Detalhe da pesquisa
1.
Tralesinidase Alfa Enzyme Replacement Therapy Prevents Disease Manifestations in a Canine Model of Mucopolysaccharidosis Type IIIB.
J Pharmacol Exp Ther
; 382(3): 277-286, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35717448
2.
Longitudinal Natural History of Pediatric Subjects Affected with Mucopolysaccharidosis IIIB.
J Pediatr
; 249: 50-58.e2, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35709957
3.
A phase I/II study on intracerebroventricular tralesinidase alfa in patients with Sanfilippo syndrome type B.
J Clin Invest
; 133(2)2023 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36413418
4.
Safety, pharmacokinetics and CNS distribution of tralesinidase alfa administered via intracerebroventricular infusion to juvenile cynomolgus monkeys.
Toxicol Rep
; 10: 357-366, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923444
5.
Characterization of binding, functional activity, and contractile responses of the selective 5-HT1F receptor agonist lasmiditan.
Br J Pharmacol
; 176(24): 4681-4695, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31418454
6.
Macrophage-specific chemokines induced via innate immunity by amino acid copolymers and their role in EAE.
PLoS One
; 6(12): e26274, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22194778
7.
Safety, pharmacokinetic, and pharmacodynamic evaluations of PI-2301, a potent immunomodulator, in a first-in-human, single-ascending-dose study in healthy volunteers.
J Clin Pharmacol
; 51(5): 649-60, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20940336
8.
Targeting IL-15 receptor-bearing cells with an antagonist mutant IL-15/Fc protein prevents disease development and progression in murine collagen-induced arthritis.
J Immunol
; 173(9): 5818-26, 2004 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15494535
9.
CD25+ cell depletion hastens the onset of severe disease in collagen-induced arthritis.
Arthritis Rheum
; 48(5): 1452-60, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12746920
10.
Association between HLA class II genes and autoantibodies to cyclic citrullinated peptides (CCPs) influences the severity of rheumatoid arthritis.
Arthritis Rheum
; 50(7): 2113-21, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15248208