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1.
Med Educ ; 57(6): 587-594, 2023 06.
Artigo em Inglês | MEDLINE | ID: mdl-36572953

RESUMO

INTRODUCTION: Various initiatives to improve access to health care have been implemented internationally. In Brazil, this has included policies intended to expand access to higher education for underrepresented socio-economic groups. These measures have reduced inequalities in access to medical education, but it is not known whether they influence career choices. We examine the effect of these educational policies on physician practice patterns in primary care and/or in medically underserved areas. METHODS: This is a cross-sectional study that analysed the association between affirmative educational policies and the career choices of physicians who graduated between 2010 and 2015. Multivariate binary regression analysis was used to evaluate the impact of affirmative educational policies on physician career choices, including primary care practice, practice in cities with ≤20 000 inhabitants, and practice in less developed municipalities 4 years after graduation. RESULTS: We identified the practice patterns of 65 304 (82.8%) physicians 4 years after their graduation. Most physicians included in our analysis were female (54.5%), aged ≤27 years (72.4%), born in developed cities and studied in private medical schools. Physicians admitted to medical school based on racial or social access policies were more likely to practice in municipalities with fewer than 20 000 inhabitants (odds ratio [OR]: 1.64; 1.36-1.98) and in primary care (OR: 1.55; 1.35-1.53). Physicians who benefited from scholarships for under-represented socio-economic groups were more likely to practice in small cities (OR: 1.24; 1.07-1.43) and primary care (OR: 1.23; 1.11-1.37). The provision of financial aid also improved the likelihood of practice in primary care and underserved areas. Graduation from medical schools located in smaller cities was associated with practice in municipalities ≤20 000 inhabitants and primary care. CONCLUSIONS: Our results demonstrated that educational policies implemented in the Brazilian context are effective in reducing inequities in physician distribution and led to an increase in the number of physicians practicing in primary care.


Assuntos
Médicos , Humanos , Feminino , Masculino , Estudos Transversais , Brasil , Escolha da Profissão , Área Carente de Assistência Médica , Políticas , Acessibilidade aos Serviços de Saúde
2.
Clin Oral Investig ; 27(11): 6471-6482, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37718381

RESUMO

OBJECTIVE: To analyze the clinical and microbiological efficacy of antimicrobial photodynamic therapy (aPDT) in patients with erythematous candidiasis (EC). METHODS: This study was a controlled and randomized clinical trial in patients diagnosed with EC, who were allocated into a control group (CG) and experimental group (EG) treated with nystatin oral suspension and aPDT with methylene blue 0.1%, respectively. A clinical index was used to classify the EC lesions from mild to severe and assess the treatment efficacy. Microbiological samples were collected before and after aPDT session and analyzed by counting colony-forming units (CFUs) of Candida and Staphylococcus sp. RESULTS: A total of 41 patients (CG (n = 18); EG (n = 23)) were analyzed in our research. Of these, 16 (94.1%) of the CG and 16 (84.2%) of the EG exhibited complete remission of the lesions. Regarding the degree of the lesion, it was observed that the severe lesions were more difficult to present remission, while all the mild and moderate lesions showed complete regression (p = 0.001). The microbiological analysis showed that Candida albicans and Staphylococcus sp. were the most prevalent microorganisms, and the aPDT group showed a decrease in CFUs of these microorganisms after the first aPDT session (p < 0.05). CONCLUSIONS: aPDT proved to be a clinically and microbiologically effective therapy for treating EC. TRIAL REGISTRATION: Registered at ClinicalTrials.gov; Set 12th, 2019; No. RBR-8w8599. CLINICAL RELEVANCE: aPDT is a promising alternative treatment since it presents satisfactory results and does not cause damage to oral tissues or develop resistance to the treatment.


Assuntos
Anti-Infecciosos , Candidíase Bucal , Fotoquimioterapia , Humanos , Anti-Infecciosos/uso terapêutico , Candida albicans , Candidíase Bucal/tratamento farmacológico , Azul de Metileno , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes
3.
Lasers Med Sci ; 37(3): 1945-1952, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34787762

RESUMO

Our study aimed to study the efficacy of ILIB on periodontal parameters and glycemic control in patients with periodontitis and type II diabetes. Twenty-one patients in a randomized clinical trial were divided into 2 groups: control group (CG), conventional periodontal therapy, and test group (TG), conventional periodontal treatment associated with 10 laser applications by the ILIB-Modified (ILIB-M) technique. Fasting blood glucose levels and glycated hemoglobin (HbA1c), visible plaque index (VPI), gingival bleeding index (GBI), and periodontal clinical parameters were evaluated at baseline and after 4 months (T4). Regarding periodontal parameters, the intragroup analysis showed a statistically significant reduction (p < 0.05) between baseline and T4, for the VPI, GBI, BOP, PD, and CAL indexes. However, in the intergroup analysis, no statistically significant improvements (p > 0.05) were observed between the TG and CG for the VPI, GBI, BOP, PD, and CAL indexes. Regarding HbA1C and fasting blood glucose values, no statistically significant improvements were observed in intergroup and intragroup analyses (p > 0.05). The Modified ILIB did not improve the periodontal clinical parameters and glycemic control in patients with type II diabetes.


