774412
6.
The pursuit of mechanism of action: uncovering drug complexity in TB drug discovery.
RSC Chem Biol
; 2(2): 423-440, 2021 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33928253
7.
Enzymatic ß-Oxidation of the Cholesterol Side Chain in Mycobacterium tuberculosis Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA.
ACS Infect Dis
; 7(6): 1739-1751, 2021 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33826843
8.
Corrigendum: Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis.
Front Cell Infect Microbiol
; 11: 765326, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34650934
9.
Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis.
Front Cell Infect Microbiol
; 11: 709972, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34395315
10.
Post-translational Succinylation of Mycobacterium tuberculosis Enoyl-CoA Hydratase EchA19 Slows Catalytic Hydration of Cholesterol Catabolite 3-Oxo-chol-4,22-diene-24-oyl-CoA.
ACS Infect Dis
; 6(8): 2214-2224, 2020 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32649175
11.
Mce3R Stress-Resistance Pathway Is Vulnerable to Small-Molecule Targeting That Improves Tuberculosis Drug Activities.
ACS Infect Dis
; 5(7): 1239-1251, 2019 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31012313