Detalhe da pesquisa
1.
Cathepsin K inhibitors based on 2-amino-1,3,4-oxadiazole derivatives.
Bioorg Chem
; 109: 104662, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33626452
2.
Experimental and theoretical affinity and catalysis studies between halogenated phenols and peroxidases: Understanding the bioremediation potential.
Ecotoxicol Environ Saf
; 202: 110895, 2020 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32615496
3.
Understanding the Interaction Modes and Reactivity of Trimedoxime toward MmAChE Inhibited by Nerve Agents: Theoretical and Experimental Aspects.
Int J Mol Sci
; 21(18)2020 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32899591
4.
Future Therapeutic Perspectives into the Alzheimer's Disease Targeting the Oxidative Stress Hypothesis.
Molecules
; 24(23)2019 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31816853
5.
Influence of auxochrome group in disperse dyes bearing azo groups as chromophore center in the biotransformation and molecular docking prediction by reductase enzyme: Implications and assessment for environmental toxicity of xenobiotics.
Ecotoxicol Environ Saf
; 160: 114-126, 2018 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29793200
6.
Theoretical Studies Applied to the Evaluation of the DFPase Bioremediation Potential against Chemical Warfare Agents Intoxication.
Int J Mol Sci
; 19(4)2018 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29690585
7.
Assessing the Therapeutic and Toxicological Profile of Novel Acetylcholinesterase Reactivators: Value of In Silico And In Vitro Data.
Curr Med Chem
; 30(36): 4149-4166, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36239718
8.
Combining computational tools and experimental studies towards endocrine disruptors mitigation: A review of biocatalytic and adsorptive processes.
Chemosphere
; 344: 140302, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788749
9.
Silver(I) and Copper(II) 1,10-Phenanthroline-5,6-dione Complexes as Promising Antivirulence Strategy against Leishmania: Focus on Gp63 (Leishmanolysin).
Trop Med Infect Dis
; 8(7)2023 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37505644
10.
Computational evidence for nitro derivatives of quinoline and quinoline N-oxide as low-cost alternative for the treatment of SARS-CoV-2 infection.
Sci Rep
; 11(1): 6397, 2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33737545
11.
Trends in the Recent Patent Literature on Cholinesterase Reactivators (2016-2019).
Biomolecules
; 10(3)2020 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32178264
12.
Asymmetric biodegradation of the nerve agents Sarin and VX by human dUTPase: chemometrics, molecular docking and hybrid QM/MM calculations.
J Biomol Struct Dyn
; 37(8): 2154-2164, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30044197
13.
Anti-Virulence Strategy against the Multidrug-Resistant Bacterial Pathogen Pseudomonas aeruginosa: Pseudolysin (Elastase B) as a Potential Druggable Target.
Curr Protein Pept Sci
; 20(5): 471-487, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30727891
14.
Slight difference in the isomeric oximes K206 and K203 makes huge difference for the reactivation of organophosphorus-inhibited AChE: Theoretical and experimental aspects.
Chem Biol Interact
; 309: 108671, 2019 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31207225
15.
Development of technologies applied to the biodegradation of warfare nerve agents: Theoretical evidence for asymmetric homogeneous catalysis.
Chem Biol Interact
; 308: 323-331, 2019 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31173750
16.
Non-conventional compounds with potential therapeutic effects against Alzheimer's disease.
Expert Rev Neurother
; 19(5): 375-395, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30999771
17.
Disarming Pseudomonas aeruginosa Virulence by the Inhibitory Action of 1,10-Phenanthroline-5,6-Dione-Based Compounds: Elastase B (LasB) as a Chemotherapeutic Target.
Front Microbiol
; 10: 1701, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31428062
18.
Insights into the Drug Repositioning Applied to the Alzheimer's Disease Treatment and Future Perspectives.
Curr Alzheimer Res
; 15(12): 1161-1178, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30101709
19.
Biotransformation of disperse dyes using nitroreductase immobilized on magnetic particles modified with tosyl group: Identification of products by LC-MS-MS and theoretical studies conducted with DNA.
Environ Pollut
; 242(Pt A): 863-871, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30036840
20.
Interactions of cantharidin-like inhibitors with human protein phosphatase-5 in a Mg2+ system: molecular dynamics and quantum calculations.
J Mol Model
; 24(10): 303, 2018 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30280322