Assuntos
Periodontite Crônica , Diabetes Mellitus Tipo 2 , Periodontite Crônica/complicações , Periodontite Crônica/terapia , Raspagem Dentária , Diabetes Mellitus Tipo 2/complicações , Hemoglobinas Glicadas , Controle Glicêmico , Humanos , Aplainamento Radicular/métodos
4.
Eur Arch Otorhinolaryngol ; 278(4): 1223-1231, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32696249

RESUMO

PURPOSE: The aim of the present study was to evaluate the 5-year recurrence-free survival and prognostic factors of odontogenic keratocyst (OKC) from a single-center retrospective cohort in the northeastern region of Brazil. METHODS: Forty cases of OKC comprised the study population. In the cohort analyzed, 18 (45%) cases were recurrent OKCs and 22 (55%) were non-recurrent OKCs. Recurrence-free survival was defined as the period from the release of the histopathological report to the occurrence of relapse or last visit to the service. RESULTS: Comparison of the clinicopathological variables between primary and recurrent OKC lesions revealed no differences in the frequency of epithelial thickness, presence of satellite cysts and cystic spaces, presence of an inflammatory infiltrate, locularity, and lesion borders. The frequency of symptoms was practically the same even after recurrence. Satellite cysts were more frequent in the group of recurrent lesions (n = 9, p = 0.002) and the presence of an inflammatory infiltrate was also significantly associated with recurrent lesions (n = 15, p = 0.006). Previous decompression or marsupialization was associated with recurrence of the lesion (p = 0.010). CONCLUSIONS: In conclusion, the most significant prognostic factors were previous decompression or marsupialization, as well as, morphological parameters associated with the recurrence cases were the presence of an inflammatory infiltrate and satellites cysts. The risk of recurrence is low but continues due to the particularities of epithelial proliferation in OKC.


Assuntos
Recidiva Local de Neoplasia , Cistos Odontogênicos , Brasil , Humanos , Cistos Odontogênicos/epidemiologia , Cistos Odontogênicos/cirurgia , Prognóstico , Estudos Retrospectivos
5.
Trop Med Int Health ; 25(12): 1510-1521, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-32959943

RESUMO

OBJECTIVE: The objective of this study was to analyse abundance and spatial distribution of Aedes aegypti and Aedes albopictus oviposition in the city of Natal-RN, 2016 to 2018. METHODS: Three hundred and seven oviposition traps were installed covered the whole city and were monitored weekly from January 2016 to December 2018. To verify the abundance of the vector based on its location, the formation of oviposition clusters was studied using the Kernel statistics. Egg Density Index (EDI) and Oviposition Positivity Index (OPI) values were calculated. RESULTS: Temperature and humidity presented weak and very weak correlation, respectively, with the oviposition indicators. The median of oviposition positivity index (OPI) was 60.5%, and the egg density index (EDI) was 45.4 eggs/trap. The OPI (71.1%) was higher in the second quarter of the year. The areas with the most persistent oviposition are located in a continuous strip that extends from the extreme of the northern district and extends along the western district of the city. Also noteworthy is the proximity to the strategic points. CONCLUSION: The spatio-temporal distribution of oviposition revealed that there is spatial segregation and marked seasonality. Therefore, this study highlights the importance of maintaining surveillance targeting and control strategies focused on these areas, especially during the most important period of the year.


