Detalhe da pesquisa
1.
Relationship between In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Systemic Tacrolimus Metabolite/Parent Drug Ratio in Renal Transplant Recipients and Healthy Volunteers.
Drug Metab Dispos
; 46(11): 1507-1513, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30166405
2.
Intrarenal resistive index after renal transplantation.
N Engl J Med
; 369(19): 1797-806, 2013 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24195547
3.
Comparative performance of oral midazolam clearance and plasma 4ß-hydroxycholesterol to explain interindividual variability in tacrolimus clearance.
Br J Clin Pharmacol
; 82(6): 1539-1549, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27501475
4.
Progressive decline in tacrolimus clearance after renal transplantation is partially explained by decreasing CYP3A4 activity and increasing haematocrit.
Br J Clin Pharmacol
; 80(3): 548-59, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26114223
5.
Combined effects of CYP3A5*1, POR*28, and CYP3A4*22 single nucleotide polymorphisms on early concentration-controlled tacrolimus exposure in de-novo renal recipients.
Pharmacogenet Genomics
; 24(12): 597-606, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25322286
6.
A highly sensitive liquid chromatography tandem mass spectrometry method for simultaneous quantification of midazolam, 1'-hydroxymidazolam and 4-hydroxymidazolam in human plasma.
Biomed Chromatogr
; 25(10): 1091-8, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21204116
7.
Response to 'Tacrolimus pharmacokinetics after kidney transplantation--Influence of changes in haematocrit and steroid dose'.
Br J Clin Pharmacol
; 80(6): 1473-4, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26235051
8.
Tacrolimus dose requirements and CYP3A5 genotype and the development of calcineurin inhibitor-associated nephrotoxicity in renal allograft recipients.
Ther Drug Monit
; 32(4): 394-404, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20526235
9.
Apparent elevation of cyclosporine whole blood concentrations in a renal allograft recipient.
Ther Drug Monit
; 32(5): 529-31, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20625351
10.
Donor age and renal P-glycoprotein expression associate with chronic histological damage in renal allografts.
J Am Soc Nephrol
; 20(11): 2468-80, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19762492
11.
New insights into the pharmacokinetics and pharmacodynamics of the calcineurin inhibitors and mycophenolic acid: possible consequences for therapeutic drug monitoring in solid organ transplantation.
Ther Drug Monit
; 31(4): 416-35, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19536049
12.
Current target ranges of mycophenolic acid exposure and drug-related adverse events: a 5-year, open-label, prospective, clinical follow-up study in renal allograft recipients.
Clin Ther
; 30(4): 673-83, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18498916
13.
Rhodococcus equi Sepsis in a Renal Transplant Recipient: A Case Study.
Transplant Direct
; 1(3): e11, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27500216
14.
Impact of CYP3A5 genotype on tacrolimus versus midazolam clearance in renal transplant recipients: new insights in CYP3A5-mediated drug metabolism.
Pharmacogenomics
; 14(12): 1467-80, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24024898
15.
The once-daily formulation of tacrolimus: a step forward in kidney transplantation?
Transplantation
; 93(3): 241-3, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22234346
16.
The P450 oxidoreductase *28 SNP is associated with low initial tacrolimus exposure and increased dose requirements in CYP3A5-expressing renal recipients.
Pharmacogenomics
; 12(9): 1281-91, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21770725
17.
A prospective, open-label, observational clinical cohort study of the association between delayed renal allograft function, tacrolimus exposure, and CYP3A5 genotype in adult recipients.
Clin Ther
; 32(12): 2012-23, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21118736
18.
Reduced C0 concentrations and increased dose requirements in renal allograft recipients converted to the novel once-daily tacrolimus formulation.
Transplantation
; 90(5): 523-9, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20592652
19.
Cutaneous phaeohyphomycosis in renal allograft recipients: report of 2 cases and review of the literature.
Diagn Microbiol Infect Dis
; 68(2): 177-80, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20846592
20.
Calcium metabolism in the early posttransplantation period.
Clin J Am Soc Nephrol
; 4(3): 665-72, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19261823