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1.
PLoS One ; 16(1): e0246052, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33497403

RESUMO

In this study transcriptome was analyzed on two fibrous varieties of flax: the susceptible Regina and the resistant Nike. The experiment was carried out on 2-week-old seedlings, because in this phase of development flax is the most susceptible to infection. We analyzed the whole seedlings, which allowed us to recognize the systemic response of the plants to the infection. We decided to analyze two time points: 24h and 48h, because our goal was to learn the mechanisms activated in the initial stages of infection, these points were selected based on the previous analysis of chitinase gene expression, whose increase in time of Fusarium oxysporum lini infection has been repeatedly confirmed both in the case of flax and other plant species. The results show that although qualitatively the responses of the two varieties are similar, it is the degree of the response that plays the role in the differences of their resistance to F. oxysporum.


Assuntos
Linho/genética , Fusarium/isolamento & purificação , Regulação da Expressão Gênica de Plantas , Micoses/genética , Doenças das Plantas/microbiologia , Plântula/genética , Transcriptoma , Resistência à Doença/genética , Linho/microbiologia , Perfilação da Expressão Gênica , Micoses/metabolismo , Doenças das Plantas/genética , Plântula/metabolismo , Plântula/microbiologia
2.
Curr Pharm Des ; 25(20): 2241-2263, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31333096

RESUMO

The incidence of inflammatory skin diseases is increasing, so the search for relevant therapeutics is of major concern. Plants are rich in phytochemicals which can alleviate many symptoms. In this review, we concentrate on compounds found in the seeds of widely cultivated plants, regularly used for oil production. The oils from these plants are often used to alleviate the symptoms of inflammatory diseases through synergetic action of unsaturated fatty acids and other phytochemicals most commonly derived from the terpenoid pathway. The knowledge of the chemical composition of oil seeds and the understanding of the mechanisms of action of single components should allow for a more tailored approach for the treatment for many diseases. In many cases, these seeds could serve as an efficient material for the isolation of pure phytochemicals. Here we present the content of phytochemicals, assumed to be responsible for healing properties of plant oils in a widely cultivated oil seed plants and review the proposed mechanism of action for fatty acids, selected mono-, sesqui-, di- and triterpenes, carotenoids, tocopherol and polyphenols.


Assuntos
Inflamação/tratamento farmacológico , Fitoterapia , Óleos de Plantas/uso terapêutico , Dermatopatias/tratamento farmacológico , Humanos , Compostos Fitoquímicos/uso terapêutico , Sementes/química
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