OBJECTIF: L'objectif de cette étude était d'analyser l'abondance et la distribution spatiale de la ponte d'Aedes aegypti et d'Aedes albopictus dans la ville de Natal-RN, de 2016 à 2018. MÉTHODES: 307 pièges de ponte ont été installés dans toute la ville et surveillés chaque semaine de janvier 2016 à décembre 2018. Pour vérifier l'abondance du vecteur en fonction de sa localisation, la formation de grappes de ponte a été étudiée à l'aide des statistiques de Kernel. Les valeurs de l'indice de densité des œufs (IDO) et de l'indice de positivité de la ponte(IPP) ont été calculées. RÉSULTATS: La température et l'humidité ont présenté une corrélation faible et très faible, respectivement, avec les indicateurs de ponte. L'indice médian de positivité de ponte (IPP) était de 60,5% et l'indice de densité des œufs (IDO) était de 45,4 œufs/piège. L'IPP (71,1%) était plus élevé au deuxième trimestre de l'année. Les zones avec la ponte la plus persistante sont situées dans une bande continue qui s'étend de l'extrémité du district nord et s'étend le long du district ouest de la ville. A noter également la proximité des points stratégiques. CONCLUSIONS: La distribution spatiotemporelle de la ponte a révélé une ségrégation spatiale et une saisonnalité marquée. Par conséquent, cette étude met en évidence l'importance de maintenir des stratégies de surveillance ciblée et de contrôle axés sur ces zones, en particulier pendant la période la plus importante de l'année.


Assuntos
Aedes/fisiologia , Oviposição/fisiologia , Estações do Ano , Animais , Brasil , Cidades , Feminino , Umidade , Mosquitos Vetores , Análise Espaço-Temporal , Temperatura
6.
Am J Orthod Dentofacial Orthop ; 157(1): 42-48.e2, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31901279

RESUMO

INTRODUCTION: Orthodontic treatments are performed to improve esthetics and masticatory functions. In general, clinical criteria are used to recommend such treatments without considering the opinion of the patient. This study aimed to evaluate the relationship between technically defined orthodontic need (normative criteria) and the need for treatment perceived by adolescent patients. METHODS: A total of 215 students aged between 15 and 19 years were selected and asked to respond to a questionnaire concerning their perception of need for orthodontic treatment and their satisfaction with their own esthetics and mastication. One trained and calibrated examiner obtained normative data using the Dental Aesthetic Index (DAI) on the need for orthodontic treatment of these students. RESULTS: Associations were found between the DAI score and the patient's perception of need for orthodontic treatment (P <0.001), satisfaction with esthetics (P = 0.003), and satisfaction with mastication (P = 0.047). When occlusal characteristics were analyzed separately, associations between several normative and perceived needs, as well as for satisfaction with esthetics, were found. Satisfaction with mastication analysis was only found to be associated with open bite malocclusion (P = 0.003). CONCLUSIONS: The DAI revealed a consistent opinion in adolescents to link their perceived malocclusion-related conditions to esthetics.


Assuntos
Má Oclusão , Satisfação Pessoal , Adolescente , Estética , Humanos , Mastigação , Adulto Jovem
7.
BMC Oral Health ; 17(1): 5, 2016 Jul 04.
Artigo em Inglês | MEDLINE | ID: mdl-27430364

RESUMO

BACKGROUND: Brazil has severe socioeconomic inequalities, resulting in major oral health problems for the Brazilian elderly, such as tooth loss and, consequently, a need for oral rehabilitation. The aim of this study was to evaluate inequalities in complete denture need among older Brazilian adults in relation to social determinants at individual and contextual levels. METHODS: This retrospective study was based on data from the national oral health survey, SB Brasil 2010, in which 7,619 older adults aged 65-74 years participated. The dependent variable was complete denture need. The independent variables at the first level were age, sex, race, and socioeconomic status. The independent variables that were used to identify inequality at the contextual level were geographic region of Brazil, the population of the municipality where the subject lived, whether the subject lived in the state capital or not, and the Human Development Index. In order to describe the socioeconomic characteristics, a socioeconomic cluster variable was created using the multivariable cluster analysis technique. Prevalence ratios (PRs) with 95 % confidence intervals (CIs) were determined to evaluate the effect of each variable. Two-level multivariable modeling was performed to examine the individual and contextual effects. RESULTS: There was a high prevalence of complete denture need among older Brazilian adults. The main factors associated with the prevalence of complete denture need were individual socioeconomic status (PR: 1.81; 95 % CI: 1.65-1.99), and the city-level contextual effect (PR: 1.20; 95 % CI: 1.08-1.34). CONCLUSIONS: Consistently poor rates of oral health rehabilitation were found among older Brazilian adults, and were associated with significant social inequality. Complete denture need was strongly associated with individual socioeconomic position. It was also verified that the Human Development Index, the city-level contextual effect, was associated with complete denture need.


