Detalhe da pesquisa
1.
Computational drug prediction in hepatoblastoma by integrating pan-cancer transcriptomics with pharmacological response.
Hepatology
; 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37729391
2.
A yeast synthetic network for in vivo assessment of reverse-engineering and modeling approaches.
Cell
; 137(1): 172-81, 2009 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19327819
3.
Definition of the transcriptional units of inherited retinal disease genes by meta-analysis of human retinal transcriptome data.
BMC Genomics
; 24(1): 206, 2023 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37072692
4.
Pharmacoproteomics pinpoints HSP70 interaction for correction of the most frequent Wilson disease-causing mutant of ATP7B.
Proc Natl Acad Sci U S A
; 117(51): 32453-32463, 2020 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33288711
5.
A Siamese neural network model for the prioritization of metabolic disorders by integrating real and simulated data.
Bioinformatics
; 36(Suppl_2): i787-i794, 2020 12 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33381827
6.
Drug Repurposing in Rare Diseases: An Integrative Study of Drug Screening and Transcriptomic Analysis in Nephropathic Cystinosis.
Int J Mol Sci
; 22(23)2021 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884638
7.
gep2pep: a Bioconductor package for the creation and analysis of pathway-based expression profiles.
Bioinformatics
; 2019 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31647521
8.
TRPV4 and purinergic receptor signalling pathways are separately linked in airway epithelia to CFTR and TMEM16A chloride channels.
J Physiol
; 597(24): 5859-5878, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31622498
9.
Comprehensive kinome NGS targeted expression profiling by KING-REX.
BMC Genomics
; 20(1): 307, 2019 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31014245
10.
gene2drug: a computational tool for pathway-based rational drug repositioning.
Bioinformatics
; 34(9): 1498-1505, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29236977
11.
High-resolution analysis of the human retina miRNome reveals isomiR variations and novel microRNAs.
Nucleic Acids Res
; 44(4): 1525-40, 2016 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26819412
12.
An atlas of gene expression and gene co-regulation in the human retina.
Nucleic Acids Res
; 44(12): 5773-84, 2016 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27235414
13.
Drug-set enrichment analysis: a novel tool to investigate drug mode of action.
Bioinformatics
; 32(2): 235-41, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26415724
14.
Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress.
Carcinogenesis
; 37(1): 39-48, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26542370
15.
A reverse-engineering approach to dissect post-translational modulators of transcription factor's activity from transcriptional data.
BMC Bioinformatics
; 16: 279, 2015 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26334955
16.
The phytoestrogen genistein modulates lysosomal metabolism and transcription factor EB (TFEB) activation.
J Biol Chem
; 289(24): 17054-69, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24770416
17.
Blood transcriptomics of drug-naïve sporadic Parkinson's disease patients.
BMC Genomics
; 16: 876, 2015 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26510930
18.
Mantra 2.0: an online collaborative resource for drug mode of action and repurposing by network analysis.
Bioinformatics
; 30(12): 1787-8, 2014 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24558125
19.
In-vivo real-time control of protein expression from endogenous and synthetic gene networks.
PLoS Comput Biol
; 10(5): e1003625, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24831205
20.
Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation.
Nucleic Acids Res
; 41(2): 711-26, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23180766