Detalhe da pesquisa
1.
Telaprevir-based treatment effects on hepatitis C virus in liver and blood.
Hepatology
; 60(6): 1826-37, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24811404
2.
Modeling viral evolutionary dynamics after telaprevir-based treatment.
PLoS Comput Biol
; 10(8): e1003772, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25101970
3.
Genotypic and phenotypic analyses of hepatitis C virus variants observed in clinical studies of VX-222, a nonnucleoside NS5B polymerase inhibitor.
Antimicrob Agents Chemother
; 58(9): 5456-65, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24982088
4.
Hepatitis C virus variants with decreased sensitivity to direct-acting antivirals (DAAs) were rarely observed in DAA-naive patients prior to treatment.
J Virol
; 87(3): 1544-53, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23152524
5.
Evolution of treatment-emergent resistant variants in telaprevir phase 3 clinical trials.
Clin Infect Dis
; 57(2): 221-9, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23575197
6.
Development of a sensitive RT-PCR method for amplifying and sequencing near full-length HCV genotype 1 RNA from patient samples.
Virol J
; 10: 53, 2013 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23402332
7.
Compensatory substitutions in the HCV NS3/4A protease cleavage sites are not observed in patients treated unsuccessfully with telaprevir combination treatment.
Virol J
; 9: 147, 2012 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22866919
8.
VX-222, a non-nucleoside NS5B polymerase inhibitor, in telaprevir-based regimens for genotype 1 hepatitis C virus infection.
Eur J Gastroenterol Hepatol
; 26(7): 761-73, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24901821
9.
Hepatitis C viral evolution in genotype 1 treatment-naïve and treatment-experienced patients receiving telaprevir-based therapy in clinical trials.
PLoS One
; 7(4): e34372, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22511937
10.
Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects.
J Infect Dis
; 198(6): 800-7, 2008 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18637752