RESUMO
Sleep apnea hypopnea syndrome (SAHS) is an independent risk factor for various cardiovascular diseases. Electrocardiogram (ECG) features such as the RR, PR, QT, QTc, Tpe intervals and the Tpe/QT, Tpe/QTc ratios are used to predict and study cardiovascular diseases. It is not clear whether regular patterns of PR and Tpe-related features across sleep stages exist in SAHSs or healthy controls nor whether sleep stages affect the short- and long-range influences of respiratory events on ECG indices. We enrolled 36 healthy controls and 35 patients with SAHS in our study and analyzed the abovementioned ECG features. In the healthy controls, a significant regularity existed in these indices across sleep stages, which were weakened or disturbed in the patient group, especially the Tpe-related features. The differences between the patients and healthy controls were generally consistent across all sleep stages: patients had smaller RR, PR, QT and Tpe/QTc values, but larger QTc, Tpe and Tpe/QT values. After filtering the short-range influence of respiratory events, the differences in most features remained highly significant, except the QT interval. In the patient group, respiratory events decreased RR and PR intervals in most sleep stages and increased the Tpe-related features' values in deep sleep stages. These results may aid in the study of the relationships among SAHS, sleep disorders and cardiovascular diseases.
Assuntos
Doenças Cardiovasculares/fisiopatologia , Eletrocardiografia/tendências , Apneia Obstrutiva do Sono/fisiopatologia , Fases do Sono/fisiologia , Adulto , Doenças Cardiovasculares/complicações , Feminino , Voluntários Saudáveis/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Polissonografia/métodos , Apneia Obstrutiva do Sono/complicaçõesRESUMO
Herein, we choose the waste walnut shell as the carbon source, and ammonium heptamolybdate as the molybdenum source to prepare the ß-Mo2C catalyst supported on carbon matrix (Mo2C@C) by the calcination method for hydrogen evolution reaction (HER). The open pores in the porous Mo2C nanoparticle clusters can facilitate electrolyte permeation and hydrogen molecules release as well as the carbon matrix can enhance the conductivity. As a result, the optimal Mo2C exhibits an efficient HER performance, with an overpotential of 140 mV at 10 mA cm-2 and a Tafel slope of 63 mV dec-1 as well as excellent electrochemical stability. The strategy changing waste walnut shell into the effective catalysts sets an example for the searching and designing rational energy materials.
RESUMO
The purpose of this study was to explore the ways in which the Electroencephalogram (EEG) and oxygen saturation (SpO2) are involved in the progressive respiratory restoration process in patients with sleep apnea hypopnea syndrome (SAHS). Twenty-five SAHS patients were enrolled in the analysis. The respiratory events scored from polysomnography (PSG) recordings were divided into two groups as follows: the events followed by secondary events (SREs), which failed to recover stable breathing and those that spontaneously restored stable ventilation (N-SREs). The trends over the course from consecutive respiratory events (CRE) to stable breathing were also analyzed. Higher spectral powers of the δ, θ, and α bands and smaller sample entropy (SampEn) values in the EEG, along with a smaller SpO2 drop were observed in N-SREs, compared to those in SREs. It indicated there are correlations between these conditions and the restoration from respiratory events. The δ band power was the most relevant feature. In the CRE restoring process, the δ, θ, and α powers were significantly increased, while SampEn values exhibited the opposite tendency. Our results may reveal the relationship between EEG activity and respiratory rhythm control.