Detalhe da pesquisa
1.
Plasmin-cleaved von Willebrand factor as a biomarker for microvascular thrombosis.
Blood
; 143(20): 2089-2098, 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38271661
2.
VWF-targeted thrombolysis to overcome rh-tPA resistance in experimental murine ischemic stroke models.
Blood
; 140(26): 2844-2848, 2022 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35960811
3.
Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis.
Blood
; 139(4): 597-607, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34752601
4.
A reactive center loop-based prediction platform to enhance the design of therapeutic SERPINs.
Proc Natl Acad Sci U S A
; 118(45)2021 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34740972
5.
Restriction of C1-inhibitor activity in hereditary angioedema by dominant-negative effects of disease-associated SERPING1 gene variants.
J Allergy Clin Immunol
; 152(5): 1218-1236.e9, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37301409
6.
A mutation in the kringle domain of human factor XII that causes autoinflammation, disturbs zymogen quiescence, and accelerates activation.
J Biol Chem
; 295(2): 363-374, 2020 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31771982
7.
Design and characterization of α1-antitrypsin variants for treatment of contact system-driven thromboinflammation.
Blood
; 134(19): 1658-1669, 2019 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31366623
8.
Evidence for bradykinin release in chronic spontaneous urticaria.
Clin Exp Allergy
; 50(3): 343-351, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31899843
9.
Polyphosphate nanoparticles on the platelet surface trigger contact system activation.
Blood
; 129(12): 1707-1717, 2017 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28049643
10.
Antihistone Properties of C1 Esterase Inhibitor Protect against Lung Injury.
Am J Respir Crit Care Med
; 196(2): 186-199, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28005404
11.
Plasmin is a natural trigger for bradykinin production in patients with hereditary angioedema with factor XII mutations.
J Allergy Clin Immunol
; 138(5): 1414-1423.e9, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27130860
12.
Keeping von Willebrand Factor under Control: Alternatives for ADAMTS13.
Semin Thromb Hemost
; 42(1): 9-17, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26595154
13.
Detecting oral kallikrein-targeting therapy through triggered contact activation: A phase I study.
J Allergy Clin Immunol
; 146(6): 1446-1449.e5, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32360287
14.
Invasive surgery reduces infarct size and preserves cardiac function in a porcine model of myocardial infarction.
J Cell Mol Med
; 19(11): 2655-63, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26282710
15.
Plasmin cleavage of von Willebrand factor as an emergency bypass for ADAMTS13 deficiency in thrombotic microangiopathy.
Circulation
; 129(12): 1320-31, 2014 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24449821
16.
Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection.
Semin Thromb Hemost
; 46(7): 835-837, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32526773
17.
Contact system activation on endothelial cells.
Semin Thromb Hemost
; 40(8): 887-94, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25389102
18.
Cleaved kininogen as a biomarker for bradykinin release in hereditary angioedema.
J Allergy Clin Immunol
; 140(6): 1700-1703.e8, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28782632
19.
Factor XII Explored with AlphaFold - Opportunities for Selective Drug Development.
Thromb Haemost
; 123(2): 177-185, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36167333
20.
Insights in the Prothrombotic Changes After Implantation of a Left Ventricular Assist Device in Patients With End-Stage Heart Failure: A Longitudinal Observational Study.
ASAIO J
; 69(5): 438-444, 2023 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36730294