Assuntos
Prótese Total , Disparidades em Assistência à Saúde , Saúde Bucal , Fatores Socioeconômicos , Idoso , Brasil , Estudos Transversais , Feminino , Humanos , Masculino , Estudos Retrospectivos
8.
Eur Arch Otorhinolaryngol ; 272(10): 2601-9, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25149291

RESUMO

Voice disorders can occur in the elderly as a result of natural anatomical and physiological changes or greater exposure to pathological conditions in the aging, affecting communication and quality of life. Nevertheless, data about the prevalence of voice disorders in this phase of life are not well known in a population-based perspective. The aim of the present systematic review was to identify the prevalence of vocal disorders in persons aged 60 years or more in population-based studies. A systematic review was undertaken in eleven electronic databases based on preferred reporting items for systematic reviews and meta-analysis statement (PRISMA) criteria. The methodological quality of the studies was analyzed with strengthening the reporting of observational studies in epidemiology (STROBE) directives. The search was conducted independently by two researchers. Four articles satisfied the criteria of eligibility. The prevalence of vocal disorders in the general population aged 60 years or more ranged from 4.8 to 29.1%. The studies were different in terms of the methodological procedures and the STROBE directives were not completely satisfied by any of the articles selected. The prevalence of vocal disorders in the general elderly population ranged from low to moderate in population-based studies. The methodological discrepancies of the studies compromised the reliability of the estimated data. Upgrading the methodological quality of studies and designing a short, valid and easy-to-use functional voice-related instrument are urgently required in health surveys to determine the prevalence of vocal disorders among elderly individuals.


Assuntos
Envelhecimento , Vigilância da População , Distúrbios da Voz/epidemiologia , Fatores Etários , Idoso , Saúde Global , Humanos , Prevalência , Reprodutibilidade dos Testes
9.
Int Dent J ; 65(6): 331-7, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26397722

RESUMO

OBJECTIVE: The aim of the present study was to evaluate the influence of oral conditions in preschool children and associated factors on work absenteeism experienced by parents or guardians. METHODS: A preschool-based, cross-sectional study was conducted of 837 children, 3-5 years of age, in Campina Grande, Brazil. Parents or guardians answered the Brazilian version of the Early Childhood Oral Health Impact Scale. The item 'taken time off work' was the dependent variable. Questionnaires addressing sociodemographic variables, history of toothache and health perceptions (general and oral) were also administered. Clinical examinations for dental caries and traumatic dental injury (TDI) were performed by three dentists who had undergone training and calibration exercises. Cohen's kappa (κ) was 0.83-0.88 for interexaminer agreement and 0.85-0.90 for intra-examiner agreement. Descriptive, analytical statistics were conducted, followed by logistic regression for complex samples (α = 5%). RESULTS: The prevalence of parents' or guardians' work absenteeism because of the oral conditions of their children was 9.2%. The following variables were significantly associated with work absenteeism: mother's low schooling [odds ratio (OR) = 2.31; 95% confidence interval (95% CI): 1.31-4.07]; history of toothache (OR = 6.33; 95% CI: 3.18-12.61); and avulsion or luxation types of TDI (OR = 8.54; 95% CI: 1.80-40.53). CONCLUSION: Other oral conditions that do not generally cause pain, such as dental caries with a low degree of severity or inactive dental caries and uncomplicated TDI, were not associated with parents' or guardians' work absenteeism of preschool children. It is concluded that toothache, avulsion, luxation and a low degree of mother's schooling are associated with work absenteeism.


Assuntos
Absenteísmo , Saúde Bucal , Pais , Trabalho , Fatores Etários , Atitude Frente a Saúde , Brasil/epidemiologia , Saúde da Criança , Pré-Escolar , Estudos Transversais , Cárie Dentária/epidemiologia , Escolaridade , Saúde da Família , Feminino , Nível de Saúde , Humanos , Renda , Masculino , Pais/psicologia , Qualidade de Vida , Avulsão Dentária/epidemiologia , Traumatismos Dentários/epidemiologia , Odontalgia/epidemiologia
10.
Gerodontology ; 30(2): 141-9, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22607365

RESUMO

OBJECTIVE: Identify factors associated with missing teeth in the elderly institutionalised population in Brazil. METHODOLOGY: Cross-sectional study of elderly institutionalised Brazilians with 1192 subjects. A questionnaire was applied as well as an epidemiological survey of oral health conditions in accordance with WHO. Factorial analysis was carried out with variables related to missing teeth, as well as the Fisher's exact test, chi-squared test and multiple logistic regression. RESULTS: Mean age was 76.3 (± 9.8), 53.5% (638) of subjects were women and 717 (60.2) were dependent. Mean of Decayed Missing and Filled Teeth Index (DMFT index) was 29.4 (± 4.9). The subjects that did not use upper and lower dentures were 61.5% (732) and 79.2% (944), respectively. Median number of missing teeth per person was 27.88 (± 6.8) with a mean of 4 (± 6.6) teeth present and 2.4 (± 4.5) caries-free teeth. Factors associated with missing teeth following multivariate analysis were: age, sex, self-assessment of oral health, access to health services, type of institution and area of the country. CONCLUSIONS: High level of tooth loss and low level of rehabilitation demonstrate precarious oral health. It is therefore necessary to improve institutional access mechanisms to public health facilities for the institutionalised elderly.


