Detalhe da pesquisa
1.
Stapled peptides as scaffolds for developing radiotracers for intracellular targets: Preliminary evaluation of a radioiodinated MDM2-binding stapled peptide in the SJSA-1 osteosarcoma model.
Bioorg Med Chem Lett
; 66: 128725, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35436588
2.
Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation.
Mol Pharm
; 18(10): 3871-3881, 2021 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34523337
3.
Labeling a TCO-functionalized single domain antibody fragment with 18F via inverse electron demand Diels Alder cycloaddition using a fluoronicotinyl moiety-bearing tetrazine derivative.
Bioorg Med Chem
; 28(17): 115634, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32773089
4.
Labeling Single Domain Antibody Fragments with Fluorine-18 Using 2,3,5,6-Tetrafluorophenyl 6-[18F]Fluoronicotinate Resulting in High Tumor-to-Kidney Ratios.
Mol Pharm
; 16(1): 214-226, 2019 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30427188
5.
Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe.
Nanotechnology
; 30(27): 275101, 2019 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30856613
6.
Observations on the Effects of Residualization and Dehalogenation on the Utility of N-Succinimidyl Ester Acylation Agents for Radioiodination of the Internalizing Antibody Trastuzumab.
Molecules
; 24(21)2019 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31671554
7.
An Efficient Method for Labeling Single Domain Antibody Fragments with 18F Using Tetrazine- Trans-Cyclooctene Ligation and a Renal Brush Border Enzyme-Cleavable Linker.
Bioconjug Chem
; 29(12): 4090-4103, 2018 12 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30384599
8.
Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors.
Bioorg Med Chem Lett
; 28(4): 694-699, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29366652
9.
Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: Chemistry and preliminary evaluation.
Bioorg Med Chem
; 26(8): 1939-1949, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29534937
10.
d-Amino Acid Peptide Residualizing Agents for Protein Radioiodination: Effect of Aspartate for Glutamate Substitution.
Molecules
; 23(5)2018 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29783774
11.
Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats.
Invest New Drugs
; 34(2): 149-58, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26728879
12.
N-Succinimidyl 3-((4-(4-[(18)F]fluorobutyl)-1H-1,2,3-triazol-1-yl)methyl)-5-(guanidinomethyl)benzoate ([(18)F]SFBTMGMB): a residualizing label for (18)F-labeling of internalizing biomolecules.
Org Biomol Chem
; 14(4): 1261-71, 2016 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26645790
13.
PSMA-reactive NB7 single domain antibody fragment: A potential scaffold for developing prostate cancer theranostics.
Nucl Med Biol
; 134-135: 108913, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38703588
14.
A third generation PSMA-targeted agent [211At]YF2: Synthesis and in vivo evaluation.
Nucl Med Biol
; 134-135: 108916, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38703587
15.
In situ growth of a PEG-like polymer from the C terminus of an intein fusion protein improves pharmacokinetics and tumor accumulation.
Proc Natl Acad Sci U S A
; 107(38): 16432-7, 2010 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-20810920
16.
DNA Repair Inhibitors: Potential Targets and Partners for Targeted Radionuclide Therapy.
Pharmaceutics
; 15(7)2023 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37514113
17.
Effective Treatment of Human Breast Carcinoma Xenografts with Single-Dose 211At-Labeled Anti-HER2 Single-Domain Antibody Fragment.
J Nucl Med
; 64(1): 124-130, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618478
18.
In situ growth of a stoichiometric PEG-like conjugate at a protein's N-terminus with significantly improved pharmacokinetics.
Proc Natl Acad Sci U S A
; 106(36): 15231-6, 2009 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19706892
19.
Site-Specific Radiohalogenation of a HER2-Targeted Single-Domain Antibody Fragment Using a Novel Residualizing Prosthetic Agent.
J Med Chem
; 65(22): 15358-15373, 2022 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36368007
20.
Evaluation of an 131I-labeled HER2-specific single domain antibody fragment for the radiopharmaceutical therapy of HER2-expressing cancers.
Sci Rep
; 12(1): 3020, 2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35194100