Detalhe da pesquisa
1.
Noncanonical mitochondrial unfolded protein response impairs placental oxidative phosphorylation in early-onset preeclampsia.
Proc Natl Acad Sci U S A
; 116(36): 18109-18118, 2019 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31439814
2.
Excessive endoplasmic reticulum stress drives aberrant mouse trophoblast differentiation and placental development leading to pregnancy loss.
J Physiol
; 599(17): 4153-4181, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34269420
3.
HYPOXIA AND REPRODUCTIVE HEALTH: Oxygen and development of the human placenta.
Reproduction
; 161(1): F53-F65, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32438347
4.
Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine-Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy.
Am J Pathol
; 189(2): 467-478, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30448406
5.
Placental Adaptation to Early-Onset Hypoxic Pregnancy and Mitochondria-Targeted Antioxidant Therapy in a Rodent Model.
Am J Pathol
; 188(12): 2704-2716, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30248337
6.
Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker.
Circulation
; 136(19): 1824-1839, 2017 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28904069
7.
Endothelin-1 down-regulates matrix metalloproteinase 14 and 15 expression in human first trimester trophoblasts via endothelin receptor type B.
Hum Reprod
; 32(1): 46-54, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864359
8.
Placental endoplasmic reticulum stress negatively regulates transcription of placental growth factor via ATF4 and ATF6ß: implications for the pathophysiology of human pregnancy complications.
J Pathol
; 238(4): 550-61, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26648175
9.
Placental endoplasmic reticulum stress in gestational diabetes: the potential for therapeutic intervention with chemical chaperones and antioxidants.
Diabetologia
; 59(10): 2240-50, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27406815
10.
Morphological and molecular changes in the murine placenta exposed to normobaric hypoxia throughout pregnancy.
J Physiol
; 594(5): 1371-88, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26278110
11.
Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early- and late-onset pre-eclampsia.
J Pathol
; 234(2): 262-76, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24931423
12.
Genomic Selection Signals in Andean Highlanders Reveal Adaptive Placental Metabolic Phenotypes That Are Disrupted in Preeclampsia.
Hypertension
; 81(2): 319-329, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38018457
13.
Endothelin-1 induces endoplasmic reticulum stress by activating the PLC-IP(3) pathway: implications for placental pathophysiology in preeclampsia.
Am J Pathol
; 180(6): 2309-20, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22503784
14.
Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude.
FASEB J
; 26(5): 1970-81, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22267338
15.
Endoplasmic reticulum stress disrupts placental morphogenesis: implications for human intrauterine growth restriction.
J Pathol
; 228(4): 554-64, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22733590
16.
Protocol for culturing the endocrine junctional zone of the mouse placenta in serum-free medium.
STAR Protoc
; 4(3): 102384, 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37384519
17.
Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism.
iScience
; 26(1): 105911, 2023 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36660474
18.
Elevated homocysteine activates unfolded protein responses and causes aberrant trophoblast differentiation and mouse blastocyst development.
Physiol Rep
; 10(18): e15467, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36117391
19.
Chronic Hypoxia in Ovine Pregnancy Recapitulates Physiological and Molecular Markers of Preeclampsia in the Mother, Placenta, and Offspring.
Hypertension
; 79(7): 1525-1535, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534925
20.
Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker.
Nat Commun
; 12(1): 3714, 2021 06 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140513