Assuntos
Institucionalização/estatística & dados numéricos , Perda de Dente/epidemiologia , Fatores Etários , Idoso , Atitude Frente a Saúde , Brasil/epidemiologia , Estudos Transversais , Índice CPO , Assistência Odontológica/estatística & dados numéricos , Cárie Dentária/epidemiologia , Restauração Dentária Permanente/estatística & dados numéricos , Prótese Total Inferior/estatística & dados numéricos , Prótese Total Superior/estatística & dados numéricos , Estudos Epidemiológicos , Feminino , Avaliação Geriátrica/estatística & dados numéricos , Humanos , Arcada Parcialmente Edêntula/epidemiologia , Masculino , Pessoa de Meia-Idade , Avaliação das Necessidades/estatística & dados numéricos , Doenças Periodontais/epidemiologia , Fatores Sexuais , Extração Dentária/estatística & dados numéricos , Saúde da População Urbana/estatística & dados numéricos
11.
Med Oral Patol Oral Cir Bucal ; 18(2): e285-92, 2013 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-23385501

RESUMO

OBJECTIVE: The objective of this study is to describe the oral health status and the factors associated with oral health-related quality of life (OHRQoL) in people aged 65 and older institutionalized in Barcelona in 2009. STUDY DESIGN: [corrected] Cross sectional study in 194 elderly. The dependent variable was poor OHRQoL, according to the Geriatric Oral Health Assessment Index (GOHAI). The independent variables were socio-demographic data, last dental visit, subjective and objective oral health status. Robust Poisson regression analysis was used to determine the factors associated with OHRQoL as well as the strengths of association (Prevalence Ratios with respective confidence intervals at 95%). RESULTS: According to GOHAI, 94 women (68.1%) and 36 men (64.3%) had poor OHRQoL. The average DMFT index (number of decayed, missing and filled teeth) was 22.8, with mean 10.2 remaining teeth. According to the Community Periodontal Index only 1.9% were healthy. 33.8% of the sample (35.5% of women and 30.4% of men) presented edentulism, 54.2% needed upper dental prostheses (51.1% of women and 60.7% of men) and 64.7% needed lower ones (61.6% of women and 71.4% of men). Only 7.2% had visited a dentist in the past year (8.8% of women and 3.6% of men). After fitting several multivariate adjusted robust Poisson regression models, poor OHRQoL was found to be associated to self-reporting problems with teeth or gums, self-reporting poor opinion about teeth/gums/denture and also associated to functional edentulism, needing upper denture, but not to socio-demographic factors or time since last dental visit. CONCLUSIONS: The study population has poor objective oral health. A high percentage has poor OHRQoL associated to subjective and objective oral health conditions. Dental care is required and these services should be included in the Spanish National Health System.


Assuntos
Institucionalização , Saúde Bucal , Qualidade de Vida , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Espanha
12.
PLoS One ; 18(1): e0280541, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36662788

RESUMO

BACKGROUND: Weight measurement is important in the nutritional anthropometric monitoring of older adults. When this measurement is not possible, estimates may be used. AIM: Developing and validating weight predictive equations for older adult residents in long-term care institutions in Brazil. SUBJECTS AND METHODS: The sample comprised 393 older adult residents in long-term care institutions. Data were collected in two stages, with 315 older adults in the first and 78 in the second. We have measured the arm, calf, and waist circumferences, as well as the triceps and subscapular skinfold and knee height. Multiple linear regression was used to develop the equations, which were evaluated through the coefficient of determination, standard error of estimation, Akaike information criterion, intraclass correlation coefficient (ICC), and Bland-Altmann plot. RESULTS: Five models with different anthropometric measurements were developed, (1) arm circumference as a discriminant variable (ICC: 0.842); (2) best statistical fit for men and women (ICC: 0.874) and its stratification by sex (3) (ICC: 0.876); (4) easy-to-perform measurement for men and women (ICC: 0.842) and its stratification by sex (5) (ICC: 0.828). CONCLUSION: Five models for estimating the weight of older adult residents in long-term care institutions were developed and validated. The choice to use the models should be based on the physical capacity of the older adults to be evaluated.


