Detalhe da pesquisa
1.
Radiosynthesis of [thiocarbonyl-11C]disulfiram and its first PET study in mice.
Bioorg Med Chem Lett
; 30(6): 126998, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32014383
2.
Dynamic Changes in Striatal mGluR1 But Not mGluR5 during Pathological Progression of Parkinson's Disease in Human Alpha-Synuclein A53T Transgenic Rats: A Multi-PET Imaging Study.
J Neurosci
; 36(2): 375-84, 2016 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26758830
3.
[11C]BCTC: Radiosynthesis and in vivo binding to transient receptor potential vanilloid subfamily member 1 (TRPV1) receptor in the mouse trigeminal nerve.
Bioorg Med Chem Lett
; 27(19): 4521-4524, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28888821
4.
Synthesis and evaluation of 1-(cyclopropylmethyl)-4-(4-[11C]methoxyphenyl)-piperidin-1-yl-2-oxo-1,2-dihydropyridine-3-carbonitrile ([11C]CMDC) for PET imaging of metabotropic glutamate receptor 2 in the rat brain.
Bioorg Med Chem
; 25(3): 1014-1021, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049619
5.
Radiosynthesis and evaluation of 5-methyl-N-(4-[(11)C]methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine ([(11)C]ADX88178) as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 (mGluR4).
Bioorg Med Chem Lett
; 26(2): 370-374, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26707390
6.
N-(3,4-Dimethylisoxazol-5-yl)piperazine-4-[4-(2-fluoro-4-[(11)C]methylphenyl)thiazol-2-yl]-1-carboxamide: A promising positron emission tomography ligand for fatty acid amide hydrolase.
Bioorg Med Chem
; 24(4): 627-34, 2016 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26740152
7.
Radiosynthesis and preliminary PET evaluation of glycogen synthase kinase 3ß (GSK-3ß) inhibitors containing [(11)C]methylsulfanyl, [(11)C]methylsulfinyl or [(11)C]methylsulfonyl groups.
Bioorg Med Chem Lett
; 25(16): 3230-3, 2015 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26067173
8.
Development of the Fibronectin-Mimetic Peptide KSSPHSRN(SG)5RGDSP as a Novel Radioprobe for Molecular Imaging of the Cancer Biomarker α5ß1 Integrin.
Biol Pharm Bull
; 38(11): 1722-31, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26277991
9.
Characterization of a novel acetamidobenzoxazolone-based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain.
J Neurochem
; 129(4): 712-20, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24484439
10.
Molecular imaging of ectopic metabotropic glutamate 1 receptor in melanoma with a positron emission tomography radioprobe (18) F-FITM.
Int J Cancer
; 135(8): 1852-9, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24643962
11.
[(11)C-carbonyl]CEP-32496: radiosynthesis, biodistribution and PET study of brain uptake in P-gp/BCRP knockout mice.
Bioorg Med Chem Lett
; 24(15): 3574-7, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24930831
12.
Synthesis and evaluation of new (18)F-labelled acetamidobenzoxazolone-based radioligands for imaging of the translocator protein (18 kDa, TSPO) in the brain.
Org Biomol Chem
; 12(47): 9621-30, 2014 Dec 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25339090
13.
Monitoring neuroprotective effects using positron emission tomography with [11C]ITMM, a radiotracer for metabotropic glutamate 1 receptor.
Stroke
; 44(9): 2567-72, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23908068
14.
Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.
Bioorg Med Chem
; 21(17): 5316-22, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23830697
15.
Characterization of 1-(2-[18F] fluoro-3-pyridyl)-4-(2-isopropyl-1-oxo- isoindoline-5-yl)-5-methyl-1H-1,2,3-triazole, a PET ligand for imaging the metabotropic glutamate receptor type 1 in rat and monkey brains.
J Neurochem
; 121(1): 115-24, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21668889
16.
Translocator protein (18 kDa), a potential molecular imaging biomarker for non-invasively distinguishing non-alcoholic fatty liver disease.
J Hepatol
; 57(5): 1076-82, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22796156
17.
Imaging for metabotropic glutamate receptor subtype 1 in rat and monkey brains using PET with [18F]FITM.
Eur J Nucl Med Mol Imaging
; 39(4): 632-41, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22113620
18.
Utilization of [11C]phosgene for radiosynthesis of N-(2-{3-[3,5-bis(trifluoromethyl)]phenyl[11C]ureido}ethyl)glycyrrhetinamide, an inhibitory agent for proteasome and kinase in tumors.
Bioorg Med Chem Lett
; 22(11): 3594-7, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22546673
19.
Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C]DAC with ultra-high specific activity.
Neuroimage
; 54(1): 123-30, 2011 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20705143
20.
Radiosynthesis of three [11C]ureido-substituted benzenesulfonamides as PET probes for carbonic anhydrase IX in tumors.
Bioorg Med Chem Lett
; 21(23): 7017-20, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22014831