Detalhe da pesquisa
1.
Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia.
Molecules
; 26(16)2021 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34443679
2.
Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis.
Am J Respir Cell Mol Biol
; 62(2): 178-190, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31419911
3.
Cannabidiol-Derived Cannabinoids: The Unregulated Designer Drug Market Following the 2018 Farm Bill.
Med Cannabis Cannabinoids
; 7(1): 10-18, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38352661
4.
Anandamide is an Early Blood Biomarker of Hermansky-Pudlak Syndrome Pulmonary Fibrosis.
medRxiv
; 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38798603
5.
In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosis.
Biomed Pharmacother
; 168: 115178, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37890204
6.
Chronic and Binge Alcohol Ingestion Increases Truncated Oxidized Phosphatidylcholines in Mice Lungs Due to Increased Oxidative Stress.
Front Physiol
; 13: 860449, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35685280
7.
Synthesis, Biological Evaluation, and Molecular Modeling Studies of 3,4-Diarylpyrazoline Series of Compounds as Potent, Nonbrain Penetrant Antagonists of Cannabinoid-1 (CB1R) Receptor with Reduced Lipophilicity.
J Med Chem
; 65(3): 2374-2387, 2022 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084860
8.
Peripheral Hybrid CB1R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis.
Front Endocrinol (Lausanne)
; 12: 744857, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34650521
9.
Functional Selectivity of a Biased Cannabinoid-1 Receptor (CB1R) Antagonist.
ACS Pharmacol Transl Sci
; 4(3): 1175-1187, 2021 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34151207
10.
CB1 R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky-Pudlak syndrome.
Clin Transl Med
; 11(7): e471, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34323400
11.
Synthetic cannabinoids induce acute lung inflammation via cannabinoid receptor 1 activation.
ERJ Open Res
; 6(3)2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-32832534