Assuntos
Tecido Adiposo , Assistência de Longa Duração , Masculino , Humanos , Feminino , Idoso , Brasil , Antropometria , Modelos Lineares
13.
Arch Gerontol Geriatr ; 101: 104702, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35413609

RESUMO

OBJECTIVE: To analyze the trajectory of changes in mobility during walking (i.e., maintenance and recovery) of institutionalized older adults and verify the incidence and risk factors for mobility decline. METHODS: A two-year longitudinal prospective study was conducted with 358 participants aged ≥ 60 years and institutionalized in ten nursing homes in Natal-RN (Brazil). Mobility was assessed using the "walking" item of the Barthel index. Sociodemographic, institution-related, and health-related variables were considered at baseline. Poisson regression was used to build a multiple model. RESULTS: The incidence of mobility decline during walking was 10.6% (95% confidence interval [95% CI] = 7.4 to 13.8) after 12 months and 37.7% (95% CI = 18.0 to 26.6) after 24 months. Age ≥ 83 years (relative risk = 1.58; 95% CI = 1.24 to 2.02; p < 0.001) and hospitalization (relative risk = 3.16; 95% CI = 1.55 to 6.45; p = 0.002) were predictors of mobility decline. The rate of mobility maintenance was 31.8% after 12 months (95% CI = 31.8 to 42.9) and 23.2% after 24 months (95% CI = 26.8 to 38.5). Also, the rate of recovery was 2.5% (95% CI = 1.0 to 5.0) and 1% (95% CI = 0.2 to 2.6) after 12 and 24 months, respectively. CONCLUSION: The trajectory of mobility during walking of institutionalized older adults in northeastern Brazil was dynamic (i.e., increasing incidence of mobility decline after 24 months) and associated with advanced age and hospitalization. The chances of recovering walking performance are minimal, and maintenance of independent mobility is challenging.


Assuntos
Limitação da Mobilidade , Caminhada , Idoso , Humanos , Incidência , Estudos Longitudinais , Estudos Prospectivos , Fatores de Risco
14.
PLoS One ; 17(11): e0276931, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36318578

RESUMO

The effects of congenital Zika syndrome (CZS) on the tooth development of infected children are not well known. The aim of this study was to analyze the association of CZS with dental alterations in children with microcephaly seen at a referral hospital in Rio Grande do Norte, Brazil. The chronology and sequence of tooth eruption and the presence of dental alterations were evaluated by a single calibrated examiner (kappa > 0.80) in 62 children aged 7 to 35 months with microcephaly associated with CZS and other congenital infections. Medical data of the mother and child were collected from the records and the parents responded to a socioeconomic questionnaire. Descriptive analysis and Fisher's exact test were used (5% significance level). The mean age of the children was 26.4 months (SD = 7.52). The mean weight and head circumference at birth were 2,593 g (SD = 0.60) and 29.6 cm (SD = 2.48), respectively. Microcephaly was associated with congenital Zika virus infection in 79% of cases and with other congenital infections in 21%. No significant association was found between CZS and alterations in the chronology (p = 1.00) or sequence of tooth eruption (p = 0.16) or changes in enamel development (p = 1.00). In conclusion, children with microcephaly exhibit a delay and alterations in the sequence of tooth eruption of primary teeth, as well as developmental defects of enamel, which are not associated with Zika virus infection.


Assuntos
Microcefalia , Complicações Infecciosas na Gravidez , Anormalidades Dentárias , Infecção por Zika virus , Zika virus , Recém-Nascido , Criança , Feminino , Humanos , Pré-Escolar , Gravidez , Infecção por Zika virus/complicações , Brasil , Mães
15.
Head Neck Pathol ; 15(3): 955-966, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33394370

RESUMO

Odontomas and ameloblastic fibro-odontomas (AFOs) are the result of a developmental anomaly of odontogenic tissues. A literature review of proteins immunoexpressed in odontomas and AFOs was conducted in order to determine which proteins are involved in the pathogenesis of these lesions. AFO was changed to early odontoma in the 2017 WHO classification and will also be discussed in this article. A literature search was performed in the following electronic databases: PubMed/MEDLINE, Web of Science, Scopus, EMBASE, Lilacs, Cochrane Collaboration Library, and Science Direct. The research question was developed according to the population, intervention, comparison, and outcome (PICO) framework: Which proteins are related to the differentiation of odontomas and what is their interrelationship with AFOs? Thirty articles met all inclusion criteria and were selected for this systematic review, totaling 355 cases of odontomas and 43 cases of AFO. Similar immunoexpression was observed in odontomas and AFOs. Immunoexpression of proteins involved in cell differentiation was higher in compound odontomas than in complex odontomas. Proteins involved in histodifferentiation and enamel formation were more frequent in odontomas. The immunoexpression of enamel matrix proteins differs between odontomas and tooth germs, with their persistence being related to the development of odontomas. Compound odontomas exhibit the highest immunoexpression of proteins involved in cellular histodifferentiation and the Wnt/beta-catenin pathway is involved in tumor formation.


