Detalhe da pesquisa
1.
Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.
Proc Natl Acad Sci U S A
; 119(46): e2208804119, 2022 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36343253
2.
SAR study of 1,2-benzisothiazole dioxide compounds that agonize HIF-2 stabilization and EPO production.
Bioorg Med Chem
; 77: 117041, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36521398
3.
Structural basis for the allosteric inhibition of hypoxia-inducible factor (HIF)-2 by belzutifan.
Mol Pharmacol
; 2022 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36167425
4.
Current strategies and progress for targeting the "undruggable" transcription factors.
Acta Pharmacol Sin
; 43(10): 2474-2481, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35132191
5.
Dynamics of methane and other greenhouse gases flux in forest ecosystems in China.
J Environ Sci Health A Tox Hazard Subst Environ Eng
; 56(3): 241-247, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33397185
6.
Protective effects of 3ß-angeloyloxy-8ß, 10ß-dihydroxyeremophila-7(11)-en-12, 8α-lactone on paraquat-induced oxidative injury in SH-SY5Y cells.
J Asian Nat Prod Res
; 21(4): 364-376, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29355039
7.
Characterization of a Novel PolyM-Preferred Alginate Lyase from Marine Vibrio splendidus OU02.
Mar Drugs
; 16(9)2018 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30135412
8.
Highly positive-charged zinc(II) phthalocyanine as non-aggregated and efficient antifungal photosensitizer.
Bioorg Med Chem Lett
; 25(11): 2386-9, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25911302
9.
Arctigenin enhances swimming endurance of sedentary rats partially by regulation of antioxidant pathways.
Acta Pharmacol Sin
; 35(10): 1274-84, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25152028
10.
Decoding Allosteric Control in Hypoxia-Inducible Factors.
J Mol Biol
; 436(3): 168352, 2024 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37935255
11.
Sporisorium reilianum polysaccharides improve DSS-induced ulcerative colitis by regulating intestinal barrier function and metabolites.
Int J Biol Macromol
; 265(Pt 1): 130863, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490380
12.
Two natural compounds as potential inhibitors against the Helicobacter pylori and Acinetobacter baumannii IspD enzymes.
Int J Antimicrob Agents
; 63(5): 107160, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38537721
13.
Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-XL by engaging a single-residue discrepancy.
Nat Commun
; 15(1): 1476, 2024 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38368459
14.
Regulation of prostaglandin F2α against ß amyloid clearance and its inflammation induction through LXR/RXR heterodimer antagonism in microglia.
Prostaglandins Other Lipid Mediat
; 106: 45-52, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076168
15.
Synthesis and biological evaluation of arctigenin ester and ether derivatives as activators of AMPK.
Bioorg Med Chem
; 21(13): 3882-93, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23673223
16.
Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.
Nat Commun
; 13(1): 2529, 2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534502
17.
Potential AMPK activators of cucurbitane triterpenoids from Siraitia grosvenorii Swingle.
Bioorg Med Chem
; 19(19): 5776-81, 2011 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21893415
18.
Glaucocalyxin A as a natural product increases amyloid ß clearance and decreases tau phosphorylation involving the mammalian target of rapamycin signaling pathway.
Neuroreport
; 30(4): 310-316, 2019 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30688759
19.
A back-door Phenylalanine coordinates the stepwise hexameric loading of acyl carrier protein by the fatty acid biosynthesis enzyme ß-hydroxyacyl-acyl carrier protein dehydratase (FabZ).
Int J Biol Macromol
; 128: 5-11, 2019 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30677439
20.
Synthesis and evaluation of cytotoxic activities of artemisinin derivatives.
Chem Biol Drug Des
; 90(5): 1019-1028, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28489280