Detalhe da pesquisa
1.
2,2- dimethylbenzopyran derivatives containing pyridone structural fragments as selective dual-targeting inhibitors of HIF-1α and EZH2 for the treatment of lung cancer.
Bioorg Chem
; 147: 107419, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38703440
2.
Synthesis and biological evaluations of 8-biaryl-2,2-dimethylbenzopyranamide derivatives against Alzheimer's disease and ischemic stroke.
Bioorg Chem
; 143: 107064, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38150937
3.
Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic Pain and Lipopolysaccharide-Induced Mortality.
J Med Chem
; 67(3): 2095-2117, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38236416
4.
Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases.
J Med Chem
; 66(4): 2979-3009, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36689364