Assuntos
Odontoma/metabolismo , Odontoma/patologia , Animais , Humanos , Odontogênese/fisiologia , Proteômica
16.
Trans R Soc Trop Med Hyg ; 115(9): 1010-1018, 2021 09 03.
Artigo em Inglês | MEDLINE | ID: mdl-33547898

RESUMO

BACKGROUND: Currently syphilis is considered an epidemic disease worldwide. The objective of this study was to identify intra-urban differentials in the occurrence of congenital and acquired syphilis and syphilis in pregnant women in the city of Natal, in northeast Brazil. METHODS: Cases of syphilis recorded by the municipal surveillance system from 1 January 2011 to 30 December 2018 were analysed. Spatial statistical analyses were performed using the kernel density estimator of the quadratic smoothing function (weighted). SaTScan software was applied for the calculation of risk based on a discrete Poisson model. RESULTS: There were 2163 cases of acquired syphilis, 738 cases of syphilis in pregnant women and 1279 cases of congenital syphilis. Kernel density maps showed that the occurrence of cases is more prevalent in peripheral areas and in areas with more precarious urban infrastructure. In 2011-2014 and 2015-2018, seven statistically significant clusters of acquired syphilis were identified. From 2011 to 2014, the most likely cluster had a relative risk of 3.54 (log likelihood ratio [LLR] 38 895; p<0.001) and from 2015 to 2018 the relative risk was 0.54 (LLR 69 955; p<0.001). CONCLUSIONS: In the municipality of Natal, there was a clustered pattern of spatial distribution of syphilis, with some areas presenting greater risk for the occurrence of new cases.


Assuntos
Complicações Infecciosas na Gravidez , Sífilis Congênita , Sífilis , Brasil/epidemiologia , Feminino , Humanos , Gravidez , Complicações Infecciosas na Gravidez/epidemiologia , Gestantes , Sífilis/epidemiologia , Sífilis Congênita/epidemiologia
17.
Am J Dent ; 23(6): 311-6, 2010 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-21344828

RESUMO

PURPOSE: To evaluate the efficacy of conservative treatment of dentin non-cavitated caries using a resin-based fluoride-containing pit and fissure sealant. METHODS: In this controlled clinical trial, 60 teeth with clinically non-cavitated occlusal caries radiographically located beneath the enamel-dentin junction (radiolucent area) were selected among patients presenting a moderate to high caries risk. The teeth were randomly divided into two groups of 30 teeth each: an experimental group receiving an application of Fluorshield (Dentsply) sealant and a control group not submitted to any clinical intervention. Caries progression was monitored by clinical and radiographic examination at 4-month intervals over a period of 1 year. In addition, marginal integrity of the sealant was evaluated in the experimental group. RESULTS: Clinical and radiographic caries progression was significantly more frequent in control teeth when compared to the experimental group (P < 0.05).


Assuntos
Cárie Dentária/prevenção & controle , Selantes de Fossas e Fissuras/uso terapêutico , Adolescente , Distribuição de Qui-Quadrado , Criança , Cárie Dentária/diagnóstico por imagem , Dentina/patologia , Feminino , Humanos , Masculino , Dente Molar , Radiografia , Método Simples-Cego , Estatísticas não Paramétricas , Adulto Jovem
18.
Oral Health Prev Dent ; 8(2): 153-8, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20589249

RESUMO

PURPOSE: The objective of the present study was to determine the prevalence of xerostomia (dry mouth sensation) and hyposalivation in elderly type-2 diabetic individuals and to establish whether such conditions might be associated with their socioeconomic status and/or medical and oral health conditions. MATERIALS AND METHODS: The present cross-sectional study included 315 functionally independent elderly individuals, aged 60 years or above, residing in Natal, northeastern Brazil. A total of 52 subjects self-reported to be diabetic. The data on the subjects' health condition were collected using a questionnaire, performing a physical examination and sialometry (unstimulated and stimulated whole saliva flow rates), and the variables were subjected to descriptive statistics, chi-square and Student t test (a = 0.05). RESULTS: The prevalence of dry mouth was found to be 25%. Hyposalivation was found in 48% and 46% of the subjects in unstimulated and stimulated conditions, respectively. The only factor that was associated with xerostomia among the diabetics was workplace (P = 0.01), suggesting that elderly diabetics working at home might be less likely to have dry mouth than those working outside. No variable assessed was associated with hyposalivation, in either unstimulated or stimulated salivary flow. CONCLUSIONS: The prevalence of dry mouth and hyposalivation was high in elderly diabetics. Only at-home jobs were observed to be associated with dry mouth. There was no association between hyposalivation and the variables assessed, with regard to either unstimulated or stimulated saliva. Further studies, involving larger samples, are required to confirm the present findings.


