Detalhe da pesquisa
1.
2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1δ/ε.
Amino Acids
; 43(4): 1577-91, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22331384
2.
Casein Kinase 1D Encodes a Novel Drug Target in Hedgehog-GLI-Driven Cancers and Tumor-Initiating Cells Resistant to SMO Inhibition.
Cancers (Basel)
; 13(16)2021 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34439381
3.
Thienopyrimidines as ß3-adrenoceptor agonists: hit-to-lead optimization.
Bioorg Med Chem Lett
; 20(20): 6108-15, 2010 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20833036
4.
A new promising candidate to overcome drug resistant herpes simplex virus infections.
Antiviral Res
; 149: 202-210, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29155164
5.
Inhibitors of dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) exert a strong anti-herpesviral activity.
Antiviral Res
; 143: 113-121, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28400201
6.
DYRK1B as therapeutic target in Hedgehog/GLI-dependent cancer cells with Smoothened inhibitor resistance.
Oncotarget
; 7(6): 7134-48, 2016 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26784250
7.
Difluoro-dioxolo-benzoimidazol-benzamides as potent inhibitors of CK1δ and ε with nanomolar inhibitory activity on cancer cell proliferation.
J Med Chem
; 57(19): 7933-46, 2014 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25191940
8.
Design and synthesis of a novel series of bicyclic heterocycles as potent γ-secretase modulators.
J Med Chem
; 55(21): 9089-106, 2012 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22650177
9.
Analogues of morphanthridine and the tear gas dibenz[b,f][1,4]oxazepine (CR) as extremely potent activators of the human transient receptor potential ankyrin 1 (TRPA1) channel.
J Med Chem
; 53(19): 7011-20, 2010 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20806939