Detalhe da pesquisa
1.
Population Pharmacokinetic Modeling of Free Plasma and Free Brain Concentrations of Ceftaroline in Healthy and Methicillin-Resistant Staphylococcus aureus-Infected Wistar Rats.
Antimicrob Agents Chemother
; 67(7): e0038223, 2023 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37367389
2.
Population Pharmacokinetic Model of Methotrexate in Brazilian Pediatric Patients with Acute Lymphoblastic Leukemia.
Pharm Res
; 40(7): 1777-1787, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37291462
3.
Population Pharmacokinetic Modeling and Probability of Target Attainment of Ceftaroline in Brain and Soft Tissues.
Antimicrob Agents Chemother
; 66(9): e0074122, 2022 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005769
4.
Preclinical Pharmacokinetic and Pharmacodynamic Investigation of 5'-Methoxynobiletin from Ageratum conyzoides: In vivo and In silico Approaches.
Pharm Res
; 39(9): 2135-2145, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35831672
5.
In vitro pharmacokinetics/pharmacodynamics modeling and efficacy against systemic candidiasis in Drosophila melanogaster of a bisaryloxypropanamine derivative.
Med Mycol
; 59(1): 58-66, 2021 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32407486
6.
Oral clioquinol is effective in the treatment of a fly model of Candida systemic infection.
Mycoses
; 62(5): 475-481, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30600560
7.
Population Pharmacokinetic Modeling to Describe the Total Plasma and Free Brain Levels of Fluconazole in Healthy and Cryptococcus neoformans Infected Rats: How Does the Infection Impact the Drug's Levels on Biophase?
Pharm Res
; 35(7): 132, 2018 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29704215
8.
Fast and sensitive HPLC/UV method for cefazolin quantification in plasma and subcutaneous tissue microdialysate of humans and rodents applied to pharmacokinetic studies in obese individuals.
Biomed Chromatogr
; 32(8): e4254, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-29656496
9.
Influence of Experimental Cryptococcal Meningitis in Wistar Rats on Voriconazole Brain Penetration Assessed by Microdialysis.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28483963
10.
Population Pharmacokinetic Modeling of Etoposide Free Concentrations in Solid Tumor.
Pharm Res
; 33(7): 1657-70, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27068281
11.
Pharmacokinetics of hERG Channel Blocking Voacangine in Wistar Rats Applying a Validated LC-ESI-MS/MS Method.
Planta Med
; 82(11-12): 1030-8, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27257769
12.
Validation of LC-MS/MS method applied to evaluation of free tissue concentrations of vildagliptin in diabetic rats by microdialysis.
Biomed Chromatogr
; 28(12): 1722-7, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24771661
13.
Pharmacokinetic/pharmacodynamic modeling of cortical dopamine concentrations after quetiapine lipid core nanocapsules administration to schizophrenia phenotyped rats.
CPT Pharmacometrics Syst Pharmacol
; 13(4): 638-648, 2024 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38282365
14.
Population pharmacokinetic modeling of the influence of chronic and acute biofilm-forming Pseudomonas aeruginosa lung infection on ciprofloxacin free pulmonary and epithelial lining fluid concentrations.
Eur J Pharm Sci
; 189: 106546, 2023 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37517670
15.
Modeling and Simulation as a Tool to Assess Voriconazole Exposure in the Central Nervous System.
Pharmaceutics
; 15(7)2023 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37513968
16.
Comparison of fluconazole renal penetration levels in healthy and Candida albicans-infected Wistar rats.
Antimicrob Agents Chemother
; 56(11): 5852-7, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22948869
17.
Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review.
Pharmaceutics
; 14(12)2022 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36559157
18.
Correlation between the Skin Permeation Profile of the Synthetic Sesquiterpene Compounds, Beta-Caryophyllene and Caryophyllene Oxide, and the Antiedematogenic Activity by Topical Application of Nanoemulgels.
Biomolecules
; 12(8)2022 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36008995
19.
Probability of Target Attainment of Tobramycin Treatment in Acute and Chronic Pseudomonas aeruginosa Lung Infection Based on Preclinical Population Pharmacokinetic Modeling.
Pharmaceutics
; 14(6)2022 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35745809
20.
Antitubercular Activity of Novel 2-(Quinoline-4-yloxy)acetamides with Improved Drug-Like Properties.
ACS Med Chem Lett
; 13(8): 1337-1344, 2022 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35978694