Assuntos
Diabetes Mellitus Tipo 2/complicações , Xerostomia/complicações , Idoso , Brasil/epidemiologia , Estudos Transversais , Dentaduras/estatística & dados numéricos , Diabetes Mellitus Tipo 2/epidemiologia , Feminino , Nível de Saúde , Humanos , Vida Independente , Masculino , Pessoa de Meia-Idade , Boca Edêntula/epidemiologia , Prevalência , Saliva/metabolismo , Classe Social , Inquéritos e Questionários , Local de Trabalho , Xerostomia/epidemiologia
19.
Int Dent J ; 70(6): 427-434, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32830311

RESUMO

OBJECTIVE: Determine the accuracy of a questionnaire on xerostomia as a screening tool for hyposalivation. METHODS: A total of 402 adults awaiting dental care at a public healthcare service answered an eight-item questionnaire addressing xerostomia and were submitted to stimulated sialometry, with ≤ 0.7 mL/min considered indicative of hyposalivation. Reproducibility and internal consistency of the questionnaire were evaluated. The correlation between the score and salivary flow was investigated. The total score was also compared between groups with and without hyposalivation and diagnostic precision measures were calculated. RESULTS: Hyposalivation was identified in 162 participants (40.3%) and a total of 229 (57.0%) answered affirmatively to at least one question. The responses to each question revealed variable reproducibility (κ = 0.450-0.785) and satisfactory internal consistency (Cronbach's α = 0.70). Individuals with a larger number of positive answers had lower salivary flow (Spearman's ρ = -0.193; P < 0.001). The mean number of positive answers was greater in the group with a clinical diagnosis of hyposalivation compared to those without low salivary flow. The sensitivity of the screening tool was 64.8%, with an area under the ROC curve of 0.60 (95% confidence interval: 0.547-0.645; P < 0.001). CONCLUSION: The questionnaire proved to be useful for the epidemiological screening of individuals with possible hyposalivation.


Assuntos
Xerostomia , Adulto , Humanos , Programas de Rastreamento , Curva ROC , Reprodutibilidade dos Testes , Saliva , Inquéritos e Questionários , Xerostomia/diagnóstico
20.
J Voice ; 33(5): 806.e1-806.e7, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29678439

RESUMO

OBJECTIVES: This study aimed to estimate the prevalence and factors associated with voice disorders (VDs) in Brazilian community-dwelling older adults. STUDY DESIGN: This is a cross-sectional study. METHODS: The sample comprised 463 older adults (60 years or more) of both sexes living in a Brazilian northeastern city. Variables were related to socioeconomic and demographic profile, lifestyle, and general health conditions, in addition to the validated "Screening for Voice Disorders in Older Adults" (RAVI) questionnaire. A bivariate analysis was performed using the Pearson chi-square test or the Fisher exact test, and the magnitude of the association was the prevalence ratio (PR). Poisson regression model was performed, considering only the variables with a critical value of P < 0.20. The significance level was 5%. RESULTS: There was a prevalence of women (60.9%), and the average age of participants was 70 (±7.74) years. The prevalence of VDs was 51.4% (95% confidence interval [CI]: 46.8-55.9). The most common symptoms were throat sensation of phlegm (46.9%) and dry throat (46.7%), both related to physical sensations of laryngeal discomfort. Multivariate analysis indicated that the prevalence of VDs was independently associated with hyposalivation (PR = 2.28, 95% CI = 1.80-2.88), smoking (PR = 2.04, 95% CI = 1.65-2.52), self-reported hearing loss (PR = 1.51, 95% CI = 1.28-1.78), and not seeking a physician or other health professional care for VDs (PR = 0.73, 95% CI = 0.60-0.88). CONCLUSION: VDs are prevalent among Brazilian community-dwelling older adults and are associated with variables related to general health and lifestyle.


Assuntos
Distúrbios da Voz/epidemiologia , Idoso , Brasil/epidemiologia , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência
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