Detalhe da pesquisa
1.
Development of pyridyl thiosemicarbazones as highly potent agents for the treatment of malaria after oral administration.
J Antimicrob Chemother
; 74(10): 2965-2973, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31325302
2.
UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.
Antimicrob Agents Chemother
; 62(9)2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941635
3.
Synthesis of five libraries of 6,5-fused heterocycles to establish the importance of the heterocyclic core for antiplasmodial activity.
Bioorg Med Chem
; 26(21): 5730-5741, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30391094
4.
Synthesis and biological characterisation of ester and amide derivatives of fusidic acid as antiplasmodial agents.
Bioorg Med Chem Lett
; 27(3): 658-661, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28012840
5.
Design, synthesis, and In vitro antituberculosis activity of 2(5H)-Furanone derivatives.
IUBMB Life
; 68(8): 612-20, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27346745
6.
Identification of New Human Malaria Parasite Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors by Pharmacophore and Structure-Based Virtual Screening.
J Chem Inf Model
; 56(3): 548-62, 2016 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26915022
7.
Alpha-glucosidase inhibitory and antiplasmodial properties of terpenoids from the leaves of Buddleja saligna Willd.
J Enzyme Inhib Med Chem
; 31(1): 63-6, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-25694064
8.
In vitro antiplasmodial activity of triazole-linked chloroquinoline derivatives synthesized from 7-chloro-N-(prop-2-yn-1-yl)quinolin-4-amine.
Bioorg Med Chem
; 23(15): 4163-4171, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26174655
9.
Syntheses and in Vitro Antiplasmodial Activity of Aminoalkylated Chalcones and Analogues.
J Nat Prod
; 78(8): 1848-58, 2015 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26235033
10.
Synthesis and biological evaluation of 2-aminothiazole derivatives as antimycobacterial and antiplasmodial agents.
Bioorg Med Chem Lett
; 24(2): 560-4, 2014 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24373723
11.
Synthesis of halogenated 4-quinolones and evaluation of their antiplasmodial activity.
Bioorg Med Chem Lett
; 24(4): 1214-7, 2014 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24468411
12.
Synthesis of novel triazole-linked mefloquine derivatives: biological evaluation against Plasmodium falciparum.
Bioorg Med Chem Lett
; 24(23): 5466-9, 2014 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25455485
13.
Erratum for Brunschwig et al., "UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria".
Antimicrob Agents Chemother
; 62(11)2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30355750
14.
Synthesis, characterization and antimalarial activity of quinoline-pyrimidine hybrids.
Bioorg Med Chem
; 21(1): 269-77, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23168082
15.
Synthesis and evaluation of hybrid drugs for a potential HIV/AIDS-malaria combination therapy.
Bioorg Med Chem
; 20(17): 5277-89, 2012 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22858300
16.
Antiplasmodial and antibacterial activity of compounds isolated from Ormocarpum trichocarpum.
Planta Med
; 78(17): 1857-60, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23059633
17.
Age Estimate of GJB2-p.(Arg143Trp) Founder Variant in Hearing Impairment in Ghana, Suggests Multiple Independent Origins across Populations.
Biology (Basel)
; 11(3)2022 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35336849
18.
Antiplasmodial and antimycobacterial activities of crude and lead-like enhanced extracts from Namibian medicinal plants.
J Ethnopharmacol
; 295: 115389, 2022 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35589021
19.
Cell-based analysis of CLIC5A and SLC12A2 variants associated with hearing impairment in two African families.
Front Genet
; 13: 924904, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36035115
20.
GJB2 Is a Major Cause of Non-Syndromic Hearing Impairment in Senegal.
Biology (Basel)
; 11(5)2022 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35625523