RESUMO
BACKGROUND: Therapy with elastic compression stockings has been the cornerstone for prevention of post-thrombotic syndrome for decades in patients after acute deep venous thrombosis. It is uncertain who benefits most from therapy, and what the optimum duration of therapy should be. We therefore aimed to assess the safety and efficacy of individualised duration of compression therapy versus the standard duration of 24 months following an initial treatment period of 6 months. METHODS: We did a multicentre, randomised, single-blind, allocation-concealed, non-inferiority trial at 12 hospitals in the Netherlands and two in Italy. We randomly assigned patients (1:1) with acute proximal deep vein thrombosis of the leg and without pre-existent venous insufficiency (Clinical Etiological Anatomical and Pathophysiological score Assuntos
Síndrome Pós-Trombótica/prevenção & controle
, Meias de Compressão
, Adulto
, Idoso
, Feminino
, Humanos
, Masculino
, Pessoa de Meia-Idade
, Padrões de Referência
, Segurança
, Método Simples-Cego
, Meias de Compressão/efeitos adversos
, Fatores de Tempo
, Resultado do Tratamento