RESUMO
We described an 18 old homosexual man who after 5 days developed a neurologic picture associated with Human Immunodeficiency Viruses (HIV) seroconversion. The patient had developed a dissociative psychiatric disorder 6 months before, and after resolution of the acute neurologic disease a mild neuro-psychiatric disorder remained. After mononucleosis-like syndrome of three weeks, the patient developed a meningo-encephalitic process 48 h post admission. He evolved with tonic seizures and twilight state and was admitted into Intensive Care Unit because of epileptic status and deep coma. Evolution was favourable after 72 h of treatment with acyclovir and antiepileptic drugs. Laboratory data showed an inverted T4/T8 ratio and seroconversion to HIV-antibodies and p24-antigen both in serum and CSF. These observations confirm the existence of psychiatric as well neurological alterations in acute HIV infection, and also the significance of p24-antigen and Western-Blot in serum and CSF in showing the seroconversion profile.
Assuntos
Transtornos Dissociativos/complicações , Infecções por HIV/complicações , HIV-1/isolamento & purificação , Mononucleose Infecciosa/microbiologia , Meningoencefalite/microbiologia , Estado Epiléptico/etiologia , Doença Aguda , Adolescente , Anticorpos Antivirais/sangue , Western Blotting , Relação CD4-CD8 , Transtornos Dissociativos/diagnóstico , Anticorpos Anti-HIV/sangue , Proteína do Núcleo p24 do HIV/sangue , Proteína do Núcleo p24 do HIV/líquido cefalorraquidiano , Infecções por HIV/sangue , Infecções por HIV/líquido cefalorraquidiano , Infecções por HIV/imunologia , HIV-1/patogenicidade , Herpesviridae/imunologia , Humanos , Masculino , Meningoencefalite/líquido cefalorraquidiano , Meningoencefalite/complicaçõesRESUMO
The study of 156 cases HIV infected patients put forward the high incidence of ENT manifestations in these cases. Cervical lymph nodes are an habitual manifestation of the disease. They appear as a host reaction versus viral infection and often they are the expression of opportunistic infection, Kaposi Sarcoma or lymphoma. They also have prognostic significance. We think that the lowe incidence of Kaposi Sarcoma in our report (comparing with other authors rates) is due to the fact that there is a smaller population of homosexuals in our environment.