Detalhe da pesquisa
1.
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT6 receptor occupancy from non-human primates to humans.
Biopharm Drug Dispos
; 44(1): 48-59, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36825693
2.
Brain pharmacology of intrathecal antisense oligonucleotides revealed through multimodal imaging.
JCI Insight
; 4(20)2019 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31619586
3.
131I-tositumomab therapy as initial treatment for follicular lymphoma.
N Engl J Med
; 352(5): 441-9, 2005 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-15689582
4.
MicroPET detection of regional brain activation induced by colonic distention in a rat model of visceral hypersensitivity.
J Vet Med Sci
; 70(1): 43-9, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18250571
5.
The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging.
J Med Chem
; 60(20): 8538-8551, 2017 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28957634
6.
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman Primates.
J Med Chem
; 60(18): 7764-7780, 2017 09 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-28817277
7.
Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme.
J Nucl Med
; 57(9): 1448-53, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27199356
8.
Accurate dosimetry in 131I radionuclide therapy using patient-specific, 3-dimensional methods for SPECT reconstruction and absorbed dose calculation.
J Nucl Med
; 46(5): 840-9, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15872359
9.
The discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242).
J Med Chem
; 58(10): 4291-308, 2015 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25905800
10.
Update on hybrid conjugate-view SPECT tumor dosimetry and response in 131I-tositumomab therapy of previously untreated lymphoma patients.
J Nucl Med
; 44(3): 457-64, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12621015
11.
Comparison of attenuation-corrected and non-corrected FDG-PET images for axillary nodal staging in newly diagnosed breast cancer.
Mol Imaging Biol
; 4(2): 161-9, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14537139
12.
Reproducibility of common semi-quantitative parameters for evaluating lung cancer glucose metabolism with positron emission tomography using 2-deoxy-2-[18F]fluoro-D-glucose.
Mol Imaging Biol
; 4(2): 171-8, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14537140
13.
A positron-emitting internal marker for identification of normal tissue by positron emission tomography: phantom studies and validation in patients.
Mol Imaging Biol
; 5(2): 79-85, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-14499148
14.
Expression of hexokinase II and Glut-1 in untreated human breast cancer.
Nucl Med Biol
; 29(4): 443-53, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12031879
15.
Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator.
J Med Chem
; 57(3): 861-77, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24392688
16.
Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand.
J Med Chem
; 56(11): 4568-79, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23651455
17.
[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells.
Clin Cancer Res
; 18(5): 1303-12, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22170262
18.
The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH).
Nucl Med Biol
; 39(7): 1058-67, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22571907
19.
PF-03732010: a fully human monoclonal antibody against P-cadherin with antitumor and antimetastatic activity.
Clin Cancer Res
; 16(21): 5177-88, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20829331
20.
Bias reduction in correlation of radiation-absorbed dose with response.
J Nucl Med
; 45(7): 1271; author reply 1271-2, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15235076